Search Results - "Swanton, J G"
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The effect of three H2-receptor antagonists on the disposition of midazolam in the rat in-situ perfused liver model
Published in Journal of pharmacy and pharmacology (01-12-1994)“…The rat in-situ perfused liver model was used to investigate the effect of three H2-receptor antagonists on the pharmacokinetic disposition of the short-acting…”
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The effect of three H2 receptor antagonists on the disposition of cyclosporin A in the in situ perfused rat liver model
Published in Biopharmaceutics & drug disposition (01-12-1995)“…The in situ perfused rat liver model was used to investigate the effect of three H2 receptor antagonists on the disposition of cyclosporin A (CyA) and the…”
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Cyclosporin A and erythromycin: a study of a drug interaction in the in situ perfused rat liver model
Published in Biopharmaceutics & drug disposition (01-10-1993)“…Using the in situ perfused rat liver model, the effect of erythromycin (Ery) on the disposition of cyclosporin A (CyA) and the major human metabolite, AM1, was…”
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In situ liver perfusion techniques: the significance of the anaesthetic procedure used
Published in European journal of drug metabolism and pharmacokinetics (1988)“…Pentobarbitone may not be an appropriate anaesthetic to use on the donor rat of an isolated liver perfusion model intended to study drug-drug interactions,…”
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The cardio‐toxicity of isoprenaline during hypoxia
Published in British journal of pharmacology (01-05-1969)“…1 The effects of the intravenous injection of isoprenaline on heart rate and arterial pressure has been studied in dogs artificially respired with room air or…”
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FURTHER OBSERVATIONS ON THE CARDIOTOXICITY OF ISOPRENALINE DURING HYPOXIA
Published in British journal of pharmacology (01-03-1974)“…1 In dogs respired with 10% oxygen: 90% nitrogen, only five out of 16 dogs survived repeated intravenous doses of isoprenaline (either 0.5 or 1.0 μg/kg) and…”
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An assessment of the suitability of a modified technique of in situ rat-liver perfusion for the study of certain hepatic drug-drug interactions
Published in Journal of pharmacological methods (01-12-1984)“…A modified technique of in situ rat-liver perfusion has been developed. Minor modifications were made for practical purposes to an existing technique…”
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Digoxin distribution between plasma and myocardium in hypoxic and non-hypoxic dogs
Published in Experientia (15-07-1982)Get full text
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The influence of hypoxia and hypercapnia on the cardiotoxicity of isoprenaline in dogs [proceedings]
Published in Journal of pharmacy and pharmacology (01-12-1978)Get more information
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The influence of arterial pH control on the cardiotoxicity of isoprenaline in hypoxic dogs [proceedings]
Published in Journal of pharmacy and pharmacology (01-12-1979)Get more information
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Digoxin plasma and myocardial level correlation in hypoxic dogs [proceedings]
Published in Journal of pharmacy and pharmacology (01-12-1978)Get more information
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