Search Results - "Swain, Lija"

Left Ventricular Unloading Increases the Coronary Collateral Flow Index Before Reperfusion and Reduces Infarct Size in a Swine Model of Acute Myocardial Infarction by Briceno, Natalia, Annamalai, Shiva K, Reyelt, Lara, Crowley, Paige, Qiao, Xiaoying, Swain, Lija, Pedicini, Robert, Foroutanjazi, Sina, Jorde, Lena, Yesodharan, Gemini, Perera, Divaka, Kapur, Navin K

“…Background Unloading the left ventricle and delaying reperfusion reduces infarct size in preclinical models of acute myocardial infarction. We hypothesized…”
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Prolyl‐4‐hydroxylase domain 3 (PHD3) is a critical terminator for cell survival of macrophages under stress conditions by Swain, Lija, Wottawa, Marieke, Hillemann, Annette, Beneke, Angelika, Odagiri, Haruki, Terada, Kazutoyo, Endo, Motoyoshi, Oike, Yuichi, Farhat, Katja, Katschinski, Dörthe M.

“…PHD3 influences apoptotic cell survival decisions in macrophages by altered production of Angiopoietin‐like protein 2. On a molecular level, cells sense…”
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Proceedings of the 3rd annual Acute Cardiac Unloading and REcovery (A-CURE) symposium by Chandrasekaran, Uma, Burkhoff, Daniel, Ishikawa, Kiyotake, Swain, Lija, Sunagawa, Kenji, Møller, Jacob, Santos-Gallego, Carlos, Annamalai, Shiva, Udelson, James, Westenfeld, Ralf, Kapur, Navin, Qiao, Xiaoying, Wiora, Julian, Schäfer, Andreas, Bernhardt, Alexander, Kochar, Ajar, Kloner, Robert, Faraz, Haroon

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CIRCULATING PROTEOMIC ANALYSIS IDENTIFIES REDUCED INFLAMMATION AFTER INITIATION OF HEMODYNAMIC SUPPORT WITH EITHER VENO-ARTERIAL EXTRACORPORAL MEMBRANE OXYGENATION OR IMPELLA IN PATIENTS WITH CARDIOGENIC SHOCK by Kapur, Navin, Diakos, Nikolas, Swain, Lija, Bhave, Shreyas, Qiao, Xiaoying

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TCT-458 Use of a Long Femoral Return Cannula Positioned in the Thoracic Aorta With VA-ECMO Resolves Differential Hypoxemia in a Preclinical Model of North South Syndrome by Kapur, Navin, Reyelt, Lara, Stolyarov, Arik, Bhave, Shreyas, Mahmoudi, Elena, Everett, Kay, Qiao, Xiaoying, Swain, Lija

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Abstract Tu136: HIF-1α a novel therapeutic target to reduce Cardiac Ischemia Reperfusion Injury during AMI by Swain, Lija, Reyelt, Lara, Qiao, Xiaoying, Bhave, Shreyas, Everett, Kay, Mahmoudi, Elena, Kapur, Navin

“…Abstract only Acute myocardial infarction (AMI) is a major cause of mortality worldwide. In preclinical models of AMI, using a trans-valvular pump (TVP) to…”
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Abstract P2011: Reduced Activity Of Activin Like Kinase 1 (ALK1) Increases Mortality And Myocardial Rupture After Acute Myocardial Infarction by Bhave, Shreyas, Esposito, Michele, Swain, Lija, Qiao, Xiaoying, Martin, Gregory, Everett, Kay, Kapur, Navin K

“…Abstract only Introduction: Acute myocardial infarction (AMI) is a primary cause of heart failure (HF). Transforming growth factor beta (TGFβ) plays a central…”
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TCT-467 Prolonged Occlusion of the Superior Vena Cava Using the PreCardia System Reduces Cardiac Filling and Renal Venous Pressures Without Causing Cerebral Injury in a Preclinical Model of Systemic Congestion by Kapur, Navin, Reyelt, Lara, Stolyarov, Arik, Bhave, Shreyas, Mahmoudi, Elena, Curran, Jerry, Unudurthi, Sathya, Qiao, Xiaoying, Swain, Lija

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TCT-814 Inflammation as a Predictor of Outcomes in Patients With Cardiogenic Shock Supported by a Percutaneous Mechanical Support Device by Diakos, Nikolaos, Thayer, Katherine, Newman, Sarah, Swain, Lija, Kapur, Navin

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Abstract P2124: Trans-valvular Unloading Protects Against Post-reperfusion Injury Via Hif-1a In Preclinical Models Of Acute Myocardial Infarction by Swain, Lija, Reyelt, Lara A, Qia, Xiaoying, Bhave, Shreyas, Everett, Kay, Mahmoudi, Elena, Majumdar, Monica, Warner, Mary, Kapur, Navin K

