Search Results - "Sweet, Robert M"

Hepatitis C virus NS3/4A inhibitors and other drug-like compounds as covalent binders of SARS-CoV-2 main protease by Andi, Babak, Kumaran, Desigan, Kreitler, Dale F., Soares, Alexei S., Keereetaweep, Jantana, Jakoncic, Jean, Lazo, Edwin O., Shi, Wuxian, Fuchs, Martin R., Sweet, Robert M., Shanklin, John, Adams, Paul D., Schmidt, Jurgen G., Head, Martha S., McSweeney, Sean

“…Severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2), which causes coronavirus disease 2019 (COVID-19), threatens global public health. The world needs…”
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Variability of tissue mechanical response in Sus Domesticus porcine models from in vivo to ex vivo conditions by Malik, Faizan A, Drahos, Bradley A, Safdari, Amer M, Mazzeo, Mark V, Norfleet, Jack E, Sweet, Robert M, Kowalewski, Timothy M

“…Healthcare simulators have been demonstrated to be a valuable resource for training several technical and nontechnical skills. A gap in the fidelity of tissues…”
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A simple technique to classify diffraction data from dynamic proteins according to individual polymorphs by Nguyen, Thu, Phan, Kim L., Kozakov, Dima, Gabelli, Sandra B., Kreitler, Dale F., Andrews, Lawrence C., Jakoncic, Jean, Sweet, Robert M., Soares, Alexei S., Bernstein, Herbert J.

“…One often observes small but measurable differences in the diffraction data measured from different crystals of a single protein. These differences might…”
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Development and Validation of a Basic Arthroscopy Skills Simulator by Braman, Jonathan P., M.D, Sweet, Robert M., M.D, Hananel, David M., B.A., B.S, Ludewig, Paula M., Ph.D, Van Heest, Ann E., M.D

“…Purpose The purpose of our study was to develop a low-fidelity surgical simulator for basic arthroscopic skills training, with the goal of creating a…”
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The Advanced Modular Manikin Open Source Platform for Healthcare Simulation by Hananel, David, Silverglate, Dan, Burke, Dan, Riggs, Benjamin, Norfleet, Jack, Sweet, Robert M

“…ABSTRACT Introduction Current thinking in healthcare education stipulates a holistic approach with a focus on patient management, bringing together technical…”
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Best practices across surgical specialties relating to simulation-based training by Gardner, Aimee K., PhD, Scott, Daniel J., MD, Pedowitz, Robert A., MD, PhD, Sweet, Robert M., MD, Feins, Richard H., MD, Deutsch, Ellen S., MD, Sachdeva, Ajit K., MD

“…Introduction Simulation-based training is playing an increasingly important role in surgery. However, there is insufficient discussion among the surgical…”
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AMX – the highly automated macromolecular crystallography (17‐ID‐1) beamline at the NSLS‐II by Schneider, Dieter K., Soares, Alexei S., Lazo, Edwin O., Kreitler, Dale F., Qian, Kun, Fuchs, Martin R., Bhogadi, Dileep K., Antonelli, Steve, Myers, Stuart S., Martins, Bruno S., Skinner, John M., Aishima, Jun, Bernstein, Herbert J., Langdon, Thomas, Lara, John, Petkus, Robert, Cowan, Matt, Flaks, Leonid, Smith, Thomas, Shea-McCarthy, Grace, Idir, Mourad, Huang, Lei, Chubar, Oleg, Sweet, Robert M., Berman, Lonny E., McSweeney, Sean, Jakoncic, Jean

“…The highly automated macromolecular crystallography beamline AMX/17‐ID‐1 is an undulator‐based high‐intensity (>5 × 1012 photons s−1), micro‐focus (7 µm × 5…”
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Surgical simulation: a urological perspective by Wignall, Geoffrey R, Denstedt, John D, Preminger, Glenn M, Cadeddu, Jeffrey A, Pearle, Margaret S, Sweet, Robert M, McDougall, Elspeth M

“…Surgical education is changing rapidly as several factors including budget constraints and medicolegal concerns limit opportunities for urological trainees…”
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Sensorized tissue analogues enabled by a 3D-printed conductive organogel by Crump, Michael R., Bidinger, Sophia L., Pavinatto, Felippe J., Gong, Alex T., Sweet, Robert M., MacKenzie, J. Devin

“…State-of-the-art tissue analogues used in high-fidelity, hands-on medical simulation modules can deliver lifelike appearance and feel but lack the capability…”
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The Catalytic Pathway of Cytochrome P450cam at Atomic Resolution by Schlichting, Ilme, Berendzen, Joel, Chu, Kelvin, Stock, Ann M., Maves, Shelley A., Benson, David E., Sweet, Robert M., Ringe, Dagmar, Petsko, Gregory A., Sligar, Stephen G.

