Search Results - "Sweep, C G"

Production of 11-Oxygenated Androgens by Testicular Adrenal Rest Tumors by Schröder, Mariska A M, Turcu, Adina F, O'Day, Patrick, van Herwaarden, Antonius E, Span, Paul N, Auchus, Richard J, Sweep, Fred C G J, Claahsen-van der Grinten, Hedi L

“…Testicular adrenal rest tumors (TART) are a common complication in males with classic 21-hydroxylase deficiency (21OHD). TART are likely to contribute to the…”
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Ten-year analysis of the prospective multicentre Chemo-N0 trial validates American Society of Clinical Oncology (ASCO)-recommended biomarkers uPA and PAI-1 for therapy decision making in node-negative breast cancer patients by Harbeck, N, Schmitt, M, Meisner, C, Friedel, C, Untch, M, Schmidt, M, Sweep, C.G.J, Lisboa, B.W, Lux, M.P, Beck, T, Hasmüller, S, Kiechle, M, Jänicke, F, Thomssen, C

“…Abstract Aim Final 10-year analysis of the prospective randomised Chemo-N0 trial is presented. Based on the Chemo-N0 interim results and an European…”
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Regulation of cytokine responses by seasonality of vitamin D status in healthy individuals by Khoo, A.-L, Chai, L.Y.A, Koenen, H.J.P.M, Sweep, F.C.G.J, Joosten, I, Netea, M.G, van der Ven, A.J.A.M

“…The immune modulating capacity of vitamin D₃ is well-recognized. Ultra-violet (UV) exposure determines production of vitamin D₃in vivo and varies through the…”
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Molecular Characterization of Testicular Adrenal Rest Tumors in Congenital Adrenal Hyperplasia: Lesions With Both Adrenocortical and Leydig Cell Features by Smeets, Evelien E. J. W, Span, Paul N, van Herwaarden, Antonius E, Wevers, Ron A, Hermus, Ad R. M. M, Sweep, Fred C. G. J, Claahsen-van der Grinten, Hedi L

“…Context: Testicular adrenal rest tumors (TART) are one of the major long term complications in patients with congenital adrenal hyperplasia. Although several…”
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Phosphoserine aminotransferase 1 is associated to poor outcome on tamoxifen therapy in recurrent breast cancer by De Marchi, Tommaso, Timmermans, Mieke A., Sieuwerts, Anieta M., Smid, Marcel, Look, Maxime P., Grebenchtchikov, Nicolai, Sweep, Fred C. G. J., Smits, Jan G., Magdolen, Viktor, van Deurzen, Carolien H. M., Foekens, John A., Umar, Arzu, Martens, John W.

“…In a previous study, we detected a significant association between phosphoserine aminotransferase 1 (PSAT1) hyper-methylation and mRNA levels to outcome to…”
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76-gene signature defines high-risk patients that benefit from adjuvant tamoxifen therapy by Zhang, Yi, Sieuwerts, Anieta M, McGreevy, Michelle, Casey, Graham, Cufer, Tanja, Paradiso, Angelo, Harbeck, Nadia, Span, Paul N, Hicks, David G, Crowe, Joseph, Tubbs, Raymond R, Budd, G. Thomas, Lyons, Joanne, Sweep, Fred C. G. J, Schmitt, Manfred, Schittulli, Francesco, Golouh, Rastko, Talantov, Dmitri, Wang, Yixin, Foekens, John A

“…Purpose To assess the benefit from adjuvant systemic tamoxifen therapy in breast cancer risk groups identified by the previously established prognostic 76-gene…”
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Bilateral Testicular Tumors Resulting in Recurrent Cushing Disease After Bilateral Adrenalectomy by Puar, Troy, Engels, Manon, van Herwaarden, Antonius E, Sweep, Fred C. G J, Hulsbergen-van de Kaa, Christina, Kamphuis-van Ulzen, Karin, Chortis, Vasileios, Arlt, Wiebke, Stikkelbroeck, Nike, Claahsen-van der Grinten, Hedi L, Hermus, Ad R. M M

“…CONTEXT:Recurrence of hypercortisolism in patients after bilateral adrenalectomy for Cushing disease is extremely rare. PATIENT:We present a 27-year-old man…”
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Regulation of TRIB3 mRNA and protein in breast cancer by Wennemers, Marloes, Bussink, Johan, van den Beucken, Twan, Sweep, Fred C G J, Span, Paul N

“…Tribbles homolog 3 (TRIB3) is a scaffold protein activated under hypoxic conditions and involved in several cell survival and proliferation pathways. Recently,…”
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Hypoxic regulation and prognostic value of LAMP3 expression in breast cancer by Nagelkerke, Anika, Mujcic, Hilda, Bussink, Johan, Wouters, Bradly G., van Laarhoven, Hanneke W. M., Sweep, Fred C. G. J., Span, Paul N.

