Search Results - "Swanson, W Benton"
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Novel approaches for periodontal tissue engineering
Published in Genesis (New York, N.Y. : 2000) (01-09-2022)“…Summary The periodontal complex involves the hard and soft tissues which support dentition, comprised of cementum, bone, and the periodontal ligament (PDL)…”
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Pore size directs bone marrow stromal cell fate and tissue regeneration in nanofibrous macroporous scaffolds by mediating vascularization
Published in Acta biomaterialia (01-12-2018)“…[Display omitted] In the U.S., 30% of adults suffer joint pain, most commonly in the knee, which severely limits mobility and is often attributed to injury of…”
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New paradigms in regenerative engineering: Emerging role of extracellular vesicles paired with instructive biomaterials
Published in Biocell (2022)“…Mesenchymal stem cells (MSCs) have long been regarded as critical components of regenerative medicine strategies, given their multipotency and persistence in a…”
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Mechanobiology-informed biomaterial and tissue engineering strategies for influencing skeletal stem and progenitor cell fate
Published in Frontiers in physiology (13-07-2023)“…Skeletal stem and progenitor cells (SSPCs) are the multi-potent, self-renewing cell lineages that form the hematopoietic environment and adventitial structures…”
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Infection-free rates and Sequelae predict factors in bone transportation for infected tibia: a systematic review and meta-analysis
Published in BMC musculoskeletal disorders (13-12-2018)“…Tibia infected nonunion and chronic osteomyelitis are challenging clinical presentations. Bone transportation with external or hybrid fixators (combined…”
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Scaffold Pore Curvature Influences ΜSC Fate through Differential Cellular Organization and YAP/TAZ Activity
Published in International journal of molecular sciences (19-04-2022)“…Tissue engineering aims to repair, restore, and/or replace tissues in the human body as an alternative to grafts and prostheses. Biomaterial scaffolds can be…”
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Platform technologies for regenerative endodontics from multifunctional biomaterials to tooth-on-a-chip strategies
Published in Clinical oral investigations (01-08-2021)“…Objectives The aim of this review is to highlight recent progress in the field of biomaterials-mediated dental pulp tissue engineering. Specifically, we aim to…”
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Rapamycin rescues BMP mediated midline craniosynostosis phenotype through reduction of mTOR signaling in a mouse model
Published in Genesis (New York, N.Y. : 2000) (01-06-2018)“…Summary Craniosynostosis is defined as congenital premature fusion of one or more cranial sutures. While the genetic basis for about 30% of cases is known, the…”
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Temperature-responsive PCL-PLLA nanofibrous tissue engineering scaffolds with memorized porous microstructure recovery
Published in Frontiers in dental medicine (2023)“…Biomaterial scaffolds in tissue engineering facilitate tissue regeneration and integration with the host. Poor healing outcomes arise from lack of cell and…”
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Scaffolds with controlled release of pro-mineralization exosomes to promote craniofacial bone healing without cell transplantation
Published in Acta biomaterialia (01-12-2020)“…Biomimetic bone regeneration methods which demonstrate both clinical and manufacturing feasibility, as alternatives to autogenic or allogenic bone grafting,…”
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Controlled release of odontogenic exosomes from a biodegradable vehicle mediates dentinogenesis as a novel biomimetic pulp capping therapy
Published in Journal of controlled release (10-08-2020)“…Mineralized enamel and dentin provide protection to the dental pulp, which is vital tissue rich with cells, vasculature, and nerves in the inner tooth. Dental…”
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Macropore design of tissue engineering scaffolds regulates mesenchymal stem cell differentiation fate
Published in Biomaterials (01-05-2021)“…Craniosynostosis is a debilitating birth defect characterized by the premature fusion of cranial bones resulting from premature loss of stem cells located in…”
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Three-Dimensional Electrodeposition of Calcium Phosphates on Porous Nanofibrous Scaffolds and Their Controlled Release of Calcium for Bone Regeneration
Published in ACS applied materials & interfaces (22-07-2020)“…To mimic the bone matrix of mineralized collagen and to impart microporous structure to facilitate cell migration and bone regeneration, we developed a…”
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Next-generation biomaterials for dental pulp tissue immunomodulation
Published in Dental materials (01-04-2023)“…The current standard for treating irreversibly damaged dental pulp is root canal therapy, which involves complete removal and debridement of the pulp space and…”
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Methacrylated Gelatin as an On-Demand Injectable Vehicle for Drug Delivery in Dentistry
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Gelatin methacrylate (GelMA) is a biodegradable and biocompatible engineered material with significant promise for its applications in tissue engineering, drug…”
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Amino Acid-Based Poly(ester urea) Biodegradable Membrane for Guided Bone Regeneration
Published in ACS applied materials & interfaces (09-10-2024)“…Barrier membranes (BM) for guided bone regeneration (GBR) aim to support the osteogenic healing process of a defined bony defect by excluding epithelial…”
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The future of cell-instructive biomaterials for tissue regeneration–a perspective from early career clinician-scientists
Published in Frontiers in materials (16-01-2024)“…Cell-instructive biomaterials are an essential component in tissue engineering and regenerative medicine. In the past three decades since the term “Tissue…”
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Integration of Melt Electrowritten Polymeric Scaffolds and Bioprinting for Epithelial Healing via Localized Periostin Delivery
Published in ACS macro letters (20-08-2024)“…Management of skin injuries imposes a substantial financial burden on patients and hospitals, leading to diminished quality of life. Periostin (rhOSF), an…”
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Synthetic Periodontal Guided Tissue Regeneration Membrane with Self-Assembling Biphasic Structure and Temperature-Sensitive Shape Maintenance
Published in Advanced healthcare materials (23-10-2024)“…Periodontal disease poses significant challenges to the long-term stability of oral health by destroying the supporting structures of teeth. Guided tissue…”
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A library of Rhodamine6G-based pH-sensitive fluorescent probes with versatile in vivo and in vitro applications
Published in RSC chemical biology (08-06-2022)“…Acidic pH is critical to the function of the gastrointestinal system, bone-resorbing osteoclasts, and the endolysosomal compartment of nearly every cell in the…”
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