Search Results - "Sviben, Sanja"
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Hierarchically-structured metalloprotein composite coatings biofabricated from co-existing condensed liquid phases
Published in Nature communications (13-02-2020)“…Complex hierarchical structure governs emergent properties in biopolymeric materials; yet, the material processing involved remains poorly understood. Here, we…”
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Functional characterization of the dural sinuses as a neuroimmune interface
Published in Cell (18-02-2021)“…Despite the established dogma of central nervous system (CNS) immune privilege, neuroimmune interactions play an active role in diverse neurological disorders…”
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A vacuole-like compartment concentrates a disordered calcium phase in a key coccolithophorid alga
Published in Nature communications (14-04-2016)“…Coccoliths are calcitic particles produced inside the cells of unicellular marine algae known as coccolithophores. They are abundant components of sea-floor…”
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Author Correction: Hierarchically-structured metalloprotein composite coatings biofabricated from co-existing condensed liquid phases
Published in Nature communications (31-03-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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5
A joint proteomic and genomic investigation provides insights into the mechanism of calcification in coccolithophores
Published in Nature communications (23-06-2023)“…Coccolithophores are globally abundant, calcifying microalgae that have profound effects on marine biogeochemical cycles, the climate, and life in the oceans…”
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Epidermal Cell Surface Structure and Chitin-Protein Co-assembly Determine Fiber Architecture in the Locust Cuticle
Published in ACS applied materials & interfaces (10-06-2020)“…The geometrical similarity of helicoidal fiber arrangement in many biological fibrous extracellular matrices, such as bone, plant cell wall, or arthropod…”
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SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
Published in JACC. Basic to translational science (01-04-2021)“…[Display omitted] •SARS-CoV-2 directly infects cardiomyocytes in patients with COVID-19 myocarditis and does not infect cardiac macrophages, fibroblasts, or…”
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Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination
Published in Cell reports (Cambridge) (25-04-2023)“…Demyelination is a hallmark of multiple sclerosis, leukoencephalopathies, cerebral vasculopathies, and several neurodegenerative diseases. The cuprizone mouse…”
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Gold nanoparticle-enhanced X-ray microtomography of the rodent reveals region-specific cerebrospinal fluid circulation in the brain
Published in Nature communications (27-01-2023)“…Cerebrospinal fluid (CSF) is essential for the development and function of the central nervous system (CNS). However, the brain and its interstitium have…”
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Epithelial Abnormalities in the Small Intestine of Zambian Children With Stunting
Published in Frontiers in medicine (16-03-2022)“…Environmental enteropathy (EE) contributes to impaired linear growth (stunting), in millions of children worldwide. We have previously reported that confocal…”
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Trace‐Element Incorporation into Intracellular Pools Uncovers Calcium‐Pathways in a Coccolithophore
Published in Advanced science (01-10-2017)“…Many organisms form minerals from precursor phases that crystallize under strict biological control. The dynamic intracellular processes of formation,…”
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Microfluidic-like fabrication of metal ion-cured bioadhesives by mussels
Published in Science (American Association for the Advancement of Science) (08-10-2021)“…To anchor in seashore habitats, mussels fabricate adhesive byssus fibers that are mechanically reinforced by protein-metal coordination mediated by…”
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Three-dimensional structural interrelations between cells, extracellular matrix, and mineral in normally mineralizing avian leg tendon
Published in Proceedings of the National Academy of Sciences - PNAS (23-06-2020)“…The spatial-temporal relationship between cells, extracellular matrices, and mineral deposits is fundamental for an improved understanding of mineralization…”
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Immuno-scanning electron microscopy of islet primary cilia
Published in Journal of cell science (15-10-2024)“…The definitive demonstration of protein localization on primary cilia has been a challenge for cilia biologists. Primary cilia are solitary thread-like…”
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Scanning electron microscopy of human islet cilia
Published in Proceedings of the National Academy of Sciences - PNAS (30-05-2023)“…Human islet primary cilia are vital glucose-regulating organelles whose structure remains uncharacterized. Scanning electron microscopy (SEM) is a useful…”
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16
Sleep deprivation exacerbates microglial reactivity and Aβ deposition in a TREM2 -dependent manner in mice
Published in Science translational medicine (26-04-2023)“…Sleep loss is associated with cognitive decline in the aging population and is a risk factor for Alzheimer's disease (AD). Considering the crucial role of…”
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Miswiring of Merkel cell and pruriceptive C fiber drives the itch-scratch cycle
Published in Science translational medicine (13-07-2022)“…Itch sensation provokes the scratch reflex to protect us from harmful stimuli in the skin. Although scratching transiently relieves acute itch through…”
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Modeling late-onset Alzheimer's disease neuropathology via direct neuronal reprogramming
Published in Science (American Association for the Advancement of Science) (02-08-2024)“…Late-onset Alzheimer's disease (LOAD) is the most common form of Alzheimer's disease (AD). However, modeling sporadic LOAD that endogenously captures hallmark…”
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Modeling neuropathology of Alzheimer’s disease in aged patient‐derived neurons through 3D direct neuronal reprogramming
Published in Alzheimer's & dementia (01-12-2023)“…Background Alzheimer’s disease (AD) is the most common form of adult‐onset neurodegenerative diseases characterized by three hallmarks of neuropathology…”
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Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin DeficiencySummary
Published in Cellular and molecular gastroenterology and hepatology (01-01-2024)“…Background & Aims: In the classic form of α1-antitrypsin deficiency (ATD), the misfolded α1-antitrypsin Z (ATZ) variant accumulates in the endoplasmic…”
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