“…BACKGROUND: LAMP3 is a newly described hypoxia regulated gene of potential interest in hypoxia‐induced therapy resistance and metastasis. The prognostic value…”
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Dipeptidyl-Peptidase-IV Inhibition Augments Postprandial Lipid Mobilization and Oxidation in Type 2 Diabetic Patients by Boschmann, Michael, Engeli, Stefan, Dobberstein, Kerstin, Budziarek, Petra, Strauss, Anke, Boehnke, Jana, Sweep, Fred C. G. J., Luft, Friedrich C., He, YanLing, Foley, James E., Jordan, Jens

“…Context: Dipeptidyl-peptidase-IV (DPP-4) inhibition increases endogenous GLP-1 activity, resulting in improved glycemic control in patients with type 2…”
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Randomized Adjuvant Chemotherapy Trial in High-Risk, Lymph Node-Negative Breast Cancer Patients Identified by Urokinase-Type Plasminogen Activator and Plasminogen Activator Inhibitor Type 1 by Jänicke, Fritz, Prechtl, Anita, Thomssen, Christoph, Harbeck, Nadia, Meisner, Christoph, Untch, Michael, Sweep, C. G. J. Fred, Selbmann, Hans-Konrad, Graeff, Henner, Schmitt, Manfred

“…Background: Most patients with lymph node-negative breast cancer are cured by locoregional treatment; however, about 30% relapse. Because traditional…”
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Downregulation of serine protease HTRA1 is associated with poor survival in breast cancer by Lehner, Anna, Magdolen, Viktor, Schuster, Tibor, Kotzsch, Matthias, Kiechle, Marion, Meindl, Alfons, Sweep, Fred C G J, Span, Paul N, Gross, Eva

“…HTRA1 is a highly conserved serine protease which has been implicated in suppression of epithelial-to-mesenchymal-transition (EMT) and cell motility in breast…”
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Genotype-Specific Differences in the Tumor Metabolite Profile of Pheochromocytoma and Paraganglioma Using Untargeted and Targeted Metabolomics by Rao, J. U, Engelke, U. F. H, Sweep, F. C. G. J, Pacak, K, Kusters, B, Goudswaard, A. G, Hermus, A. R. M. M, Mensenkamp, A. R, Eisenhofer, G, Qin, N, Richter, S, Kunst, H. P. M, Timmers, H. J. L. M, Wevers, R. A

“…Context and Objective: Pheochromocytomas and paragangliomas (PGLs) are neuroendocrine tumors of sympathetic or parasympathetic paraganglia. Nearly 40% of PGLs…”
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Association between High Levels of Blood Macrophage Migration Inhibitory Factor, Inappropriate Adrenal Response, and Early Death in Patients with Severe Sepsis by Emonts, Marieke, Sweep, Fred C. G. J., Grebenchtchikov, Nicolai, Geurts-Moespot, Anneke, Knaup, Marlies, Chanson, Anne Laure, Erard, Veronique, Renner, Pascal, Hermans, Peter W. M., Hazelzet, Jan A., Calandra, Thierry

“…Background.Identification of new therapeutic targets remains an imperative goal to improve the morbidity and mortality associated with severe sepsis and septic…”
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Adjuvant Docetaxel in Node-Negative Breast Cancer Patients: A Randomized Trial of AGO-Breast Study Group, German Breast Group, and EORTC-Pathobiology Group by Thomssen, Christoph, Vetter, Martina, Kantelhardt, Eva J, Meisner, Christoph, Schmidt, Marcus, Martin, Pierre M, Clatot, Florian, Augustin, Doris, Hanf, Volker, Paepke, Daniela, Meinerz, Wolfgang, Hoffmann, Gerald, Wiest, Wolfgang, Sweep, Fred C G J, Schmitt, Manfred, Jänicke, Fritz, Loibl, Sibylle, Minckwitz, Gunter von, Harbeck, Nadia

“…In node-negative breast cancer (NNBC), a high risk of recurrence is determined by clinico-pathological or tumor-biological assessment. Taxanes may improve…”
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Adrenal Steroid Metabolites Accumulating in Congenital Adrenal Hyperplasia Lead to Transactivation of the Glucocorticoid Receptor by Pijnenburg-Kleizen, K. J, Engels, M, Mooij, C. F, Griffin, A, Krone, N, Span, P. N, van Herwaarden, A. E, Sweep, F. C. G. J, Claahsen-van der Grinten, H. L

“…Patients with congenital adrenal hyperplasia (CAH) are often clinically less severely affected by cortisol deficiency than anticipated from their enzymatic…”
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Empathic accuracy and oxytocin after tryptophan depletion in adults at risk for depression by Hogenelst, Koen, Schoevers, Robert A., Kema, Ido P., Sweep, Fred C. G. J., aan het Rot, Marije

“…Rationale Major depressive disorder (MDD) has been associated with disturbances in social functioning and in the brain serotonin system. Reduced levels of…”
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Tamoxifen induces radioresistance through NRF2-mediated metabolic reprogramming in breast cancer by Reinema, F V, Sweep, F C G J, Adema, G J, Peeters, W J M, Martens, J W M, Bussink, J, Span, P N

“…Recently, we reported that tamoxifen-resistant (TAM-R) breast cancer cells are cross-resistant to irradiation. Here, we investigated the mechanisms associated…”
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Diffusion-weighted MR imaging in liver metastases of colorectal cancer: reproducibility and biological validation by Heijmen, Linda, ter Voert, Edwin E. G. W., Nagtegaal, Iris D., Span, Paul, Bussink, Johan, Punt, Cornelis J. A., de Wilt, Johannes H. W., Sweep, Fred C. G. J., Heerschap, Arend, van Laarhoven, Hanneke W. M.

“…Objectives Before diffusion-weighted imaging (DWI) can be implemented in standard clinical practice for response monitoring, data on reproducibility are needed…”
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Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones by Dankers, Anita C. A, Sweep, Fred C. G. J, Pertijs, Jeanne C. L. M, Verweij, Vivienne, van den Heuvel, Jeroen J. M. W, Koenderink, Jan B, Russel, Frans G. M, Masereeuw, Rosalinde

“…Breast cancer resistance protein (BCRP) is known for its protective function against the toxic effects of exogenous compounds. In addition to this, a role in…”
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