Search Results - "Swanson, Garth R."

Binge drinking alcohol and circadian misalignment in night shift nurses is associated with decreased resiliency to COVID‐19 infection by Swanson, Garth R., Schwartz, Benjamin A., Joyce, Cara, Keshavarzian, Ali

“…Background Nurses and other first responders are at high risk of exposure to the SARS‐CoV2 virus, and many have developed severe COVID‐19 infection. A better…”
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Circadian misalignment by environmental light/dark shifting causes circadian disruption in colon by Tran, Laura, Jochum, Sarah B, Shaikh, Maliha, Wilber, Sherry, Zhang, Lijuan, Hayden, Dana M, Forsyth, Christopher B, Voigt, Robin M, Bishehsari, Faraz, Keshavarzian, Ali, Swanson, Garth R

“…Physiological circadian rhythms (CRs) are complex processes with 24-hour oscillations that regulate diverse biological functions. Chronic weekly light/dark…”
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Pattern of alcohol consumption and its effect on gastrointestinal symptoms in inflammatory bowel disease by Swanson, Garth R, Sedghi, Shahriar, Farhadi, Ashkan, Keshavarzian, Ali

“…Abstract Alcohol consumption is a potential trigger for flare in inflammatory bowel disease (IBD) flare because of alcohol's pro-oxidant effects and its…”
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Sleep disturbances and inflammatory bowel disease: a potential trigger for disease flare? by Swanson, Garth R, Burgess, Helen J, Keshavarzian, Ali

“…Inflammatory bowel disease (IBD) is a waxing and waning disease characterized by diarrhea, abdominal pain and weight loss. Recently, there has been an…”
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Alcohol and the Intestine by Patel, Sheena, Behara, Rama, Swanson, Garth R, Forsyth, Christopher B, Voigt, Robin M, Keshavarzian, Ali

“…Alcohol abuse is a significant contributor to the global burden of disease and can lead to tissue damage and organ dysfunction in a subset of alcoholics…”
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Disrupted Circadian Rest-Activity Cycles in Inflammatory Bowel Disease Are Associated With Aggressive Disease Phenotype, Subclinical Inflammation, and Dysbiosis by Swanson, Garth R, Kochman, Nicole, Amin, Jaimin, Chouhan, Vijit, Yim, Wesley, Engen, Phillip A, Shaikh, Maliha, Naqib, Ankur, Tran, Laura, Voigt, Robin M, Forsyth, Christopher B, Green, Stefan J, Keshavarzian, Ali

“…Patients with inflammatory bowel disease (IBD)-Crohn's disease (CD), and ulcerative colitis (UC), have poor sleep quality. Sleep and multiple immunologic and…”
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Evidence that the loss of colonic anti-microbial peptides may promote dysbiotic Gram-negative inflammaging-associated bacteria in aging mice by Forsyth, Christopher B, Shaikh, Maliha, Engen, Phillip A, Preuss, Fabian, Naqib, Ankur, Palmen, Breanna A, Green, Stefan J, Zhang, Lijuan, Bogin, Zlata R, Lawrence, Kristi, Sharma, Deepak, Swanson, Garth R, Bishehsari, Faraz, Voigt, Robin M, Keshavarzian, Ali

“…Aging studies in humans and mice have played a key role in understanding the intestinal microbiome and an increased abundance of "inflammaging" Gram-negative…”
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Disrupted diurnal oscillation of gut-derived Short chain fatty acids in shift workers drinking alcohol: Possible mechanism for loss of resiliency of intestinal barrier in disrupted circadian host by Swanson, Garth R., Siskin, Joel, Gorenz, Annika, Shaikh, Maliha, Raeisi, Shohreh, Fogg, Louis, Forsyth, Christopher, Keshavarzian, Ali

“…Microbiota derived short chain fatty acids (SCFAs) are produced by fermentation of nondigestible fiber, and are a key component in intestinal barrier…”
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Sleep and Circadian Hygiene and Inflammatory Bowel Disease by Swanson, Garth R., Burgess, Helen J.

“…There is increasing evidence that sleep and circadian disruption can worsen the disease course in inflammatory bowel disease (IBD). Sleep and circadian…”
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Increased Intestinal Permeability and Decreased Resiliency of the Intestinal Barrier in Alcoholic Liver Disease by Swanson, Garth R, Garg, Kanika, Shaikh, Maliha, Keshavarzian, Ali

“…Only 20%-30% of individuals with alcohol use disorder (AUD) develop alcoholic liver disease (ALD). While the development of gut-derived endotoxemia is…”
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Alcohol use disorder as a potential risk factor for COVID‐19 severity: A narrative review by Forsyth, Christopher B., Voigt, Robin M., Swanson, Garth R., Bishehsari, Faraz, Shaikh, Maliha, Zhang, Lijuan, Engen, Phillip, Keshavarzian, Ali

