Search Results - "Sweet, Charles"

A Multimodal System for Lipid A Structural Analysis from a Single Colony by Yang, Hyojik, O'Keefe, Ian, Smith, Richard D, Sumner, Kylie P, Sherman, Matthew E, Goodlett, David R, Sweet, Charles R, Ernst, Robert K

“…Structural elucidation of Gram-negative bacterial lipid A traditionally requires chemical extraction followed by tandem MS data in the negative ion mode…”
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Structure Determination of Lipid A with Multiple Glycosylation Sites by Tandem MS of Lithium-Adducted Negative Ions by Yang, Hyojik, Sherman, Matthew E., Koo, Caitlyn J., Treaster, Logan M., Smith, Joseph P., Gallaher, Shawn G., Goodlett, David R., Sweet, Charles R., Ernst, Robert K.

“…FLATn is a tandem mass spectrometric technique that can be used to rapidly generate spectral information applicable for structural elucidation of lipids like…”
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Serine/threonine acetylation of TGFβ-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling by Paquette, Nicholas, Conlon, Joseph, Sweet, Charles, Rus, Florentina, Wilson, Lindsay, Pereira, Andrea, Rosadini, Charles V, Goutagny, Nadege, Weber, Alexander N. R, Lane, William S, Shaffer, Scott A, Maniatis, Stephanie, Fitzgerald, Katherine A, Stuart, Lynda, Silverman, Neal

“…The Gram-negative bacteria Yersinia pestis , causative agent of plague, is extremely virulent. One mechanism contributing to Y. pestis virulence is the…”
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Virulence factors of Yersinia pestis are overcome by a strong lipopolysaccharide response by Lien, Egil, Montminy, Sara W, Khan, Naseema, McGrath, Sara, Walkowicz, Mitchell J, Sharp, Fiona, Conlon, Joseph E, Fukase, Koichi, Kusumoto, Shoichi, Sweet, Charles, Miyake, Kensuke, Akira, Shizuo, Cotter, Robert J, Goguen, Jon D

“…At mammalian body temperature, the plague bacillus Yersinia pestis synthesizes lipopolysaccharide (LPS)-lipid A with poor Toll-like receptor 4…”
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YopJ targets TRAF proteins to inhibit TLR-mediated NF-κB, MAPK and IRF3 signal transduction by Sweet, Charles R, Conlon, Joseph, Golenbock, Douglas T, Goguen, Jon, Silverman, Neal

“…The Yersinia pestis virulence factor YopJ is a potent inhibitor of the NF-κB and MAPK signalling pathways, however, its molecular mechanism and relevance to…”
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Temperature-Dependence of Lipid A Acyl Structure in Psychrobacter cryohalolentis and Arctic Isolates of Colwellia hornerae and Colwellia piezophila by Sweet, Charles R, Watson, Rebecca E, Landis, Corinne A, Smith, Joseph P

“…Lipid A is a fundamental Gram-negative outer membrane component and the essential element of lipopolysaccharide (endotoxin), a potent immunostimulatory…”
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Characterization of Pseudomonas aeruginosa from subjects with diffuse panbronchiolitis by Met, Charles M, Hofstaedter, Casey E, O'Keefe, Ian P, Yang, Hyojik, Moustafa, Dina A, Sherman, Matthew E, Doi, Yohei, Rasko, David A, Sweet, Charles R, Goldberg, Joanna B, Ernst, Robert K

“…Diffuse panbronchiolitis (DPB) is a rare, idiopathic inflammatory disease primarily diagnosed in East Asian populations. DPB is characterized by diffuse…”
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Meeting report of the seventh annual Tri-Service Microbiome Consortium Symposium by Liechty, Zachary S., Agans, Richard T., Barbato, Robyn A., Colston, Sophie M., Christian, Monica R., Hammamieh, Rasha, Kardish, Melissa R., Karl, J. Philip, Leary, Dagmar H., Mauzy, Camilla A., de Goodfellow, Ida Pantoja-Feliciano, Racicot, Kenneth, Soares, Jason W., Stamps, Blake W., Sweet, Charles R., Tuck, Sara M., Whitman, Jordan A., Goodson, Michael S.

