Search Results - "Sverdlov, A L"

Cardiotoxicity of Radiation Therapy: Mechanisms, Management, and Mitigation by Ell, P., Martin, J. M., Cehic, D. A., Ngo, D. T. M, Sverdlov, A. L.

“…Opinion Statement Radiation therapy is a key component of modern-day cancer therapy and can reduce the rates of recurrence and death from cancer. However, it…”
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Women's cardiovascular health - the cardio-oncologic jigsaw by Ray, M, Butel-Simoes, L E, Lombard, J M, Nordman, I I C, Van der Westhuizen, A, Collins, N J, Ngo, D T M, Sverdlov, A L

“…Improvements in cancer care have led to an exponential increase in cancer survival. This is particularly the case for breast cancer, where 5-year survival in…”
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New onset atrial fibrillation is associated with elevated Galectin-3 levels by Chen, D, Procter, N, Goh, V, Liu, S, Chua, S.J, Assadi-Khansari, B, Stewart, S, Horowitz, J.D, Sverdlov, A.L, Ngo, D.T

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European Society of Cardiology quality indicators for the prevention and management of cancer therapy-related cardiovascular toxicity in cancer treatment by Lee, G A, Aktaa, S, Baker, E, Gale, C P, Yaseen, Israa F, Gulati, G, Asteggiano, R, Szmit, S, Cohen-Solal, A, Abdin, A, Jurczak, W, Garrido Lopez, P, Sverdlov, A L, Tocchetti, C G, Barac, A, Parrini, I, Zamorano, P, Iakobishvili, Z, Pudil, R, Badimon, L, Kirby, A M, Blaes, A H, Farmakis, D, Curigliano, G, Stephens, R, Lyon, A R, Lopez-Fernandez, T

“…Abstract Aims To develop quality indicators (QIs) for the evaluation of the prevention and management of cancer therapy-related cardiovascular toxicity…”
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Prevention of aortic valve stenosis: a realistic therapeutic target? by Ngo, D T, Sverdlov, A L, Horowitz, J D

“…Aortic valve stenosis (AS) is the most common form of valvular heart disease in the Western world, affecting ~40% of the population over the age of 80; to date…”
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Anthracycline-Induced Cardiotoxicity: Time to Focus on Cardioprotection Again by Croft, A.J., Ngo, D.T.M., Sverdlov, A.L.

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Elevated parathyroid hormone predicts high asymmetric dimethylarginine (ADMA) concentrations in obese diabetic patients by Amarasekera, A.T, Sverdlov, A.L, Horowitz, J.D, Ngo, D.T

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Determinants of insulin responsiveness in young women: Impact of polycystic ovarian syndrome, nitric oxide, and vitamin D by Ngo, D.T.M., Chan, W.P., Rajendran, S., Heresztyn, T., Amarasekera, A., Sverdlov, A.L., O’Loughlin, P.D., Morris, H.A., Chirkov, Y.Y., Norman, R.J., Horowitz, J.D.

“…► Polycystic ovarian syndrome (PCOS) is associated with endothelial dysfunction and platelet NO resistance. ► However, PCOS is also associated with insulin…”
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Redefining the natural history of calcific aortic stenosis: lessons from Laennec by Sverdlov, A. L., Ngo, D. T., Horowitz, J. D.

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The nitric oxide redox sibling nitroxyl partially circumvents impairment of platelet nitric oxide responsiveness by Dautov, R.F., Ngo, D.T.M., Licari, G., Liu, S., Sverdlov, A.L., Ritchie, R.H., Kemp-Harper, B.K., Horowitz, J.D., Chirkov, Y.Y.

“…•NO resistance is a predictor of cardiac event risk.•In NO-resistant subjects, responses to an HNO donor are largely preserved.•NO resistance circumvention may…”
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The endogenous NOS inhibitor asymmetric dimethylarginine (ADMA) predicts LV mass independent of afterload by Sverdlov, A.L., Ngo, D.T.M., Nightingale, A.K., Rajendran, S., Mishra, K., Heresztyn, T., Ritchie, R.H., Marwick, T.H., Frenneaux, M.P., Horowitz, J.D.

“…Nitric oxide (NO) is a modulator of left ventricular hypertrophy (LVH) and myocardial relaxation. The impact of NO availability on development of LVH has never…”
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Mechanism(s) for age-related sex differences in diet-induced cardiomyopathy: role of RNA methylation by Croft, A, Kelly, C, Chen, D, Murtha, L, Sugito, S, Boyle, A, Sverdlov, A L, Ngo, D T M

“…Abstract Background/Introduction Age and sexual dimorphism contribute to the differential cardiometabolic dysfunctions associated with diet-induced obesity…”
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Adipose-targeted overexpression of mitochondrial-targeted catalase does not improve cardio-metabolic parameters in mice with diet-induced obesity by Croft, A J, Kelly, C, Chen, D, Murtha, L, Sugito, S, Boyle, A, Sverdlov, A L, Ngo, D T M

“…Abstract Background Obesity is associated with significant cardio-metabolic complications. Adipokines, and cytokines released from adipose tissue (AT)…”
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Heart failure is associated with low circulating levels of secreted frizzled receptor protein 5 (Sfrp5) by Kelly, C, Chu, M, Untaru, R, Assadi-Khansari, B, Chen, D, Croft, A, Horowitz, J, Sverdlov, A L, Ngo, D T M

“…Abstract Background/Introduction Obesity and metabolic dysregulation are closely associated with the pathophysiology of multiple cardiovascular diseases (CVD)…”
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Elevated parathyroid hormone predicts high asymmetric dimethylarginine (ADMA) concentrations; independent of vitamin D status by Amarasekera, A. T., Sverdlov, A. L., Roberts, M. S., Horowitz, J. D., Ngo, D. T.

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Thioredoxin-Interacting Protein: Pathophysiology and Emerging Pharmacotherapeutics in Cardiovascular Disease and Diabetes by Chong, Cher-Rin, Chan, Wai Ping A., Nguyen, Thanh H., Liu, Saifei, Procter, Nathan E. K., Ngo, Doan T., Sverdlov, Aaron L., Chirkov, Yuliy Y., Horowitz, John D.

“…The thioredoxin system, which consists of thioredoxin (Trx), nicotinamide adenine dinucleotide phosphate (NADPH) and thioredoxin reductase (TrxR), has emerged…”
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