Search Results - "Swanson, Carter J."

Viral Aggregation: The Knowns and Unknowns by Pradhan, Swechchha, Varsani, Arvind, Leff, Chloe, Swanson, Carter J, Hariadi, Rizal F

“…Viral aggregation is a complex and pervasive phenomenon affecting many viral families. An increasing number of studies have indicated that it can modulate…”
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The GCaMP‑R Family of Genetically Encoded Ratiometric Calcium Indicators by Cho, Jung-Hwa, Swanson, Carter J, Chen, Jeannie, Li, Ang, Lippert, Lisa G, Boye, Shannon E, Rose, Kasey, Sivaramakrishnan, Sivaraj, Chuong, Cheng-Ming, Chow, Robert H

“…We report on GCaMP-Rs, a new family of genetically encoded ratiometric calcium indicators that extend the virtues of the GCaMP proteins to ratiometric…”
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Calcium Stimulates Self-Assembly of Protein Kinase C α In Vitro by Swanson, Carter J, Sommese, Ruth F, Petersen, Karl J, Ritt, Michael, Karslake, Joshua, Thomas, David D, Sivaramakrishnan, Sivaraj

“…Protein kinase C α (PKCα) is a nodal regulator in several intracellular signaling networks. PKCα is composed of modular domains that interact with each other…”
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Homozygous KSR1 deletion attenuates morbidity but does not prevent tumor development in a mouse model of RAS-driven pancreatic cancer by Germino, Elizabeth A, Miller, Joseph P, Diehl, Lauri, Swanson, Carter J, Durinck, Steffen, Modrusan, Zora, Miner, Jeffrey H, Shaw, Andrey S

“…Given the frequency with which MAP kinase signaling is dysregulated in cancer, much effort has been focused on inhibiting RAS signaling for therapeutic…”
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Harnessing the Unique Structural Properties of Isolated α-Helices by Swanson, Carter J., Sivaramakrishnan, Sivaraj

“…The α-helix is a ubiquitous secondary structural element that is almost exclusively observed in proteins when stabilized by tertiary or quaternary…”
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Viral Attachment Blocking Chimera Composed of DNA Origami and Nanobody Inhibits Pseudorabies Virus Infection In Vitro by Pradhan, Swechchha, Swanson, Carter J., Leff, Chloe, Tengganu, Isadonna, Bergeman, Melissa H., Wisna, Gde B. M., Hogue, Ian B., Hariadi, Rizal F

“…Antivirals are indispensable tools that can be targeted at viral domains directly or at cellular domains indirectly to obstruct viral infections and reduce…”
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The Role of Regulatory Domains in Maintaining Autoinhibition in the Multidomain Kinase PKCα by Sommese, Ruth F., Ritt, Michael, Swanson, Carter J., Sivaramakrishnan, Sivaraj

“…Resolving the conformational dynamics of large multidomain proteins has proven to be a significant challenge. Here we use a variety of techniques to dissect…”
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Conserved Modular Domains Team up to Latch-open Active Protein Kinase Cα by Swanson, Carter J., Ritt, Michael, Wang, William, Lang, Michael J., Narayan, Arvind, Tesmer, John J., Westfall, Margaret, Sivaramakrishnan, Sivaraj

“…Signaling proteins comprised of modular domains have evolved along with multicellularity as a method to facilitate increasing intracellular bandwidth. The…”
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Combining different design strategies for rational affinity maturation of the MICA‐NKG2D interface by Henager, Samuel H., Hale, Melissa A., Maurice, Nicholas J., Dunnington, Erin C., Swanson, Carter J., Peterson, Megan J., Ban, Joseph J., Culpepper, David J., Davies, Luke D., Sanders, Lisa K., McFarland, Benjamin J.

“…We redesigned residues on the surface of MICA, a protein that binds the homodimeric immunoreceptor NKG2D, to increase binding affinity with a series of…”
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Calcium Stimulates Self-Assembly of Protein Kinase C [alpha] In Vitro by Swanson, Carter J, Sommese, Ruth F, Petersen, Karl J, Ritt, Michael, Karslake, Joshua, Thomas, David D, Sivaramakrishnan, Sivaraj

“…Protein kinase C [alpha] (PKC[alpha]) is a nodal regulator in several intracellular signaling networks. PKC[alpha] is composed of modular domains that interact…”
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Non-Canonical Modular Domain Interactions Dictate PKCα Function by Swanson, Carter J., Ritt, Michael, Wang, William, Lang, Michael, Tesmer, John J., Westfall, Margaret, Sivaramakrishnan, Sivaraj

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