“…Abstract The Tri-Service Microbiome Consortium (TSMC) was founded to enhance collaboration, coordination, and communication of microbiome research among DoD…”
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Endotoxin structures in the psychrophiles Psychromonas marina and Psychrobacter cryohalolentis contain distinctive acyl features by Sweet, Charles R, Alpuche, Giancarlo M, Landis, Corinne A, Sandman, Benjamin C

“…Lipid A is the essential component of endotoxin (Gram-negative lipopolysaccharide), a potent immunostimulatory compound. As the outer surface of the outer…”
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Oxidation and transamination of the 3"-position of UDP-N-acetylglucosamine by enzymes from Acidithiobacillus ferrooxidans. Role in the formation of lipid a molecules with four amide-linked acyl chains by Sweet, Charles R, Ribeiro, Anthony A, Raetz, Christian R H

“…Lipid A, a major component of the outer membranes of Escherichia coli and other Gram-negative bacteria, is usually constructed around a beta-1',6-linked…”
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Activation of the plant mitochondrial alternative oxidase: insights from site-directed mutagenesis by Umbach, Ann L., Gonzàlez-Meler, Miquel A., Sweet, Charles R., Siedow, James N.

“…The homodimeric cyanide-resistant alternative oxidase of plant mitochondria reduces oxygen to water without forming ATP. Arabidopsis thaliana alternative…”
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Expression of recombinant proteins from lac promoters by Sweet, Charles R

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Enzymatic synthesis of lipid A molecules with four amide-linked acyl chains. LpxA acyltransferases selective for an analog of UDP-N-acetylglucosamine in which an amine replaces the 3"-hydroxyl group by Sweet, Charles R, Williams, Allison H, Karbarz, Mark J, Werts, Catherine, Kalb, Suzanne R, Cotter, Robert J, Raetz, Christian R H

“…LpxA of Escherichia coli catalyzes the acylation of the glucosamine 3-OH group of UDP-GlcNAc, using R-3-hydroxymyristoyl-acyl carrier protein (ACP) as the…”
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A Randomized, Placebo-Controlled, Double-Blind, Parallel Study of Various Doses of Losartan Potassium Compared With Enalapril Maleate in Patients With Essential Hypertension by Gradman, Alan H, Arcuri, Karen E, Goldberg, Allan I, Ikeda, Leila S, Nelson, Edward B, Snavely, Duane B, Sweet, Charles S

“…The efficacy and safety of various doses of losartan potassium, a specific and selective angiotensin II receptor antagonist, were compared with those of…”
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Relaxed Acyl Chain Specificity of Bordetella UDP-N-acetylglucosamine Acyltransferases by Sweet, Charles R., Preston, Andrew, Toland, Elinor, Ramirez, Suzanne M., Cotter, Robert J., Maskell, Duncan J., Raetz, Christian R.H.

“…Lipid A (endotoxin) is a major structural component of Gram-negative outer membranes. It also serves as the hydrophobic anchor of lipopolysaccharide and is a…”
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Effects of Losartan on a Background of Hydrochlorothiazide in Patients With Hypertension by Soffer, Beth A, Wright, Jr, Pratt, J. Howard, Wiens, Brian, Goldberg, Allan I, Sweet, Charles S

“…The purpose of this multicenter trial was to compare the antihypertensive efficacy and safety of losartan potassium (losartan), a selective angiotensin II…”
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The SEC Finally Adopts Regulation AB II by Sweet, Charles A.

“…Regulation AB II represents the response of the U.S. SEC to a public perception that inadequate regulation of offerings of asset-backed securities (ABS) was a…”
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Aerobiotics: Toward the Discovery of New Antibiotics From Airborne Actinomycetes by Hudgens, Zachary, Wickard, Aaron, Nealon, Christopher, Sweet, Charles

“…In the last decade the rising prevalence of multi‐drug resistant (MDR) infections such as Staphylococcus, Acinetobacter, Klebsiella, Mycobacterium, and others…”
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Genomic signatures of cold adaptation in the family Colwelliaceae by Gentilhomme, Anais, Sweet, Charles, Hennon, Gwenn M. M., Collins, R. Eric

“…Psychrophily is a phenotype describing microbial growth at low temperatures; elucidating the biomolecular and genomic adaptations necessary for survival in the…”
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Investigating the structure of cold microbiomes: The Chesapeake Bay in winter and arctic North Slope in summer by Sweet, Charles, Koo, Caitlyn, Treaster, Logan, Cofer, Haven, Long, Katherine, Barker, Amanda, Douglas, Thomas, Gallaher, Shawn, Colston, Sophie, Smith, Joseph

“…The bacterial community (microbiome) of Arctic rivers, and of temperate rivers during winter, is of interest to ecologists and microbiologists as a unique…”
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