Search Results - "Swainson, Louise A."

Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques by Vujkovic-Cvijin, Ivan, Swainson, Louise A., Chu, Simon N., Ortiz, Alexandra M., Santee, Clark A., Petriello, Annalise, Dunham, Richard M., Fadrosh, Douglas W., Lin, Din L., Faruqi, Ali A., Huang, Yong, Apetrei, Cristian, Pandrea, Ivona, Hecht, Frederick M., Pilcher, Christopher D., Klatt, Nichole R., Brenchley, Jason M., Lynch, Susan V., McCune, Joseph M.

“…Gut microbes can profoundly modulate mucosal barrier-promoting Th17 cells in mammals. A salient feature of HIV/simian immunodeficiency virus (SIV)…”
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IFN-α blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health by Swainson, Louise A, Sharma, Ashish Arunkumar, Ghneim, Khader, Ribeiro, Susan Pereira, Wilkinson, Peter, Dunham, Richard M, Albright, Rebecca G, Wong, Samson, Estes, Jacob D, Piatak, Michael, Deeks, Steven G, Hunt, Peter W, Sekaly, Rafick-Pierre, McCune, Joseph M

“…Type I IFNs (TI-IFNs) drive immune effector functions during acute viral infections and regulate cell cycling and systemic metabolism. That said, chronic…”
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Higher CD27+CD8+ T cells percentages during suppressive antiretroviral therapy predict greater subsequent CD4+ T cell recovery in treated HIV infection by Seu, Lillian, Ortiz, Gabriel M, Epling, Lorrie, Sinclair, Elizabeth, Swainson, Louise A, Bajpai, Urmila D, Huang, Yong, Deeks, Steven G, Hunt, Peter W, Martin, Jeffrey N, McCune, Joseph M

“…HIV-mediated immune dysfunction may influence CD4(+) T cell recovery during suppressive antiretroviral therapy (ART). We analyzed cellular biomarkers of…”
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Kynurenine 3-Monooxygenase Inhibition during Acute Simian Immunodeficiency Virus Infection Lowers PD-1 Expression and Improves Post-Combination Antiretroviral Therapy CD4 + T Cell Counts and Body Weight by Swainson, Louise A, Ahn, Haelee, Pajanirassa, Priya, Khetarpal, Vinod, Deleage, Claire, Estes, Jacob D, Hunt, Peter W, Munoz-Sanjuan, Ignacio, McCune, Joseph M

“…The kynurenine pathway (KP) is a key regulator of many important physiological processes and plays a harmful role in cancer, many neurologic conditions, and…”
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Expression of the Autoimmune Susceptibility Gene FcRL3 on Human Regulatory T Cells Is Associated with Dysfunction and High Levels of Programmed Cell Death-1 by Swainson, Louise A, Mold, Jeff E, Bajpai, Urmila D, McCune, Joseph M

“…CD4(+)FoxP3(+) regulatory T cells (T(reg)) play a critical role in maintaining self-tolerance and inhibiting autoimmune disease. Despite being a major focus of…”
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A functional variant in FCRL3 is associated with higher Fc receptor-like 3 expression on T cell subsets and rheumatoid arthritis disease activity by Bajpai, Urmila D., Swainson, Louise A., Mold, Jeff E., Graf, Jonathan D., Imboden, John B., McCune, Joseph M.

“…Objective CD4+FoxP3+ Treg cells suppress effector T cells and prevent autoimmune disease. Treg cell function is deficient in active rheumatoid arthritis (RA),…”
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Kynurenine 3-monooxygenase inhibition during acute SIV infection lowers PD-1 expression and improves post-cART CD4+ T cell counts and body weight: KMO inhibition improves clinical outcome in SIV infection by Swainson, Louise A., Ahn, Haelee, Pajanirassa, Priya, Khetarpal, Vinod, Deleage, Claire, Estes, Jacob D., Hunt, Peter W., Munoz-Sanjuan, Ignacio, McCune, Joseph M.

“…The kynurenine pathway (KP) is a key regulator of many important physiological processes and plays a harmful role in cancer, many neurological conditions, and…”
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Higher CD27.sup.+CD8.sup.+ T Cells Percentages during Suppressive Antiretroviral Therapy Predict Greater Subsequent CD4.sup.+ T Cell Recovery in Treated HIV Infection by Seu, Lillian, Ortiz, Gabriel M, Epling, Lorrie, Sinclair, Elizabeth, Swainson, Louise A, Bajpai, Urmila D, Huang, Yong, Deeks, Steven G, Hunt, Peter W, Martin, Jeffrey N, McCune, Joseph M

“…HIV-mediated immune dysfunction may influence CD4.sup.+ T cell recovery during suppressive antiretroviral therapy (ART). We analyzed cellular biomarkers of…”
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Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of PD-1 by Swainson, Louise A., Mold, Jeff E., Bajpai, Urmila D., McCune, Joseph M.

“…CD4 + FoxP3 + regulatory T cells (T reg ) play a critical role in maintaining self tolerance and inhibiting autoimmune disease. Despite being a major focus of…”
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Higher CD27+CD8+ T Cells Percentages during Suppressive Antiretroviral Therapy Predict Greater Subsequent CD4+ T Cell Recovery in Treated HIV Infection: e84091 by Seu, Lillian, Ortiz, Gabriel M, Epling, Lorrie, Sinclair, Elizabeth, Swainson, Louise A, Bajpai, Urmila D, Huang, Yong, Deeks, Steven G, Hunt, Peter W, Martin, Jeffrey N

“…HIV-mediated immune dysfunction may influence CD4+ T cell recovery during suppressive antiretroviral therapy (ART). We analyzed cellular biomarkers of…”
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A functional variant in FCRL3 is associated with higher FcRL3 expression on T cell subsets and rheumatoid arthritis disease activity by Bajpai, Urmila D., Swainson, Louise A., Mold, Jeff E., Graf, Jonathan D., Imboden, John B., McCune, Joseph M.

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