Search Results - "Swellmeen, Lubna"

Preparation and Characterization of Patch Loaded with Clarithromycin Nanovesicles for Transdermal Drug Delivery by Zaid Alkilani, Ahlam, Musleh, Batool, Hamed, Rania, Swellmeen, Lubna, Basheer, Haneen A

“…Clarithromycin (CLR), categorized as a Biopharmaceutical Classification System class II drug, has several gastrointestinal tract side effects and an extremely…”
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Identification of novel inhibitors for Pim-1 kinase using pharmacophore modeling based on a novel method for selecting pharmacophore generation subsets by Shahin, Rand, Swellmeen, Lubna, Shaheen, Omar, Aboalhaija, Nour, Habash, Maha

“…Targeting Proviral integration-site of murine Moloney leukemia virus 1 kinase, hereafter called Pim-1 kinase, is a promising strategy for treating different…”
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Structure based drug design of Pim-1 kinase followed by pharmacophore guided synthesis of quinolone-based inhibitors by Swellmeen, Lubna, Shahin, Rand, Al-Hiari, Yusuf, Alamiri, Amani, Hasan, Alaa, Shaheen, Omar

“…[Display omitted] •104 crystal structure of Pim-1 kinase were collected from the Protein Data Bank.•The co-crystallized ligand-Pim 1 kinase receptor…”
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Leptin and systemic lupus erythematosus: A comprehensive review by Uzrail, Amal H, Swellmeen, Lubna

“…Leptin, a cytokine-like hormone produced by adipocytes, modulates innate and adaptive responses of the immune system. Several reports have indicated that…”
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Formulation and Evaluation of Azithromycin-Loaded Niosomal Gel: Optimization, In Vitro Studies, Rheological Characterization, and Cytotoxicity Study by Zaid Alkilani, Ahlam, Hamed, Rania, Abdo, Hajer, Swellmeen, Lubna, Basheer, Haneen A., Wahdan, Walaa, Abu Kwiak, Amani D.

“…Several novel, innovative approaches for improving transdermal delivery of BCS class III drugs have been proposed. Despite their great aqueous solubility, BCS…”
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Targeting GSK-3β enzyme by diazepino-quinolone derivatives by Swellmeen, Lubna, Basheer, Haneen A, Uzrail, Amal, Sallam, Haneen, Al-Hiari, Yusuf, Alkilani, Ahlam

“…Purpose: To synthesize a heterocyclic system containing quinolone and diazepine scaffolds as GSK-3β inhibitor. Methods: The diazepino-quinoline derivatives…”
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Molecular modelling studies and synthesis of novel quinoxaline derivatives with potential inhibitory effect on GSK-3β by Swellmeen, Lubna, Uzrail, Amal, Shaheen, Rand, Al-Hiari, Yusuf

“…Purpose: To synthesize quinoxaline derivatives and investigate their inhibitory effects on glycogen synthase kinase (GSK)-3β in vitro. Methods: Quinoxaline…”
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Ligand-based computer aided drug design reveals new tropomycin receptor kinase a (TrkA) inhibitors by Shahin, Rand, Mansi, Iman, Swellmeen, Lubna, Alwidyan, Tahani, Al-Hashimi, Nabil, Al-Qarar’h, Yaser, Shaheen, Omar

“…[Display omitted] •161 TrkA inhibitors were modeled by a combination pharmacophore and Genetic algorithm regression QSAR workflow.•The pharmacophore generation…”
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