Search Results - "Swaminathan, Jagannath"
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A theoretical justification for single molecule peptide sequencing
Published in PLoS computational biology (01-02-2015)“…The proteomes of cells, tissues, and organisms reflect active cellular processes and change continuously in response to intracellular and extracellular cues…”
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Influence of competing metabolic processes on the molecular weight of hyaluronic acid synthesized by Streptococcus zooepidemicus
Published in Biochemical engineering journal (15-01-2010)“…Hyaluronic acid (HA) is a linear high molecular weight glycosaminoglycan polymer with its molecular weight determining its physiological role, rheological…”
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3
Transiently transfected purine biosynthetic enzymes form stress bodies
Published in PloS one (06-02-2013)“…It has been hypothesized that components of enzymatic pathways might organize into intracellular assemblies to improve their catalytic efficiency or lead to…”
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4
Tertiary Amine Coupling by Oxidation for Selective Labeling of Dimethyl Lysine Post-Translational Modifications
Published in Journal of the American Chemical Society (17-04-2024)“…Lysine dimethylation (Kme2) is a crucial post-translational modification (PTM) that regulates biological processes and is implicated in diseases. There is…”
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5
Highly parallel single-molecule identification of proteins in zeptomole-scale mixtures
Published in Nature biotechnology (22-10-2018)“…Single-protein molecules are identified in parallel through fluorescence monitoring of Edman degradation. The identification and quantification of proteins…”
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6
Studies of Surface Preparation for the Fluorosequencing of Peptides
Published in Langmuir (28-12-2021)“…Silica passivating agents have shown great success in minimizing nonspecific protein binding to glass surfaces for imaging and microscopy applications…”
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Photoredox-Catalyzed Decarboxylative C‑Terminal Differentiation for Bulk- and Single-Molecule Proteomics
Published in ACS chemical biology (19-11-2021)“…Methods for the selective labeling of biogenic functional groups on peptides are being developed and used in the workflow of both current and emerging…”
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Peptide Fragment Ion Analyser (PFIA): a simple and versatile tool for the interpretation of tandem mass spectrometric data and de novo sequencing of peptides
Published in Rapid communications in mass spectrometry (30-09-2007)“…The software Peptide Fragment Ion Analyser (PFIA) aids in the analysis and interpretation of tandem mass spectrometric data of peptides. The software package…”
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Evaluating the Effect of Dye–Dye Interactions of Xanthene-Based Fluorophores in the Fluorosequencing of Peptides
Published in Bioconjugate chemistry (15-06-2022)“…A peptide sequencing scheme utilizing fluorescence microscopy and Edman degradation to determine the amino acid position in fluorophore-labeled peptides was…”
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10
Solid-Phase Peptide Capture and Release for Bulk and Single-Molecule Proteomics
Published in ACS chemical biology (19-06-2020)“…The field of proteomics has expanded recently with more sensitive techniques for the bulk measurement of peptides as well as single-molecule techniques. One…”
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A Theoretical Justification for Single Molecule Peptide Sequencing: e1004080
Published in PLoS computational biology (01-02-2015)“…The proteomes of cells, tissues, and organisms reflect active cellular processes and change continuously in response to intracellular and extracellular cues…”
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12
Streamlining Bottom-Up Protein Identification Based on Selective Ultraviolet Photodissociation (UVPD) of Chromophore-Tagged Histidine- and Tyrosine-Containing Peptides
Published in Analytical chemistry (Washington) (01-07-2014)“…We report a fast and highly efficient diazonium reaction that couples a nitroazobenzene chromophore to tyrosine and histidine residues, thus endowing peptides…”
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A self-assembling lanthanide molecular nanoparticle for optical imaging
Published in Dalton transactions : an international journal of inorganic chemistry (14-02-2015)“…Chromophores that incorporate f-block elements have considerable potential for use in bioimaging applications because of their advantageous photophysical…”
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14
Lanthanide nano-drums: a new class of molecular nanoparticles for potential biomedical applications
Published in Faraday discussions (01-01-2014)“…We are developing a new class of lanthanide-based self-assembling molecular nanoparticles as potential reporter molecules for imaging, and as multi-functional…”
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