Search Results - "Swanson, Selene K."

Serine and SAM Responsive Complex SESAME Regulates Histone Modification Crosstalk by Sensing Cellular Metabolism by Li, Shanshan, Swanson, Selene K., Gogol, Madelaine, Florens, Laurence, Washburn, Michael P., Workman, Jerry L., Suganuma, Tamaki

“…Pyruvate kinase M2 (PKM2) is a key enzyme for glycolysis and catalyzes the conversion of phosphoenolpyruvate (PEP) to pyruvate, which supplies cellular energy…”
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Human Mediator Subunit MED26 Functions as a Docking Site for Transcription Elongation Factors by Takahashi, Hidehisa, Parmely, Tari J., Sato, Shigeo, Tomomori-Sato, Chieri, Banks, Charles A.S., Kong, Stephanie E., Szutorisz, Henrietta, Swanson, Selene K., Martin-Brown, Skylar, Washburn, Michael P., Florens, Laurence, Seidel, Chris W., Lin, Chengqi, Smith, Edwin R., Shilatifard, Ali, Conaway, Ronald C., Conaway, Joan W.

“…Promoter-proximal pausing by initiated RNA polymerase II (Pol II) and regulated release of paused polymerase into productive elongation has emerged as a major…”
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Histone H3 lysine-to-methionine mutants as a paradigm to study chromatin signaling by Herz, Hans-Martin, Morgan, Marc, Gao, Xin, Jackson, Jessica, Rickels, Ryan, Swanson, Selene K., Florens, Laurence, Washburn, Michael P., Eissenberg, Joel C., Shilatifard, Ali

“…Histone H3 lysine27-to-methionine (H3K27M) gain-of-function mutations occur in highly aggressive pediatric gliomas. We established a Drosophila animal model…”
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DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly by Litovchick, Larisa, Florens, Laurence A, Swanson, Selene K, Washburn, Michael P, DeCaprio, James A

“…In the absence of growth signals, cells exit the cell cycle and enter into G0 or quiescence. Alternatively, cells enter senescence in response to inappropriate…”
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Zic2 Is an Enhancer-Binding Factor Required for Embryonic Stem Cell Specification by Luo, Zhuojuan, Gao, Xin, Lin, Chengqi, Smith, Edwin R., Marshall, Stacy A., Swanson, Selene K., Florens, Laurence, Washburn, Michael P., Shilatifard, Ali

“…The Zinc-finger protein of the cerebellum 2 (Zic2) is one of the vertebrate homologs of the Drosophila pair-rule gene odd-paired (opa). Our molecular and…”
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The human cytoplasmic dynein interactome reveals novel activators of motility by Redwine, William B, DeSantis, Morgan E, Hollyer, Ian, Htet, Zaw Min, Tran, Phuoc Tien, Swanson, Selene K, Florens, Laurence, Washburn, Michael P, Reck-Peterson, Samara L

“…In human cells, cytoplasmic dynein-1 is essential for long-distance transport of many cargos, including organelles, RNAs, proteins, and viruses, towards…”
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Comprehensive Spatial Analysis of the Borrelia burgdorferi Lipoproteome Reveals a Compartmentalization Bias toward the Bacterial Surface by Dowdell, Alexander S, Murphy, Maxwell D, Azodi, Christina, Swanson, Selene K, Florens, Laurence, Chen, Shiyong, Zückert, Wolfram R

“…The Lyme disease spirochete is unique among bacteria in its large number of lipoproteins that are encoded by a small, exceptionally fragmented, and…”
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Poly(ADP-ribosyl)ation directs recruitment and activation of an ATP-dependent chromatin remodeler by Gottschalk, Aaron J, Timinszky, Gyula, Kong, Stephanie E, Jin, Jingji, Cai, Yong, Swanson, Selene K, Washburn, Michael P, Florens, Laurence, Ladurner, Andreas G, Conaway, Joan W, Conaway, Ronald C

“…Posttranslational modifications play a key role in recruiting chromatin remodeling and modifying enzymes to specific regions of chromosomes to modulate…”
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Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis by Cheng, Jingwei, Park, Donglim Esther, Berrios, Christian, White, Elizabeth A, Arora, Reety, Yoon, Rosa, Branigan, Timothy, Xiao, Tengfei, Westerling, Thomas, Federation, Alexander, Zeid, Rhamy, Strober, Benjamin, Swanson, Selene K, Florens, Laurence, Bradner, James E, Brown, Myles, Howley, Peter M, Padi, Megha, Washburn, Michael P, DeCaprio, James A

“…Merkel cell carcinoma (MCC) frequently contains integrated copies of Merkel cell polyomavirus DNA that express a truncated form of Large T antigen (LT) and an…”
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Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection by Srivastava, Smita, Swanson, Selene K, Manel, Nicolas, Florens, Laurence, Washburn, Michael P, Skowronski, Jacek

“…Vpx is a small virion-associated adaptor protein encoded by viruses of the HIV-2/SIVsm lineage of primate lentiviruses that enables these viruses to transduce…”
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Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex by Cai, Yong, Jin, Jingji, Swanson, Selene K., Cole, Michael D., Choi, Seung Hyuk, Florens, Laurence, Washburn, Michael P., Conaway, Joan W., Conaway, Ronald C.

