Search Results - "Swapna, G. V. T."

microscale protein NMR sample screening pipeline by Rossi, Paolo, Swapna, G. V. T, Huang, Yuanpeng J, Aramini, James M, Anklin, Clemens, Conover, Kenith, Hamilton, Keith, Xiao, Rong, Acton, Thomas B, Ertekin, Asli, Everett, John K, Montelione, Gaetano T

“…As part of efforts to develop improved methods for NMR protein sample preparation and structure determination, the Northeast Structural Genomics Consortium…”
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Structure of Antibacterial Peptide Microcin J25:  A 21-Residue Lariat Protoknot by Bayro, Marvin J, Mukhopadhyay, Jayanta, Swapna, G. V. T, Huang, Janet Y, Ma, Li-Chung, Sineva, Elena, Dawson, Philip E, Montelione, Gaetano T, Ebright, Richard H

“…The antibacterial peptide microcin J25 (MccJ25) inhibits bacterial transcription by binding within, and obstructing, the nucleotide-uptake channel of bacterial…”
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Minimal Heterochiral de Novo Designed 4Fe–4S Binding Peptide Capable of Robust Electron Transfer by Kim, J. Dongun, Pike, Douglas H, Tyryshkin, Alexei M, Swapna, G. V. T, Raanan, Hagai, Montelione, Gaetano T, Nanda, Vikas, Falkowski, Paul G

“…Ambidoxin is a designed, minimal dodecapeptide consisting of alternating L and D amino acids that binds a 4Fe–4S cluster through ligand–metal interactions and…”
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Structural Basis by Which the N‑Terminal Polypeptide Segment of Rhizopus chinensis Lipase Regulates Its Substrate Binding Affinity by Zhang, Meng, Yu, Xiao-Wei, Xu, Yan, Guo, Rey-Ting, Swapna, G. V. T, Szyperski, Thomas, Hunt, John F, Montelione, Gaetano T

“…Members of an important group of industrial enzymes, Rhizopus lipases, exhibit valuable hydrolytic features that underlie their biological functions…”
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Aspirin's Active Metabolite Salicylic Acid Targets High Mobility Group Box 1 to Modulate Inflammatory Responses by Choi, Hyong Woo, Tian, Miaoying, Song, Fei, Venereau, Emilie, Preti, Alessandro, Park, Sang-Wook, Hamilton, Keith, Swapna, G V T, Manohar, Murli, Moreau, Magali, Agresti, Alessandra, Gorzanelli, Andrea, De Marchis, Francesco, Wang, Huang, Antonyak, Marc, Micikas, Robert J, Gentile, Daniel R, Cerione, Richard A, Schroeder, Frank C, Montelione, Gaetano T, Bianchi, Marco E, Klessig, Daniel F

“…Salicylic acid (SA) and its derivatives have been used for millennia to reduce pain, fever and inflammation. In addition, prophylactic use of acetylsalicylic…”
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Cold-shock induced high-yield protein production in Escherichia coli by Inouye, Masayori, Qing, Guoliang, Ma, Li-Chung, Khorchid, Ahmad, Swapna, G V T, Mal, Tapas K, Takayama, Masanori Mitta, Xia, Bing, Phadtare, Sangita, Ke, Haiping, Acton, Thomas, Montelione, Gaetano T, Ikura, Mitsuhiko

“…Overexpression of proteins in Escherichia coli at low temperature improves their solubility and stability. Here, we apply the unique features of the cspA gene…”
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Engineering of a wheat germ expression system to provide compatibility with a high throughput pET-based cloning platform by Zhao, Li, Zhao, Kate Q, Hurst, Robin, Slater, Michael R, Acton, Thomas B, Swapna, G. V. T, Shastry, Ritu, Kornhaber, Gregory J, Montelione, Gaetano T

“…Wheat germ cell-free methods provide an important approach for the production of eukaryotic proteins. We have developed a protein expression vector for the…”
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Conserved Surface Features Form the Double-stranded RNA Binding Site of Non-structural Protein 1 (NS1) from Influenza A and B Viruses by Yin, Cuifeng, Khan, Javed A., Swapna, G.V.T., Ertekin, Asli, Krug, Robert M., Tong, Liang, Montelione, Gaetano T.

“…Influenza A viruses cause a highly contagious respiratory disease in humans and are responsible for periodic widespread epidemics with high mortality rates…”
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Efficient production of 2H, 13C, 15N-enriched industrial enzyme Rhizopus chinensis lipase with native disulfide bonds by Zhang, Meng, Yu, Xiao-Wei, Swapna, G. V. T, Xiao, Rong, Zheng, Haiyan, Sha, Chong, Xu, Yan, Montelione, Gaetano T

“…In order to use most modern methods of NMR spectroscopy to study protein structure and dynamics, isotope-enriched protein samples are essential. Especially for…”
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Segmental isotope labeling of proteins for NMR structural study using a protein S tag for higher expression and solubility by Kobayashi, Hiroshi, Swapna, G. V. T., Wu, Kuen-Phon, Afinogenova, Yuliya, Conover, Kenith, Mao, Binchen, Montelione, Gaetano T., Inouye, Masayori

“…A common obstacle to NMR studies of proteins is sample preparation. In many cases, proteins targeted for NMR studies are poorly expressed and/or expressed in…”
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Solution NMR and X-ray crystal structures of membrane-associated Lipoprotein-17 domain reveal a novel fold by Mani, Rajeswari, Vorobiev, Sergey, Swapna, G. V. T., Neely, Helen, Janjua, Haleema, Ciccosanti, Colleen, Xiao, Rong, Acton, Thomas B., Everett, John K., Hunt, John, Montelione, Gaetano T.

