Search Results - "Swart, Karin M.A"
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Feasibility of using head and neck CT imaging to assess skeletal muscle mass in head and neck cancer patients
Published in Oral oncology (01-11-2016)“…Highlights • Sarcopenia, or muscle mass depletion, predicts adverse outcome in cancer patients. • HNC patients have a high prevalence of sarcopenia. • Skeletal…”
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Folic Acid and Vitamin B12 Supplementation and the Risk of Cancer: Long-term Follow-up of the B Vitamins for the Prevention of Osteoporotic Fractures (B-PROOF) Trial
Published in Cancer epidemiology, biomarkers & prevention (01-02-2019)“…Folic acid and vitamin B12 play key roles in one-carbon metabolism. Disruption of one-carbon metabolism may be involved in the risk of cancer. Our aim was to…”
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Effects of 2-year vitamin B12 and folic acid supplementation in hyperhomocysteinemic elderly on arterial stiffness and cardiovascular outcomes within the B-PROOF trial
Published in Journal of hypertension (01-09-2015)“…INTRODUCTION:Hyperhomocysteinemia is an important cardiovascular risk indicator in the oldest old, and is associated with elevated arterial stiffness in this…”
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Results of 2-year vitamin B treatment on cognitive performance: Secondary data from an RCT
Published in Neurology (02-12-2014)“…OBJECTIVE:We investigated the effects of 2-year folic acid and vitamin B12 supplementation on cognitive performance in elderly people with elevated…”
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Type 2 Diabetes, the Epidemic: Trends in Prevalence and Incidence, 2004-2020
Published in Diabetes, metabolic syndrome and obesity (01-01-2024)“…Only a few studies reported the incidence of type 2 diabetes (T2D). Understanding recent trends in diabetes is vital for planning future diabetes care. This…”
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Completeness and Representativeness of the PHARMO General Practitioner (GP) Data: A Comparison with National Statistics
Published in Clinical epidemiology (01-01-2023)“…When using incomplete or non-representative real-world data (RWD), bias is more likely to occur. The aim of the current study was to assess the completeness…”
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Effect of Genetically Low 25-Hydroxyvitamin D on Mortality Risk: Mendelian Randomization Analysis in 3 Large European Cohorts
Published in Nutrients (01-01-2019)“…The aim of this study was to determine if increased mortality associated with low levels of serum 25-hydroxyvitamin D (25(OH)D) reflects a causal relationship…”
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Beta‐blocker use and fall risk in older individuals: Original results from two studies with meta‐analysis
Published in British journal of clinical pharmacology (01-10-2017)“…Aims To investigate the association between use of β‐blockers and β‐blocker characteristics – selectivity, lipid solubility, intrinsic sympathetic activity…”
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The association between apathy, decline in physical performance, and falls in older persons
Published in Aging clinical and experimental research (01-10-2019)“…Background Symptoms of apathy are common in older persons. Negative effects on physical performance and fall risk are plausible, considering the…”
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CYP2C9 Genotypes Modify Benzodiazepine-Related Fall Risk: Original Results From Three Studies With Meta-Analysis
Published in Journal of the American Medical Directors Association (01-01-2017)“…Abstract Objective To investigate whether the CYP2C9*2 and *3 variants modify benzodiazepine-related fall risk. Design Three prospective studies; the Rotterdam…”
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Cognitive Performance: A Cross-Sectional Study on Serum Vitamin D and Its Interplay With Glucose Homeostasis in Dutch Older Adults
Published in Journal of the American Medical Directors Association (01-07-2015)“…Abstract Objectives First, the association between serum 25-hydroxyvitamin D (25[OH]D) and cognitive performance was examined. Second, we assessed whether…”
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Homocysteine level is associated with aortic stiffness in elderly: cross-sectional results from the B-PROOF study
Published in Journal of hypertension (01-05-2013)“…OBJECTIVE:Homocysteine has been shown to be a more accurate predictor of cardiovascular mortality in very old persons than models based on classical risk…”
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Using real‐world general practitioner data to study the diagnosis and management of dementia: rationale and design
Published in Alzheimer's & dementia (01-12-2023)“…Background General practitioners (GPs) play a critical role in the early recognition of cognitive deficits and management of dementia. Timely diagnosis is…”
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Completeness and Representativeness of the PHARMO General Practitioner
Published in Clinical epidemiology (31-01-2023)“…Purpose: When using incomplete or non-representative real-world data (RWD), bias is more likely to occur. The aim of the current study was to assess the…”
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Associations of Clinical Characteristics With Sudden Cardiac Arrest in People With Type 2 Diabetes With and Without Cardiovascular Disease: A Longitudinal Case-Control Study Using Routine Primary Care Data
Published in Diabetes care (18-11-2024)“…To assess longitudinal associations with sudden cardiac arrest (SCA) of clinical characteristics recorded in primary care in people with type 2 diabetes (T2D),…”
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The yield of routine laboratory examination in osteoporosis evaluation in primary care
Published in Osteoporosis international (01-05-2024)“…Summary This study evaluated the yield of routine laboratory examination in a large population of older women in primary care. The prevalence of laboratory…”
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The Effect of a Screening and Treatment Program for the Prevention of Fractures in Older Women: A Randomized Pragmatic Trial
Published in Journal of bone and mineral research (01-11-2019)“…ABSTRACT Population screening for fracture risk may reduce the fracture incidence. In this randomized pragmatic trial, the SALT Osteoporosis Study (SOS), we…”
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Effects of vitamin D supplementation on markers for cardiovascular disease and type 2 diabetes: an individual participant data meta-analysis of randomized controlled trials
Published in The American journal of clinical nutrition (01-06-2018)“…Evidence from randomized controlled trials (RCTs) for the causal role of vitamin D on noncommunicable disease outcomes is inconclusive. The aim of this study…”
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GPs' awareness of pregnancy: trends and association with hazardous medication use
Published in British journal of general practice (01-07-2023)“…GPs have been shown to be important providers of medical care during pregnancy, however, little evidence exists on their awareness of pregnancy when…”
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A meta-analysis of previous falls and subsequent fracture risk in cohort studies
Published in Osteoporosis international (01-03-2024)“…Summary The relationship between self-reported falls and fracture risk was estimated in an international meta-analysis of individual-level data from 46…”
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