Search Results - "Swanier, Jordan"
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Lysine Deacetylase Substrate Selectivity: A Dynamic Ionic Interaction Specific to KDAC8
Published in Biochemistry (Easton) (24-08-2021)“…Lysine acetylation and deacetylation are critical for regulation of many cellular proteins. Despite the importance of this cycle, it is unclear how lysine…”
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Specificity Determinants of Lysine Deacetylases
Published in The FASEB journal (01-05-2022)“…Lysine acetylation is a reversible post‐translational modification that has been found on thousands of nuclear and cytoplasmic proteins. A family of enzymes,…”
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CaBagE: A Cas9-based Background Elimination strategy for targeted, long-read DNA sequencing
Published in PloS one (08-04-2021)“…A substantial fraction of the human genome is difficult to interrogate with short-read DNA sequencing technologies due to paralogy, complex haplotype…”
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Determinants of Lysine Deacetylase 8 Substrate Specificity
Published in The FASEB journal (01-04-2020)“…Abstract only…”
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Specific Ionic Interactions Contribute to Substrate Binding of Lysine Deacetylases
Published in The FASEB journal (01-04-2019)“…Analysis of the human proteome has identified thousands of unique protein sequences that contain acetylated lysine residues in vivo. Lysine deacetylases…”
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Journal Article