Search Results - "Swenson, Christina D."

Abstract 512: Tetramer and pentamer assays for antigen-specific lymphocytes: Implementation in clinical trials by Xue, Chengsen, Zhong, Weiguo, Cho, Yeji, Cuomo, Joanne, Swenson, Christina D., Closkey, Thomas W. Mc

“…Abstract The success of inhibiting PD1 on T cells for cancer immunotherapy initiated strong interest in studying therapeutic antibodies to alter the adaptive…”
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Abstract 5588: Uneven distribution of CTCs in magnetic fields following binding with iron nanoparticles by Xue, Chengsen, Swenson, Christina D., Closkey, Thomas W. Mc

“…Abstract Circulating tumor cell (CTC) detection and characterization have recently become an integral part of precision medicine. Several large, multicenter…”
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Abstract 1171: Estimating sensitivity of exploratory cellular biomarkers in oncology clinical trials by Xue, Chengsen, Swenson, Christina D., Mc Closkey, Thomas W.

“…Abstract Background: In the prolonged and complex process of assessing immunotherapeutic oncology drug candidates, flow cytometry plays an essential role. In…”
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The effect of aging on the immune response: influence of phosphatidylcholine-containing lipid on IgD-receptor expression and antibody formation by Swenson, Christina D, Gottesman, Susan R.S, Xue, Bin, Edington, Joanne, Thorbecke, G.Jeanette

“…It was reported previously that IgD-receptors (IgD-R) are expressed on both CD4 + and CD8 + human T cells and CD4 + murine T cells after exposure to oligomeric…”
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Human T cell IgD receptors react with O‐glycans on both human IgD and IgA1 by Swenson, Christina D., Patel, Thakor, Parekh, Raj B., Tamma, S. M. Lakshmi, Coico, Richard F., Thorbecke, G. Jeanette, Amin, Ashok R.

“…Previous studies on murine T cell IgD‐R have shown that these receptors recognize N‐glycans of murine IgD, and not of other Ig isotypes. We have now studied…”
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The effect of aging on IgD receptor expression by T cells and its functional implications by Swenson, Christina D., Thorbecke, G. Jeanette

“…Exposure to oligomeric or aggregated (a), but not to mono‐merle (m), IgD causes a rapid (within 1 h) upregulation of IgD‐R expression on CD4+ T cells from…”
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Oligomeric IgD augments and monomeric IgD inhibits the generation of IgG memory antibody responses in normal, but not in IgD-deficient, mice by Swenson, CD, Rizinashvili, E, Amin, AR, Thorbecke, GJ

“…Dimeric or aggregated IgD causes augmentation of primary and secondary Ab responses in mice when injected a few days before or together with the primary dose…”
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IgD-receptor up-regulation on human peripheral blood T cells in response to IgD in vitro or antigen in vivo correlates with the antibody response to influenza vaccination by Swenson, C D, Cherniack, E P, Russo, C, Thorbecke, G J

“…Aged individuals (more than 65 years) were classified as antibody (Ab) responders on the basis that they showed increases to more than or = 1:40 in serum Ab…”
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Relationship between humoral immunoaugmenting properties of DHEAS and IgD-receptor expression in young and aged mice by Swenson, C D, Gottesman, S R, Belsito, D V, Samanich, K M, Edington, J, Thorbecke, G J

“…IgD-receptors are associated with augmented antibody production in vivo and are induced on CD4+ T cells by aggregated IgD in young but not in aged mice. In the…”
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Regulation of IgD-receptor expression on murine T cells. I. Characterization and metabolic requirements of the process leading to their expression by Swenson, C D, Amin, A R, Xue, B, Thorbecke, G J

“…Receptors for IgD (IgD-R) are found on murine CD4+ T cells and T cell clones. Previous work has shown that incubation with aggregated (but not monomeric) IgD…”
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Regulation of IgD-receptor expression on murine T cells. II. Upregulation of IgD receptors is obtained after activation of various intracellular second-messenger systems; tyrosine kinase activity is required for the effect of IgD by Amin, A R, Swenson, C D, Xue, B, Ishida, Y, Nair, B G, Patel, T B, Chused, T M, Thorbecke, G J

“…The presence of IgD receptors (IgD-R) on T cells during a primary response to antigen causes augmented antibody production and facilitates priming for a…”
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Exposure to Crosslinked IgD Induces Receptors for IgD on T Cells in vivo and in vitro by Coico, Richard F., Finkelman, Fred, Swenson, Christina D., Siskind, Gregory W., Thorbecke, G. Jeanette

“…IgD is a surface immunoglobulin, which is coexpressed with IgM on >90% of mature B cells, but its levels in serum are extremely low compared to those of IgM…”
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Physiology of IgD. IX. Effect of IgD on immunoglobulin production in young and old mice by Swenson, C D, Van Vollenhoven, R F, Xue, B, Siskind, G W, Thorbecke, G J, Coico, R F

“…Weekly i.p. injections of IgD from birth in (SJL X BALB/c)F1 mice were found to accelerate the development of IgG- and IgA-secreting cells and to increase the…”
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Serum IgD levels in mice: effect of strain, age and autoimmune disease by van Vollenhoven, R F, Swenson, C D, Soriano, A, Goidl, E A, Coico, R F, Thorbecke, G J, Siskind, G W

“…Serum IgD levels were studied in mice. Strain-related variability of serum IgD levels was noted, and advanced age was associated with markedly increased IgD…”
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