Search Results - "Swartz, Darl R"

Influence of salt and pyrophosphate on bovine fast and slow myosin S1 dissociation from actin by Shen, Qingwu W., Swartz, Darl R.

“…The kinetics of myosin dissociation from actin was investigated and also the impact of salt, MgPPi, and myosin heavy chain isoform on myosin subfragment 1 (S1)…”
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Measurement of calcium dissociation rates from troponin C in rigor skeletal myofibrils by Little, Sean C, Tikunova, Svetlana B, Norman, Catalina, Swartz, Darl R, Davis, Jonathan P

“…Ca2+ dissociation from the regulatory domain of troponin C may influence the rate of striated muscle relaxation. However, Ca(2+) dissociation from troponin C…”
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Different actions of salt and pyrophosphate on protein extraction from myofibrils reveal the mechanism controlling myosin dissociation by Shen, Qingwu W, Swartz, Darl R, Wang, Zhenyu, Liu, Yue, Gao, Yuan, Zhang, Dequan

“…BACKGROUND Myosin is the major functional protein in muscle foods for water retention, protein binding/gelation and fat holding/emulsification. To maximize its…”
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Different actions of salt and pyrophosphate on protein extraction from myofibrils reveal the mechanism controlling myosin dissociation by Shen, Qingwu W, Swartz, Darl R, Wang, Zhenyu, Liu, Yue, Gao, Yuan, Zhang, Dequan

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Effects of Thin and Thick Filament Proteins on Calcium Binding and Exchange with Cardiac Troponin C by Davis, Jonathan P., Norman, Catalina, Kobayashi, Tomoyoshi, Solaro, R. John, Swartz, Darl R., Tikunova, Svetlana B.

“…Understanding the effects of thin and thick filament proteins on the kinetics of Ca 2+ exchange with cardiac troponin C is essential to elucidating the Ca…”
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Strong binding of myosin increases shortening velocity of rabbit skinned skeletal muscle fibres at low levels of Ca2 by Swartz, Darl R., Moss, Richard L.

“…At low levels of activation, unloaded shortening of skinned skeletal muscle fibres takes place in two phases: an initial phase of high-velocity shortening…”
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Effect of Calcium-Sensitizing Mutations on Calcium Binding and Exchange with Troponin C in Increasingly Complex Biochemical Systems by Tikunova, Svetlana B, Liu, Bin, Swindle, Nicholas, Little, Sean C, Gomes, Aldrin V, Swartz, Darl R, Davis, Jonathan P

“…The calcium-dependent interactions between troponin C (TnC) and other thin and thick filament proteins play a key role in the regulation of cardiac muscle…”
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Effect of Hypertrophic Cardiomyopathy-Linked Troponin C Mutations on the Response of Reconstituted Thin Filaments to Calcium upon Troponin I Phosphorylation by Albury, Acchia N. J, Swindle, Nicholas, Swartz, Darl R, Tikunova, Svetlana B

“…The objective of this work was to investigate the effect of hypertrophic cardiomyopathy-linked A8V and E134D mutations in cardiac troponin C (cTnC) on the…”
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Differences between Cardiac and Skeletal Troponin Interaction with the Thin Filament Probed by Troponin Exchange in Skeletal Myofibrils by Yang, Zhenyun, Yamazaki, Marie, Shen, Qingwu W., Swartz, Darl R.

“…Troponin (Tn) is the calcium-sensing protein of the thin filament. Although cardiac troponin (cTn) and skeletal troponin (sTn) accomplish the same function,…”
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Tripolyphosphate hydrolysis by bovine fast and slow myosin subfragment 1 isoforms by Yamazaki, Marie, Shen, Qingwu W., Swartz, Darl R.

“…Polyphosphates are used in the meat industry to increase the water holding capacity of meat products. Tripolyphosphate (TPP) is a commonly used polyphosphate…”
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A kinetic model of troponin dissociation in relation to thin filament regulation in striated muscle by Sen, Asok K., Swartz, Darl R., Gawalapu, Ravi K.

“…► Effect of troponin dissociation on thin filament regulation in striated muscle is examined. ► A kinetic model is developed to explain the Tn dissociation…”
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Fast Pressure Jumps Can Perturb Calcium and Magnesium Binding to Troponin C F29W by Pearson, David S, Swartz, Darl R, Geeves, Michael A

“…We have used rapid pressure jump and stopped-flow fluorometry to investigate calcium and magnesium binding to F29W chicken skeletal troponin C. Increased…”
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Rho-Kinase Activation Is Involved in Hypoxia-Induced Pulmonary Vasoconstriction by Wang, Zhiqian, Jin, Najia, Ganguli, Supriya, Swartz, Darl R, Li, Liang, Rhoades, Rodney A

“…Rho-associated serine/threonine kinase (Rho-kinase) is a downstream effector of small GTPase RhoA that has recently been shown to play an important role in…”
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Adherens junction-associated protein distribution differs in smooth muscle tissue and acutely isolated cells by Eddinger, Thomas J, Schiebout, Jessen D, Swartz, Darl R

“…This study was designed to examine how smooth muscle (SM) cell (SMC) isolation affects the distribution of some adherens junction (AJ) complex-associated…”
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Effect of Ca2+ binding properties of troponin C on rate of skeletal muscle force redevelopment by Lee, Ryan S, Tikunova, Svetlana B, Kline, Kristopher P, Zot, Henry G, Hasbun, Javier E, Minh, Nguyen Van, Swartz, Darl R, Rall, Jack A, Davis, Jonathan P

“…To investigate effects of altering troponin (Tn)C Ca(2+) binding properties on rate of skeletal muscle contraction, we generated three mutant TnCs with…”
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Myofibrillar Troponin Exists in Three States and there Is Signal Transduction along Skeletal Myofibrillar Thin Filaments by Swartz, Darl R., Yang, Zhenyun, Sen, Asok, Tikunova, Svetlana B., Davis, Jonathan P.

“…Activation of striated muscle contraction is a highly cooperative signal transduction process converting calcium binding by troponin C (TnC) into interactions…”
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Hypoxia Activates Jun-N-Terminal Kinase, Extracellular Signal-Regulated Protein Kinase, and p38 Kinase in Pulmonary Arteries by Jin, Najia, Hatton, Nathan, Swartz, Darl R, Xia, Xiao-ling, Harrington, Maureen A, Larsen, Steven H, Rhoades, Rodney A

“…Chronic alveolar hypoxia is the major cause of pulmonary hypertension. The cellular mechanisms involved in hypoxia- induced pulmonary arterial remodeling are…”
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Smooth muscle adherens junctions associated proteins are stable at the cell periphery during relaxation and activation by Eddinger, Thomas J, Schiebout, Jessen D, Swartz, Darl R

“…This study was performed to determine the stability of the adherens junction (AJ)-associated proteins at the smooth muscle cell (SMC) plasma membrane during…”
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Regulation of Force Development Studied by Photolysis of Caged ADP in Rabbit Skinned Psoas Fibers by Lu, Zhe, Swartz, Darl R., Metzger, Joseph M., Moss, Richard L., Walker, Jeffery W.

“…The present study examined the effects of Ca 2+ and strongly bound cross-bridges on tension development induced by changes in the concentration of MgADP…”
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Unloaded shortening velocity in single permeabilized vascular smooth muscle cells is independent of microtubule status by Zhang, Dahua, Sherwood, Jennifer, Li, Liang, Swartz, Darl R

“…Microtubules may influence smooth muscle contraction either via involvement in signal transduction processes or by serving as an internal load that opposes…”
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