Search Results - "Svrčková, Katarína"

Hydrazones of 4-(Trifluoromethyl)benzohydrazide as New Inhibitors of Acetyl- and Butyrylcholinesterase by Krátký, Martin, Svrčková, Katarína, Vu, Quynh Anh, Štěpánková, Šárka, Vinšová, Jarmila

“…Based on the broad spectrum of biological activity of hydrazide-hydrazones, trifluoromethyl compounds, and clinical usage of cholinesterase inhibitors, we…”
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Novel Iodinated Hydrazide-hydrazones and their Analogues as Acetyl- and Butyrylcholinesterase Inhibitors by Krátký, Martin, Štěpánková, Šárka, Brablíková, Michaela, Svrčková, Katarína, Švarcová, Markéta, Vinšová, Jarmila

“…Hydrazide-hydrazones have been known as scaffold with various biological activities including inhibition of acetyl- (AChE) and butyrylcholinesterase (BuChE)…”
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N -Alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides and Their Analogues: Synthesis and Multitarget Biological Activity by Krátký, Martin, Baranyai, Zsuzsa, Štěpánková, Šárka, Svrčková, Katarína, Švarcová, Markéta, Stolaříková, Jiřina, Horváth, Lilla, Bősze, Szilvia, Vinšová, Jarmila

“…Based on the isosterism concept, we have designed and synthesized homologous -alkyl-2-[4-(trifluoromethyl)benzoyl]hydrazine-1-carboxamides (from C to C ) as…”
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N-[3,5-Bis(trifluoromethyl)phenyl]-5-bromo-2-hydroxybenzamide Analogues: Novel Acetyl- and Butyrylcholinesterase Inhibitors by Krátký, Martin, Jaklová, Karolína, Štěpánková, Šárka, Svrčková, Katarína, Pflégr, Václav, Vinšová, Jarmila

“…Development of acetyl- (AChE) and butyrylcholinesterase (BuChE) inhibitors belongs to viable strategies for the treatment of dementia and other diseases…”
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5-Aryl-1,3,4-oxadiazol-2-amines Decorated with Long Alkyl and Their Analogues: Synthesis, Acetyl- and Butyrylcholinesterase Inhibition and Docking Study by Pflégr, Václav, Štěpánková, Šárka, Svrčková, Katarína, Švarcová, Markéta, Vinšová, Jarmila, Krátký, Martin

“…2,5-Disubstituted 1,3,4-oxadiazoles are privileged versatile scaffolds in medicinal chemistry that have exhibited diverse biological activities. Acetyl- (AChE)…”
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Novel Aminoguanidine Hydrazone Analogues: From Potential Antimicrobial Agents to Potent Cholinesterase Inhibitors by Krátký, Martin, Štěpánková, Šárka, Konečná, Klára, Svrčková, Katarína, Maixnerová, Jana, Švarcová, Markéta, Janďourek, Ondřej, Trejtnar, František, Vinšová, Jarmila

“…A series of thirty-one hydrazones of aminoguanidine, nitroaminoguanidine, 1,3-diaminoguanidine, and (thio)semicarbazide were prepared from various aldehydes,…”
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Novel Inhibitors of Acetyl- and Butyrylcholinesterase Derived from Benzohydrazides: Synthesis, Evaluation and Docking Study by Houngbedji, Neto-Honorius, Štěpánková, Šárka, Pflégr, Václav, Svrčková, Katarína, Švarcová, Markéta, Vinšová, Jarmila, Krátký, Martin

“…On the basis of previous reports, novel 2-benzoylhydrazine-1-carboxamides were designed as potential inhibitors of acetylcholinesterase (AChE) and…”
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Novel Sulfonamide-Based Carbamates as Selective Inhibitors of BChE by Magar, Pratibha, Parravicini, Oscar, Štěpánková, Šárka, Svrčková, Katarina, Garro, Adriana D., Jendrzejewska, Izabela, Pauk, Karel, Hošek, Jan, Jampílek, Josef, Enriz, Ricardo D., Imramovský, Aleš

“…A series of 14 target benzyl [2-(arylsulfamoyl)-1-substituted-ethyl]carbamates was prepared by multi-step synthesis and characterized. All the final compounds…”
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New 3-amino-2-thioxothiazolidin-4-one-based inhibitors of acetyl- and butyryl-cholinesterase: synthesis and activity by Krátký, Martin, Nováčková, Karolína, Svrčková, Katarína, Švarcová, Markéta, Štěpánková, Šárka

“…2-Thioxothiazolidin-4-one represents a versatile scaffold in drug development. The authors used it to prepare new potent acetylcholinesterase (AChE) and…”
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The synthesis and cholinesterase inhibitory activities of solasodine analogues with seven-membered F ring by Kiełczewska, Urszula, Jorda, Radek, Gonzalez, Gabriel, Morzycki, Jacek W., Ajani, Haresh, Svrčková, Katarína, Štěpánková, Šárka, Wojtkielewicz, Agnieszka

“…[Display omitted] •A series of solasodine analogues with 5/7 spiroether unit were synthesized.•Solasodine, 22a(N)-homo-, and 26a-homosolasodine analogues were…”
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Ring-fused 3β-acetoxyandrost-5-enes as novel neuroprotective agents with cholinesterase inhibitory properties by Gonzalez, Gabriel, Kvasnica, Miroslav, Svrčková, Katarína, Štěpánková, Šárka, Santos, Joana R.C., Peřina, Miroslav, Jorda, Radek, Lopes, Susana M.M., Melo, Teresa M.V.D. Pinho e

“…Alzheimer´s disease (AD) is an intellectual disorder caused by organic brain damage and cerebral atrophy, characterized by the loss of memory, judgment, and…”
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Novel propargylamine-based inhibitors of cholinesterases and monoamine oxidases: Synthesis, biological evaluation and docking study by Krátký, Martin, Vu, Quynh Anh, Štěpánková, Šárka, Maruca, Annalisa, Silva, Tiago Barros, Ambrož, Martin, Pflégr, Václav, Rocca, Roberta, Svrčková, Katarína, Alcaro, Stefano, Borges, Fernanda, Vinšová, Jarmila

“…[Display omitted] •New compounds combine propargylamine and salicylic/cinnamic scaffolds.•The compounds exhibited dual inhibition of AChE, BuChE and…”
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Trimethoxycinnamates and Their Cholinesterase Inhibitory Activity by Kos, Jiri, Strharsky, Tomas, Stepankova, Sarka, Svrckova, Katarina, Oravec, Michal, Hosek, Jan, Imramovsky, Ales, Jampilek, Josef

“…A series of twelve nature-inspired 3,4,5-trimethoxycinnamates were prepared and characterized. All compounds, including the starting 3,4,5-trimethoxycinnamic…”
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