Search Results - "Svenson, Sonke"

Dendrimers in biomedical applications—reflections on the field by Svenson, Sönke, Tomalia, Donald A.

“…The formation of particulate systems with well-defined sizes and shapes is of eminent interest in certain medical applications such as drug delivery, gene…”
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Dendrimers in biomedical applications—reflections on the field by Svenson, Sönke, Tomalia, Donald A.

“…The formation of particulate systems with well-defined sizes and shapes is of eminent interest in certain medical applications such as drug delivery, gene…”
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The dendrimer paradox--high medical expectations but poor clinical translation by Svenson, Sonke

“…This review was written with the intention to critically evaluate the status of dendrimers as drug carriers and find answers as to why this class of compounds…”
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Theranostics: Are We There Yet? by Svenson, Sonke

“…The U.S. National Institutes of Health through the National Cancer Institute (NCI) have been charged with the goal of eliminating death and suffering from…”
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Clinical translation of nanomedicines by Svenson, Sonke

“…► Nanotechnology has been successfully applied to medicine (nanomedicines). ► Twelve nanomedicine products are on the market, the majority (eight) based on the…”
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What nanomedicine in the clinic right now really forms nanoparticles? by Svenson, Sonke

“…Some researchers believe nanomedicine will revolutionize healthcare and medicine through transformative new therapeutic tools. Nanocarriers, utilized to…”
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Self-Assembly and Self-Organization: Important Processes, But Can We Predict Them? by Svenson, Sönke

“…Two aggregation processes of amphiphilic molecules, i.e., molecules consisting of a hydrophilic head group and a hydrophobic tail, are presented. Self-assembly…”
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Dendrimers as versatile platform in drug delivery applications by Svenson, Sonke

“…About forty percent of newly developed drugs are rejected by the pharmaceutical industry and will never benefit a patient because of poor bioavailability due…”
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Preclinical to clinical development of the novel camptothecin nanopharmaceutical CRLX101 by Svenson, Sonke, Wolfgang, Marc, Hwang, Jungyeon, Ryan, John, Eliasof, Scott

“…Camptothecin (CPT) is a potent broad-spectrum anticancer agent that acts through inhibition of topoisomerase 1. Clinical development of CPT was unsuccessful…”
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Dendrimers for enhanced drug solubilization by Svenson, Sonke, Chauhan, Abhay S

“…Approximately 40% of newly developed drugs are rejected by the pharmaceutical industry and will never benefit a patient because of low water solubility…”
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Dendrimers as versatile platform in drug delivery applications: Engineered Polymers in controlled drug delivery and targeting by SVENSON, Sonke

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Discovery of a Novel Cabazitaxel Nanoparticle–Drug Conjugate (CRLX522) with Improved Pharmacokinetic Properties and Anticancer Effects Using a β‑Cyclodextrin–PEG Copolymer Based Delivery Platform by Metcalf, Chester A, Svenson, Sonke, Hwang, Jungyeon, Tripathi, Snehlata, Gangal, Geeti, Kabir, Sujan, Lazarus, Douglas, Cole, Roderic, Sweryda-Krawiec, Beata, Shum, Pochi, Brown, Donna, Case, Roy I, van der Poll, Derek, Rohde, Ellen, Harlfinger, Stephanie, Teng, Chi-Hse, Eliasof, Scott

“…Novel nanoparticle–drug conjugates (NDCs) containing diverse, clinically relevant anticancer drug payloads (docetaxel, cabazitaxel, and gemcitabine) were…”
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Tumor Selective Silencing Using an RNAi-Conjugated Polymeric Nanopharmaceutical by Svenson, Sonke, Case, Roy I, Cole, Roderick O, Hwang, Jungyeon, Kabir, Sujan R, Lazarus, Douglas, Lim Soo, Patrick, Ng, Pei-Sze, Peters, Christian, Shum, Pochi, Sweryda-Krawiec, Beata, Tripathi, Snehlata, van der Poll, Derek, Eliasof, Scott

“…Small interfering RNA (siRNA) therapeutics have potential advantages over traditional small molecule drugs such as high specificity and the ability to inhibit…”
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Controlling surfactant self-assembly by Svenson, Sönke

“…Spontaneous self-assembly of surfactants in water to form vesicles has been reviewed, starting from the hypothesis that monomer solubility rather then packing…”
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Bolaamphiphilic Phosphocholines:  Structure and Phase Behavior in Aqueous Media by Meglio, Ciro Di, Rananavare, Shankar B, Svenson, Sönke, Thompson, David H

“…The phase behavior of 1,1‘-di-O-eicosamethylene-2,2‘-di-O-decylbis(glycero-3-phosphocholine) (1) and…”
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Long-lived micellar N-alkylaldonamide fiber gels. Solid-state NMR and electron microscopic studies by Fuhrhop, Juergen Hinrich, Svenson, Soenke, Boettcher, Christoph, Roessler, Ernst, Vieth, Hans Martin

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Formation of Polymerizable Phospholipid Nanotubules and Their Transformation into a Network Gel by Svenson, Sönke, Messersmith, Phillip B

“…Phospholipids containing diacetylene moieties along their hydrocarbon chains have been extensively studied for their ability to self-assemble into tubule…”
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Facile and Efficient Synthesis of Bolaamphiphilic Tetraether Phosphocholines by Svenson, Sönke, Thompson, David H

“…A facile synthesis of ether-linked bolaform phospholipids in good yields has been developed. Triflic acid catalyzed oxirane ring opening of benzyl-protected…”
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Rearrangements of N-Octyl-d-gluconamide Fibers and Bilayers on Gold and Silicon Surfaces by Messerschmidt, Christian, Svenson, Sönke, Stocker, Wolfgang, Fuhrhop, Jürgen-Hinrich

“…N-Octyl-d-gluconamide (1) is known to form noncovalent quadruple helices in bulk aqueous media. Upon adsorption to mica these fibers survive; on gold they…”
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Non-covalent chiral fibres in aqueous gels and their functionalization by Fuhrhop, Jürgen-Hinrich, Svenson, Sönke, Böttcher, Christoph, Träger, Otto, Demoulin, Corinna, Schnieder, Peter, Messerschmidt, Christian, Ruhlmann, Laurent, Zimmermann, Jörg

“…The fully reversible synthesis of noncovalent assemblies which are held together by directed bonds is called synkinesis. Micellar fibres with a distinct…”
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