“…Members of the cytochrome P450 superfamily catalyze the addition of molecular oxygen to nonactivated hydrocarbons at physiological temperature-a reaction that…”
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Crystal Structures of Myoglobin-Ligand Complexes at Near-Atomic Resolution by Vojtěchovský, Jaroslav, Chu, Kelvin, Berendzen, Joel, Sweet, Robert M., Schlichting, Ilme

“…We have used x-ray crystallography to determine the structures of sperm whale myoglobin (Mb) in four different ligation states (unligated, ferric aquomet,…”
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Simulation-based summative assessments in surgery by Szasz, Peter, MD, Grantcharov, Teodor P., MD, PhD, FACS, Sweet, Robert M., MD, FACS, Korndorffer, James R., MD, MPHE, FACS, Pedowitz, Robert A., MD, PhD, FACS, Roberts, Patricia L., MD, FASCRS, FACS, Sachdeva, Ajit K., MD, FRCSC, FACS

“…Background The American College of Surgeons-Accredited Education Institutes (ACS-AEI) Consortium aims to enhance patient safety and advance surgical education…”
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The CREST Simulation Development Process: Training the Next Generation by Sweet, Robert M

“…The challenges of training and assessing endourologic skill have driven the development of new training systems. The Center for Research in Education and…”
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Structure of a ligand-binding intermediate in wild-type carbonmonoxy myoglobin by Schlichting, Ilme, Chu, Kelvin, Vojtchovský, Jaroslav, McMahon, Benjamin H, Sweet, Robert M, Berendzen, Joel

“…Small molecules such as NO, O2, CO or H2 are important biological ligands that bind to metalloproteins to function crucially in processes such as signal…”
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A linear relationship between crystal size and fragment binding time observed crystallographically: implications for fragment library screening using acoustic droplet ejection by Cole, Krystal, Roessler, Christian G, Mulé, Elizabeth A, Benson-Xu, Emma J, Mullen, Jeffrey D, Le, Benjamin A, Tieman, Alanna M, Birone, Claire, Brown, Maria, Hernandez, Jesus, Neff, Sherry, Williams, Daniel, Allaire, Marc, Orville, Allen M, Sweet, Robert M, Soares, Alexei S

“…High throughput screening technologies such as acoustic droplet ejection (ADE) greatly increase the rate at which X-ray diffraction data can be acquired from…”
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Ureteral Strictures Following Ureteroscopy for Kidney Stone Disease: A Population-based Assessment by Sunaryo, Peter L, May, Philip C, Holt, Sarah K, Sorensen, Matthew D, Sweet, Robert M, Harper, Jonathan D

“…As the prevalence of urolithiasis increases and ureteroscopy is used more frequently, the risks of uncommon complications such as ureteral stricture may become…”
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Single-crystal Raman spectroscopy and X-ray crystallography at beamline X26-C of the NSLS by Stoner-Ma, Deborah, Skinner, John M., Schneider, Dieter K., Cowan, Matt, Sweet, Robert M., Orville, Allen M.

“…Three‐dimensional structures derived from X‐ray diffraction of protein crystals provide a wealth of information. Features and interactions important for the…”
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Correlated single-crystal electronic absorption spectroscopy and X-ray crystallography at NSLS beamline X26-C by Orville, Allen M., Buono, Richard, Cowan, Matt, Héroux, Annie, Shea-McCarthy, Grace, Schneider, Dieter K., Skinner, John M., Skinner, Michael J., Stoner-Ma, Deborah, Sweet, Robert M.

“…The research philosophy and new capabilities installed at NSLS beamline X26‐C to support electronic absorption and Raman spectroscopies coupled with X‐ray…”
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A Call for a Shift in Theory and Terminology for Validation Studies in Urological Education by Noureldin, Yasser A., Sweet, Robert M.

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Simulation and Computer-Animated Devices: The New Minimally Invasive Skills Training Paradigm by Sweet, Robert M., MD, McDougall, Elspeth M., MD, FRCSC

“…Complex surgical technologies, restricted resident work hours, and limited case volumes in surgical practice have created new challenges to surgical education…”
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