Search Results - "Swenn, Kristin"

Mechanism of inactivation of human O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine by Pegg, Anthony E, Boosalis, Michael, Samson, Leona, Moschel, Robert C, Byers, Timothy L, Swenn, Kristin, Dolan, M. Eileen

“…Human O6-alkylguanine-DNA alkyltransferase was rapidly inactivated by low concentrations of O6-benzylguanine, but the alkyltransferase from the Escherichia…”
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Increased killing of prostate, breast, colon, and lung tumor cells by the combination of inactivators of O6-alkylguanine-DNA alkyltransferase and N, N′- bis(2-chloroethyl)- N-nitrosourea by Pegg, Anthony E., Swenn, Kristin, Mi-Young, Chae, Dolan, M.Eileen, Moschel, Robert C.

“…The ability of a number of compounds that act as inactivators of O 6-alkylguanine-DNA alkyltransferase (AGT) to sensitize human tumor cell lines to the effects…”
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8-Substituted O6-Benzylguanine, Substituted 6(4)-(Benzyloxy)pyrimidine, and Related Derivatives as Inactivators of Human O6-Alkylguanine-DNA Alkyltransferase by Chae, Mi-Young, Swenn, Kristin, Kanugula, Sreenivas, Dolan, M. Eileen, Pegg, Anthony E, Moschel, Robert C

“…Several 8-substituted O6-benzylguanines, 2- and/or 8-substituted 6-(benzyloxy)purines, substituted 6(4)-(benzyloxy)pyrimidines, and a 6-(benzyloxy)-s-triazine…”
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Substituted O6-Benzylguanine Derivatives and Their Inactivation of Human O6-Alkylguanine-DNA Alkyltransferase by Chae, Mi Young, McDougall, Mark G, Dolan, M. Eileen, Swenn, Kristin, Pegg, Anthony E, Moschel, Robert C

“…Several new O6-benzylguanine analogs bearing increasingly bulky substituent groups on the benzene ring or at position 9 were tested for their ability to…”
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