“…Abstract only Acute myocardial infarction (AMI) is a major cause of heart failure and mortality worldwide. Reducing left ventricular (LV) workload using a…”
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Abstract 14103: Loss of Bone Morphogenetic Protein (BMP) 9 Activity Reduces Survival and Increases Collagen Turnover via Enhanced Matrix Metalloproteinase Activity After Acute Myocardial Infarction by Bhave, Shreyas, Esposito, Michele, Swain, Lija, QIAO, Xiaoying, Martin, Gregory, Everett, Kay, Kapur, Navin K

“…IntroductionAcute myocardial infarction (AMI) is a major cause of heart failure and mortality. The extracellular matrix plays a central role in post-infarct…”
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182: VA-ECMO increases markers of vascular stress in the abdominal section of the aorta in a pig model of AMI by Bhave, Shreyas, Swain, Lija, Qiao, Xiaoying, Reyelt, Lara, Mahmoudi, Elena, Stolyarov, Arik, Kapur, Navin

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Generation of a Cardiomyocyte-Specific Redox Sensor Mouse Line by Swain, Lija, Kesemeyer, Andrea, Katschinski, Doerthe

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359 - Generation of a Cardiomyocyte-Specific Redox Sensor Mouse Line by Swain, Lija, Kesemeyer, Andrea, Katschinski, Doerthe

“…Redox changes can stimulate signal-transduction pathways, which are important for cell physio- and pathophysiology. Regarding cardiovascular diseases these…”
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Transvalvular Ventricular Unloading Before Reperfusion in Acute Myocardial Infarction by Swain, Lija, Reyelt, Lara, Bhave, Shreyas, Qiao, Xiaoying, Thomas, Corinne J, Zweck, Elric, Crowley, Paige, Boggins, Courtney, Esposito, Michele, Chin, Michael, Karas, Richard H, O'Neill, William, Kapur, Navin K

“…Myocardial damage due to acute ST-segment elevation myocardial infarction (STEMI) remains a significant global health problem. New approaches to limit…”
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BONE MORPHOGENETIC PROTEIN-9 (BMP9) IS REQUIRED FOR SURVIVAL AND LIMITS LEFT VENTRICULAR MATRIX METALLOPROTEINASE ACTIVITY AFTER ACUTE MYOCARDIAL INFARCTION by Bhave, Shreyas, Swain, Lija, Qiao, Xiaoying, Esposito, Michele, Martin, Gregory, Everett, Kay, Surks, William, Aryaputra, Tejasvi, Kapur, Navin

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Abstract GS.08: Cardiolipin Is A Novel Target Of Therapy To Mitigate Myocardial Injury Due To Veno-arterial Extracorporeal Membrane Oxygenation (va-ecmo) by Kapur, Navin K, Swain, Lija, Bhave, Shreyas, Qiao, Xiaoying, Reyelt, Lara A, Mahmoudi, Elena, Everett, Kay, Warner, Mary, Awata, Junya, Chin, Michael T

“…Abstract only Cardiolipin (CL) is a mitochondrial specific phospholipid that maintains integrity of the electron transport chain (ETC) and plays a central role…”
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Abstract 13180: Trans-Valvular Unloading Reduces Anaerobic Glycolysis Before Reperfusion and Preserves Energy Substrate Utilization After Reperfusion in Models of Acute Myocardial Infarction by Swain, Lija, QIAO, Xiaoying, Reyelt, Lara A, Zweck, Elric, Everett, Kay, Majumdar, Monica, Mahmoudi, Elena, Bhave, Shreyas, Diakos, Nikolaos, Kapur, Navin K

“…BackgroundThe impact of mechanical left ventricular (LV) unloading before reperfusion on myocardial energetics in acute myocardial infarction (AMI) is unknown…”
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Abstract 589: Left Ventricular Unloading and Delayed Coronary Reperfusion Protects the Structural and Functional Integrity of Mitochondrial Complex 1 in a Preclinical Model of Acute Myocardial Infarction by Swain, Lija, Qiao, Xiaoying, Reyelt, Lara, Annamalai, Shiva, Crowley, Paige, Boggins, Courtney, Kapur, Navin K

“…Abstract only Background: Mitochondrial Complex 1 (MC1) plays a key role in energy metabolism during myocardial ischemia-reperfusion injury (M-IRI). Disruption…”
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COMBINING VA-ECMO AND IMPELLA (EC-PELLA) BEFORE REPERFUSION MITIGATES LEFT VENTRICULAR INJURY DUE TO VA-ECMO IN ACUTE MYOCARDIAL INFARCTION by Everett, Kay, Swain, Lija, Lara, Reyelt, Majumdar, Monica, Qiao, Xiaoying, Bhave, Shreyas, Warner, Mary, Mahmoudi, Elena, Surks, Will, Aryaputra, Tejasvi, Goel, Siya, Kapur, Navin

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