Search Results - "Svetlana S Kirikovich"
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The Molecular Aspects of Functional Activity of Macrophage-Activating Factor GcMAF
Published in International journal of molecular sciences (12-12-2023)“…Group-specific component macrophage-activating factor (GcMAF) is the vitamin D -binding protein (DBP) deglycosylated at Thr . The protein is believed to…”
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The Macrophage Activator GcMAF-RF Enhances the Antitumor Effect of Karanahan Technology through Induction of M2–M1 Macrophage Reprogramming
Published in Journal of immunology research (29-02-2024)“…Macrophages are the immune cells of high-immunological plasticity, which can exert both pro- and anti-inflammatory activity, as well as repolarize their…”
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The New General Biological Property of Stem-like Tumor Cells (Part II: Surface Molecules, Which Belongs to Distinctive Groups with Particular Functions, Form a Unique Pattern Characteristic of a Certain Type of Tumor Stem-like Cells)
Published in International journal of molecular sciences (13-12-2022)“…An ability of poorly differentiated cells of different genesis, including tumor stem-like cells (TSCs), to internalize extracellular double-stranded DNA…”
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Analysis of the Biological Properties of Blood Plasma Protein with GcMAF Functional Activity
Published in International journal of molecular sciences (22-07-2022)“…The main problem related to the studies focusing on group-specific component protein-derived macrophage-activating factor (GcMAF) is the lack of clarity about…”
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Impact of Double-Stranded RNA Internalization on Hematopoietic Progenitors and Krebs-2 Cells and Mechanism
Published in International journal of molecular sciences (01-03-2023)“…It is well-established that double-stranded RNA (dsRNA) exhibits noticeable radioprotective and radiotherapeutic effects. The experiments conducted in this…”
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Production of GcMAF with Anti-Inflammatory Properties and Its Effect on Models of Induced Arthritis in Mice and Cystitis in Rats
Published in Current issues in molecular biology (28-09-2024)“…Vitamin D transporter (DBP) is a multifunctional protein. Site-specific deglycosylation results in its conversion to group-specific component protein-derived…”
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The new general biological property of stem-like tumor cells Part I. Peculiarities of the process of the double-stranded DNA fragments internalization into stem-like tumor cells
Published in Frontiers in genetics (08-09-2022)“…Stem-like tumor cells of ascites carcinoma Krebs-2 and Epstein-Barr virus-induced B-lymphoma were shown to possess the innate capability of binding and…”
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Experimental Comparison of the In Vivo Efficacy of Two Novel Anticancer Therapies
Published in Anticancer research (01-07-2021)“…Background/Aim: We compared the therapeutic efficacy of two recently developed experimental anticancer technologies: 1) in situ vaccination based on local…”
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Characterization of biological peculiarities of the radioprotective activity of double-stranded RNA isolated from Saccharomyces сerevisiae
Published in International journal of radiation biology (01-09-2020)“…Protection from ionizing radiation is the most important component in the curing malignant neoplasms, servicing atomic reactors, and resolving the situations…”
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Approbation of the Cancer Treatment Approach Based on the Eradication of TAMRA+ Cancer Stem Cells in a Model of Murine Cyclophosphamide Resistant Lymphosarcoma
Published in Anticancer research (01-02-2020)“…We previously have described the "3+1" tumors cure approach consisting of individual time schedule of cyclophosphamide and dsDNA preparation administrations…”
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Karanahan: A Potential New Treatment Option for Human Breast Cancer and Its Validation in a Clinical Setting
Published in Breast cancer : basic and clinical research (2022)“…Introduction: Karanahan, a cancer treatment technology aimed at eradicating tumor-initiating stem cells, has already proven effective in 7 tumor models…”
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Efficacy of the new therapeutic approach in curing malignant neoplasms on the model of human glioblastoma
Published in Cancer biology & medicine (01-08-2021)“…Glioma is a highly invasive tumor, frequently disposed in essential areas of the brain, which makes its surgical excision extremely difficult; meanwhile…”
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Ultrastructural analysis of the Krebs-2 ascites cancer cells treated with extracellular double-stranded DNA preparation
Published in Ultrastructural pathology (02-01-2019)“…Electron-microscopic analysis of the ultrastructure of the Krebs-2 carcinoma ascites cells in the first 90 min immediately after their exposure to fragmented…”
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The Basis of Anticancer Immunity Mechanism Induced by In Situ Vaccination
Published in Žurnal Sibirskogo federalʹnogo universiteta. Seriâ Biologiâ (Online) (01-09-2020)“…The present review is an attempt to characterize the principles of both onset and development of the systemic antitumor immune response triggered by in situ…”
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The Basis of Anticancer Immunity Mechanism Induced by In Situ Vaccination
Published in Žurnal Sibirskogo federalʹnogo universiteta. Seriâ Biologiâ (Online) (01-07-2020)“…В обзоре предпринята попытка охарактеризовать принципы возникновения и распространения системного противоопухолевого иммунного ответа при in situ вакцинации -…”
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A Potential New Treatment Option for Human Breast Cancer and Its Validation in a Clinical Setting
Published in Breast cancer : basic and clinical research (01-02-2022)“…Introduction: Karanahan , a cancer treatment technology aimed at eradicating tumor-initiating stem cells, has already proven effective in 7 tumor models…”
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Epigenetic variability of unlinked enzyme genes in agamospermous progeny of sugar beet
Published in Sugar tech : an international journal of sugar crops & related industries (01-03-2003)Get full text
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