“…The conserved Lipoprotein-17 domain of membrane-associated protein Q9PRA0_UREPA from Ureaplasma parvum was selected for structure determination by the…”
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Principles for designing proteins with cavities formed by curved β sheets by Marcos, Enrique, Basanta, Benjamin, Chidyausiku, Tamuka M., Tang, Yuefeng, Oberdorfer, Gustav, Liu, Gaohua, Swapna, G. V. T., Guan, Rongjin, Silva, Daniel-Adriano, Dou, Jiayi, Pereira, Jose Henrique, Xiao, Rong, Sankaran, Banumathi, Zwart, Peter H., Montelione, Gaetano T., Baker, David

“…Active sites and ligand-binding cavities in native proteins are often formed by curved β sheets, and the ability to control β-sheet curvature would allow…”
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Comparisons of NMR Spectral Quality and Success in Crystallization Demonstrate that NMR and X-ray Crystallography Are Complementary Methods for Small Protein Structure Determination by Snyder, David A, Chen, Yang, Denissova, Natalia G, Acton, Thomas, Aramini, James M, Ciano, Melissa, Karlin, Richard, Liu, Jinfeng, Manor, Philip, Rajan, P. A, Rossi, Paolo, Swapna, G. V. T, Xiao, Rong, Rost, Burkhard, Hunt, John, Montelione, Gaetano T

“…X-ray crystallography and NMR spectroscopy provide the only sources of experimental data from which protein structures can be analyzed at high or even atomic…”
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Assessment of prediction methods for protein structures determined by NMR in CASP14: Impact of AlphaFold2 by Huang, Yuanpeng Janet, Zhang, Ning, Bersch, Beate, Fidelis, Krzysztof, Inouye, Masayori, Ishida, Yojiro, Kryshtafovych, Andriy, Kobayashi, Naohiro, Kuroda, Yutaka, Liu, Gaohua, LiWang, Andy, Swapna, G.V.T, Wu, Nan, Yamazaki, Toshio, Montelione, Gaetano T.

“…NMR studies can provide unique information about protein conformations in solution. In CASP14, three reference structures provided by solution NMR methods were…”
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Effect of mitochondrial uncouplers niclosamide ethanolamine (NEN) and oxyclozanide on hepatic metastasis of colon cancer by Alasadi, Amer, Chen, Michael, Swapna, G. V. T., Tao, Hanlin, Guo, Jingjing, Collantes, Juan, Fadhil, Noor, Montelione, Gaetano T., Jin, Shengkan

“…Metabolism of cancer cells is characterized by aerobic glycolysis, or the Warburg effect. Aerobic glycolysis reduces pyruvate flux into mitochondria,…”
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The copBL operon protects Staphylococcus aureus from copper toxicity: CopL is an extracellular membrane–associated copper-binding protein by Rosario-Cruz, Zuelay, Eletsky, Alexander, Daigham, Nourhan S., Al-Tameemi, Hassan, Swapna, G.V.T, Kahn, Peter C., Szyperski, Thomas, Montelione, Gaetano T., Boyd, Jeffrey M.

“…As complications associated with antibiotic resistance have intensified, copper (Cu) is attracting attention as an antimicrobial agent. Recent studies have…”
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A common binding motif in the ET domain of BRD3 forms polymorphic structural interfaces with host and viral proteins by Aiyer, Sriram, Swapna, G.V.T., Ma, Li-Chung, Liu, Gaohua, Hao, Jingzhou, Chalmers, Gordon, Jacobs, Brian C., Montelione, Gaetano T., Roth, Monica J.

“…The extraterminal (ET) domain of BRD3 is conserved among BET proteins (BRD2, BRD3, BRD4), interacting with multiple host and viral protein-protein networks…”
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Structure Determination of Challenging Protein–Peptide Complexes Combining NMR Chemical Shift Data and Molecular Dynamics Simulations by Mondal, Arup, Swapna, G.V.T., Lopez, Maria M., Klang, Laura, Hao, Jingzhou, Ma, LiChung, Roth, Monica J., Montelione, Gaetano T., Perez, Alberto

“…Intrinsically disordered regions of proteins often mediate important protein–protein interactions. However, the folding-upon-binding nature of many…”
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1H, 13C, and 15N resonance assignments for Escherichia coli ytfP, a member of the broadly conserved UPF0131 protein domain family by Aramini, James M, Swapna, G V T, Huang, Yuanpeng J, Rajan, P K, Xiao, Rong, Shastry, Ritu, Acton, Thomas B, Cort, John R, Kennedy, Michael A, Montelione, Gaetano T

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Protein structure prediction assisted with sparse NMR data in CASP13 by Sala, Davide, Huang, Yuanpeng Janet, Cole, Casey A., Snyder, David A., Liu, Gaohua, Ishida, Yojiro, Swapna, G.V.T., Brock, Kelly P., Sander, Chris, Fidelis, Krzysztof, Kryshtafovych, Andriy, Inouye, Masayori, Tejero, Roberto, Valafar, Homayoun, Rosato, Antonio, Montelione, Gaetano T.

“…CASP13 has investigated the impact of sparse NMR data on the accuracy of protein structure prediction. NOESY and 15N‐1H residual dipolar coupling data, typical…”
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