“…In Dec. 2019‐January 2020, a pneumonia illness originating in Wuhan, China, designated as coronavirus disease 2019 (COVID‐19) was shown to be caused by a novel…”
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Night workers with circadian misalignment are susceptible to alcohol-induced intestinal hyperpermeability with social drinking by Swanson, Garth R, Gorenz, Annika, Shaikh, Maliha, Desai, Vishal, Kaminsky, Thomas, Van Den Berg, Jolice, Murphy, Terrence, Raeisi, Shohreh, Fogg, Louis, Vitaterna, Martha Hotz, Forsyth, Christopher, Turek, Fred, Burgess, Helen J, Keshavarzian, Ali

“…Alcohol-induced intestinal hyperpermeability (AIHP) is a known risk factor for alcoholic liver disease (ALD), but only 20-30% of heavy alcoholics develop AIHP…”
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Chronotype, social jet lag, sleep debt and food timing in inflammatory bowel disease by Chakradeo, Prachi S., Keshavarzian, Ali, Singh, Shubha, Dera, Akram E., Esteban, James Philip G., Lee, Alice A., Burgess, Helen J., Fogg, Louis, Swanson, Garth R.

“…The preference of the sleep/wake cycle can be grouped into categories or chronotypes. Inflammatory bowel disease (IBD) has been linked to poor sleep quality…”
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Decreased melatonin secretion is associated with increased intestinal permeability and marker of endotoxemia in alcoholics by Swanson, Garth R, Gorenz, Annika, Shaikh, Maliha, Desai, Vishal, Forsyth, Christopher, Fogg, Louis, Burgess, Helen J, Keshavarzian, Ali

“…Chronic heavy alcohol use is known to cause gut leakiness and alcoholic liver disease (ALD), but only 30% of heavy drinkers develop increased intestinal…”
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Colon epithelial cell-specific Bmal1 deletion impairs bone formation in mice by Ko, Frank C., Jochum, Sarah B., Wilson, Brittany M., Adra, Amal, Patel, Nikhil, Lee, Hoomin, Wilber, Sherry, Shaikh, Maliha, Forsyth, Christopher, Keshavarzian, Ali, Swanson, Garth R., Sumner, D. Rick

“…The circadian clock system regulates multiple metabolic processes, including bone metabolism. Previous studies have demonstrated that both central and…”
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Colonic Epithelial Circadian Disruption Worsens Dextran Sulfate Sodium–Induced Colitis by Jochum, Sarah B, Engen, Phillip A, Shaikh, Maliha, Naqib, Ankur, Wilber, Sherry, Raeisi, Shohreh, Zhang, Lijuan, Song, Shiwen, Sanzo, Gabriella, Chouhan, Vijit, Ko, Frank, Post, Zoe, Tran, Laura, Ramirez, Vivian, Green, Stefan J, Khazaie, Khashayarsha, Hayden, Dana M, Brown, Mark J, Voigt, Robin M, Forsyth, Christopher B, Keshavarzian, Ali, Swanson, Garth R

“…Abstract Background Disruption of central circadian rhythms likely mediated by changes in microbiota and a decrease in gut-derived metabolites like short chain…”
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Impact of Chronotherapy on 6-Mercaptopurine Metabolites in Inflammatory Bowel Disease: A Pilot Crossover Trial by Swanson, Garth R., Biglin, Mary, Raff, Hannah, Chouhan, Vijit, Jochum, Sarah, Shaikh, Maliha, Francey, Lauren, Bishehsari, Faraz, Hogenesch, John, Keshavarzian, Ali

“…Chronotherapy is the timing of medication according to biological rhythms of the host to optimize drug efficacy and minimize toxicity. Efficacy and…”
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Circadian rhythms, alcohol and gut interactions by Forsyth, Christopher B, Voigt, Robin M, Burgess, Helen J, Swanson, Garth R, Keshavarzian, Ali

“…Abstract The circadian clock establishes rhythms throughout the body with an approximately 24 hour period that affect expression of hundreds of genes…”
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S781 Colonic Circadian Rhythm Disruption Alters Expression of Short Chain Fatty Acids and Intestinal Receptors in Mice by Post, Zoe, Engen, Philip A., Shaikh, Maliha, Jochum, Sarah B., Wilber, Sherry, Brown, Mark J., Khazaie, Khashavarsha, Hayden, Dana M., Voigt, Robin M., Forsyth, Christopher B., Keshavarzian, Ali, Swanson, Garth R.

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Is moderate red wine consumption safe in inactive inflammatory bowel disease? by Swanson, Garth R, Tieu, Vanessa, Shaikh, Maliha, Forsyth, Chris, Keshavarzian, Ali

“…Alcohol consumption is a potential trigger for inflammatory bowel disease (IBD) flare because of alcohol-induced oxidative stress and its deleterious effects…”
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