“…Human MOF (MYST1), a member of the MYST (Moz-Ybf2/Sas3-Sas2-Tip60) family of histone acetyltransferases (HATs), is the human ortholog of the Drosophilamales…”
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The Little Elongation Complex Regulates Small Nuclear RNA Transcription by Smith, Edwin R., Lin, Chengqi, Garrett, Alexander S., Thornton, Janet, Mohaghegh, Nima, Hu, Deqing, Jackson, Jessica, Saraf, Anita, Swanson, Selene K., Seidel, Christopher, Florens, Laurence, Washburn, Michael P., Eissenberg, Joel C., Shilatifard, Ali

“…Eleven-nineteen lysine-rich leukemia (ELL) participates in the super elongation complex (SEC) with the RNA polymerase II (Pol II) CTD kinase P-TEFb. SEC is a…”
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Evolutionarily Conserved Multisubunit RBL2/p130 and E2F4 Protein Complex Represses Human Cell Cycle-Dependent Genes in Quiescence by Litovchick, Larisa, Sadasivam, Subhashini, Florens, Laurence, Zhu, Xiaopeng, Swanson, Selene K., Velmurugan, Soundarapandian, Chen, Runsheng, Washburn, Michael P., Liu, X. Shirley, DeCaprio, James A.

“…The mammalian Retinoblastoma (RB) family including pRB, p107, and p130 represses E2F target genes through mechanisms that are not fully understood. In D…”
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Histone H3 Methylation by Set2 Directs Deacetylation of Coding Regions by Rpd3S to Suppress Spurious Intragenic Transcription by Carrozza, Michael J., Li, Bing, Florens, Laurence, Suganuma, Tamaki, Swanson, Selene K., Lee, Kenneth K., Shia, Wei-Jong, Anderson, Scott, Yates, John, Washburn, Michael P., Workman, Jerry L.

“…Yeast Rpd3 histone deacetylase plays an important role at actively transcribed genes. We characterized two distinct Rpd3 complexes, Rpd3L and Rpd3S, by MudPIT…”
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Scm3 Is Essential to Recruit the Histone H3 Variant Cse4 to Centromeres and to Maintain a Functional Kinetochore by Camahort, Raymond, Li, Bing, Florens, Laurence, Swanson, Selene K., Washburn, Michael P., Gerton, Jennifer L.

“…The kinetochore is a complex multiprotein structure located at centromeres that is essential for proper chromosome segregation. Budding-yeast Cse4 is an…”
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Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics by Sardiu, Mihaela E, Cai, Yong, Jin, Jingji, Swanson, Selene K, Conaway, Ronald C, Conaway, Joan W, Florens, Laurence, Washburn, Michael P

“…Large-scale affinity purification and mass spectrometry studies have played important roles in the assembly and analysis of comprehensive protein interaction…”
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Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes by Lee, Kenneth K, Sardiu, Mihaela E, Swanson, Selene K, Gilmore, Joshua M, Torok, Michael, Grant, Patrick A, Florens, Laurence, Workman, Jerry L, Washburn, Michael P

“…Despite the availability of several large‐scale proteomics studies aiming to identify protein interactions on a global scale, little is known about how…”
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Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling by Oh, Seunghee, Lee, Jaehyoun, Swanson, Selene K, Florens, Laurence, Washburn, Michael P, Workman, Jerry L

“…Changes in available nutrients are inevitable events for most living organisms. Upon nutritional stress, several signaling pathways cooperate to change the…”
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Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle by Hrecka, Kasia, Gierszewska, Magdalena, Srivastava, Smita, Kozaczkiewicz, Lukasz, Swanson, Selene K, Florens, Laurence, Washburn, Michael P, Skowronski, Jacek

“…The replication of viruses depends on the cell cycle status of the infected cells. Viruses have evolved functions that alleviate restrictions imposed on their…”
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Proteasome recruitment and activation of the Uch37 deubiquitinating enzyme by Adrm1 by Conaway, Joan Weliky, Cohen, Robert E, Yao, Tingting, Song, Ling, Xu, Wei, DeMartino, George N, Florens, Laurence, Swanson, Selene K, Washburn, Michael P, Conaway, Ronald C

“…Uch37 is one of the three principal deubiquitinating enzymes (DUBs), and the only ubiquitin carboxy-terminal hydrolase (UCH)-family protease, that is…”
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