Search Results - "Swain, Puspanjali"
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Mapping Molecular Networks within Clitoria ternatea Linn. against LPS-Induced Neuroinflammation in Microglial Cells, with Molecular Docking and In Vivo Toxicity Assessment in Zebrafish
Published in Pharmaceuticals (Basel, Switzerland) (12-04-2022)“…Clitoria ternatea Linn. (CT), or butterfly pea, is an Ayurvedic plant traditionally used as a brain tonic. Recently, it was reported to be of use in treating…”
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In silico studies, X-ray diffraction analysis and biological investigation of fluorinated pyrrolylated-chalcones in zebrafish epilepsy models
Published in Heliyon (01-02-2023)“…Epilepsy is the third most common known brain disease worldwide. Several antiepileptic drugs (AEDs) are available to improve seizure control. However, the…”
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Preliminary insight on diarylpentanoids as potential antimalarials: In silico, in vitro pLDH and in vivo zebrafish toxicity assessment
Published in Heliyon (15-03-2024)“…Malaria remains a major public health problem worldwide, including in Southeast Asia. Chemotherapeutic agents such as chloroquine (CQ) are effective, but…”
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Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1
Published in Journal of medicinal chemistry (10-02-2022)“…The polo-box domain (PBD) of Plk1 is a promising target for cancer therapeutics. We designed and synthesized novel phosphorylated macrocyclic peptidomimetics…”
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Antifungal activity of synthetic xanthenone against fluconazole-resistant Candida auris and its mechanism of action
Published in Microbial pathogenesis (01-09-2024)“…Candida auris, an emerging multidrug-resistant fungal pathogen discovered in Japan in 2009, poses a significant global health threat, with infections reported…”
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Preliminary insight on diarylpentanoids as potential antimalarials: In silico, in vitro p LDH and in vivo zebrafish toxicity assessment
Published in Heliyon (15-03-2024)“…Malaria remains a major public health problem worldwide, including in Southeast Asia. Chemotherapeutic agents such as chloroquine (CQ) are effective, but…”
Get full text
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