Search Results - "Swafford, Austin D."
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Age- and Sex-Dependent Patterns of Gut Microbial Diversity in Human Adults
Published in mSystems (01-07-2019)“…Gut microbial diversity changes throughout the human life span and is known to be associated with host sex. We investigated the association of age, sex, and…”
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Thermal ablation of tumor cells with antibody-functionalized single-walled carbon nanotubes
Published in Proceedings of the National Academy of Sciences - PNAS (24-06-2008)“…Single-walled carbon nanotubes (CNTs) emit heat when they absorb energy from near-infrared (NIR) light. Tissue is relatively transparent to NIR, which suggests…”
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A comparison of six DNA extraction protocols for 16S, ITS and shotgun metagenomic sequencing of microbial communities
Published in BioTechniques (01-06-2022)“…Microbial communities contain a broad phylogenetic diversity of organisms; however, the majority of methods center on describing bacteria and archaea. Fungi…”
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Human Skin, Oral, and Gut Microbiomes Predict Chronological Age
Published in mSystems (11-02-2020)“…Human gut microbiomes are known to change with age, yet the relative value of human microbiomes across the body as predictors of age, and prediction robustness…”
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A comparison of DNA/RNA extraction protocols for high-throughput sequencing of microbial communities
Published in BioTechniques (01-03-2021)“…One goal of microbial ecology researchers is to capture the maximum amount of information from all organisms in a sample. The recent COVID-19 pandemic, caused…”
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Salivary bacterial signatures in depression-obesity comorbidity are associated with neurotransmitters and neuroactive dipeptides
Published in BMC microbiology (14-03-2022)“…Depression and obesity are highly prevalent, often co-occurring conditions marked by inflammation. Microbiome perturbations are implicated in…”
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Challenges in the construction of knowledge bases for human microbiome-disease associations
Published in Microbiome (05-09-2019)“…The last few years have seen tremendous growth in human microbiome research, with a particular focus on the links to both mental and physical health and…”
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Phylogeny-Aware Analysis of Metagenome Community Ecology Based on Matched Reference Genomes while Bypassing Taxonomy
Published in mSystems (26-04-2022)“…We introduce the operational genomic unit (OGU) method, a metagenome analysis strategy that directly exploits sequence alignment hits to individual reference…”
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An Allele of IKZF1 (Ikaros) Conferring Susceptibility to Childhood Acute Lymphoblastic Leukemia Protects Against Type 1 Diabetes
Published in Diabetes (New York, N.Y.) (01-03-2011)“…IKZF1 encoding Ikaros, an essential regulator of lymphopoiesis and immune homeostasis, has been implicated in the development of childhood acute lymphoblastic…”
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High-Resolution Longitudinal Dynamics of the Cystic Fibrosis Sputum Microbiome and Metabolome through Antibiotic Therapy
Published in mSystems (23-06-2020)“…Microbial diversity in the cystic fibrosis (CF) lung decreases over decades as pathogenic bacteria such as Pseudomonas aeruginosa take over. The dynamics of…”
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EMPress Enables Tree-Guided, Interactive, and Exploratory Analyses of Multi-omic Data Sets
Published in mSystems (16-03-2021)“…Standard workflows for analyzing microbiomes often include the creation and curation of phylogenetic trees. Here we present EMPress, an interactive web tool…”
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Feasibility of using alternative swabs and storage solutions for paired SARS-CoV-2 detection and microbiome analysis in the hospital environment
Published in Microbiome (22-01-2021)“…Determining the role of fomites in the transmission of SARS-CoV-2 is essential in the hospital setting and will likely be important outside of medical…”
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Microbiome analyses of blood and tissues suggest cancer diagnostic approach
Published in Nature (London) (01-03-2020)“…Systematic characterization of the cancer microbiome provides the opportunity to develop techniques that exploit non-human, microorganism-derived molecules in…”
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Signatures of HIV and Major Depressive Disorder in the Plasma Microbiome
Published in Microorganisms (Basel) (01-04-2023)“…Inter-individual differences in the gut microbiome are linked to alterations in inflammation and blood-brain barrier permeability, which may increase the risk…”
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Swapping Metagenomics Preprocessing Pipeline Components Offers Speed and Sensitivity Increases
Published in mSystems (26-04-2022)“…Increasing data volumes on high-throughput sequencing instruments such as the NovaSeq 6000 leads to long computational bottlenecks for common metagenomics data…”
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Pan-cancer analyses reveal cancer-type-specific fungal ecologies and bacteriome interactions
Published in Cell (29-09-2022)“…Cancer-microbe associations have been explored for centuries, but cancer-associated fungi have rarely been examined. Here, we comprehensively characterize the…”
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Best practices for analysing microbiomes
Published in Nature reviews. Microbiology (01-07-2018)“…Complex microbial communities shape the dynamics of various environments, ranging from the mammalian gastrointestinal tract to the soil. Advances in DNA…”
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Metabolome-Informed Microbiome Analysis Refines Metadata Classifications and Reveals Unexpected Medication Transfer in Captive Cheetahs
Published in mSystems (10-03-2020)“…Even high-quality collection and reporting of study metadata in microbiome studies can lead to various forms of inadvertently missing or mischaracterized…”
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Qiita: rapid, web-enabled microbiome meta-analysis
Published in Nature methods (01-10-2018)“…Multi-omic insights into microbiome function and composition typically advance one study at a time. However, in order for relationships across studies to be…”
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Mass spectrometry searches using MASST
Published in Nature biotechnology (2020)Get full text
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