Search Results - "Svendsen, Samuel L"

Secretin: a hormone for HCO3− homeostasis by Berg, Peder, Svendsen, Samuel L., Ayasse, Niklas, Sorensen, Mads Vaarby, Leipziger, Jens

“…Secretin is a key hormone of the intestinal phase of digestion which activates pancreatic, bile duct and Brunner gland HCO 3 − secretion. Recently, the…”
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The molecular mechanism of CFTR‐ and secretin‐dependent renal bicarbonate excretion by Berg, Peder, Svendsen, Samuel L., Sorensen, Mads Vaarby, Schreiber, Rainer, Kunzelmann, Karl, Leipziger, Jens

“…This review summarizes the newly discovered molecular mechanism of secretin‐stimulated urine HCO3– excretion and the role of cystic fibrosis transmembrane…”
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Impaired Renal HCO3 - Excretion in Cystic Fibrosis by Berg, Peder, Svendsen, Samuel L., Sorensen, Mads V., Larsen, Casper K., Andersen, Jesper Frank, Jensen-Fangel, Søren, Jeppesen, Majbritt, Schreiber, Rainer, Cabrita, Ines, Kunzelmann, Karl, Leipziger, Jens

“…BACKGROUNDPatients with cystic fibrosis (CF) do not respond with increased urinary HCO3 - excretion after stimulation with secretin and often present with…”
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Impaired renal HCO3− secretion in CFTR deficient mice causes metabolic alkalosis during chronic base‐loading by Berg, Peder, Svendsen, Samuel L., Hoang, Thi Thuy Linh, Praetorius, Helle A., Sorensen, Mads V., Leipziger, Jens

“…Aim Cystic fibrosis patients have an increased risk of developing metabolic alkalosis presumably as a result of altered renal HCO3− handling. In this study, we…”
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Loss of the Secretin Receptor Impairs Renal Bicarbonate Excretion and Aggravates Metabolic Alkalosis in Mice during Acute Base-Loading by Berg, Peder, Jensen, Tobias, Andersen, Jesper Frank, Svendsen, Samuel L, Modvig, Ida Maria, Wang, Tobias, Frische, Sebastian, Chow, Billy K C, Malte, Hans, Holst, Jens Juul, Sørensen, Mads Vaarby, Leipziger, Jens

“…During acute base excess, the renal collecting duct β -intercalated cells ( β -ICs) become activated to increase urine base excretion. This process is…”
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Unrecognized role of claudin‐10b in basolateral membrane infoldings of the thick ascending limb by Quintanova, Catarina, Himmerkus, Nina, Svendsen, Samuel L., Schwerdtner, Otto, Merkel, Cosima, Pinckert, Lennart, Mutig, Kerim, Breiderhoff, Tilman, Müller, Dominik, Günzel, Dorothee, Bleich, Markus

“…Claudin‐10b is an important component of the tight junction in the thick ascending limb (TAL) of Henle's loop and allows paracellular sodium transport. In…”
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Impaired renal HCO 3 - secretion in CFTR deficient mice causes metabolic alkalosis during chronic base-loading by Berg, Peder, Svendsen, Samuel L, Hoang, Thi Thuy Linh, Praetorius, Helle A, Sorensen, Mads V, Leipziger, Jens

“…Cystic fibrosis patients have an increased risk of developing metabolic alkalosis presumably as a result of altered renal HCO handling. In this study, we…”
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Dietary K+ acts as a genuine diuretic by Svendsen, Samuel L., Kornvig, Simon, Berg, Peder, Jensen, Iben S., Araujo, Isabela B. B. A., Larsen, Casper K., Leipziger, Jens, Sørensen, Mads V.

“…K+ balance in mammals relies on regulated renal K+ excretion matching unregulated fluctuating K+ intake. Upon a K+ rich meal, rapid and powerful K+ excretion…”
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P2X Receptors Inhibit NaCl Absorption in mTAL Independently of Nitric Oxide by Svendsen, Samuel L, Isidor, Søren, Praetorius, Helle A, Leipziger, Jens

“…Activation of basolateral P2X receptors markedly reduces NaCl absorption in mouse medullary thick ascending limb (mTAL). Here we tested the role of nitric…”
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Viewing Cortical Collecting Duct Function Through Phenotype-guided Single-Tubule Proteomics by Himmerkus, Nina, Svendsen, Samuel L, Quintanova, Catarina, Bleich, Markus, Von Schwerdtner, Otto, Benzing, Thomas, Welling, Paul A, Leipziger, Jens, Rinschen, Markus M

“…The revolution of the omics technologies has enabled profiling of the molecules of any sample. However, the heterogeneity of the kidney with highly specialized…”
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Changes in Renal Acid-Base Handling in Megalin-Knockout Mice: FR-PO504 by Klahn, Peter A., Berg, Peder, Sorensen, Mads V., Weyer, Kathrin, Svendsen, Samuel L., Leipziger, Jens G., Nielsen, Rikke

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ENaC Inhibition with Trimethoprim Occurs Without Changing Urinary H+ Excretion: FR-OR30 by Ayasse, Niklas, Berg, Peder, Svendsen, Samuel L., Rousing, Amalie Q., Sorensen, Mads V., Fedosova, Natalya U., Leipziger, Jens G.

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Subclinical Acidosis Assessed by a New Urine Acid-Base Score Is an Independent Risk Factor for CKD Progression: FR-PO1086 by Svendsen, Samuel L., Carlsen, Rasmus, Buus, Niels H., Birn, Henrik, Leipziger, Jens G., Berg, Peder, Sorensen, Mads V.

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The AE4 (Slc4a9) Transporter Is Essential for Renal Acid-Base Sensing: TH-PO309 by Vitzthum, Helga, Koch, Mirijam, Eckermann, Leya, Svendsen, Samuel L., Berg, Peder, Dreger, Kimberley, Hübner, Christian A., Wagner, Carsten A., Leipziger, Jens G., Meyer-Schwesinger, Catherine, Ehmke, Heimo

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Secretin: a hormone for HCO 3 - homeostasis by Berg, Peder, Svendsen, Samuel L, Ayasse, Niklas, Sorensen, Mads Vaarby, Leipziger, Jens

“…Secretin is a key hormone of the intestinal phase of digestion which activates pancreatic, bile duct and Brunner gland HCO secretion. Recently, the secretin…”
Get full text

Impaired Renal HCO 3 - Excretion in Cystic Fibrosis by Berg, Peder, Svendsen, Samuel L, Sorensen, Mads V, Larsen, Casper K, Andersen, Jesper Frank, Jensen-Fangel, Søren, Jeppesen, Majbritt, Schreiber, Rainer, Cabrita, Ines, Kunzelmann, Karl, Leipziger, Jens

“…Patients with cystic fibrosis (CF) do not respond with increased urinary HCO excretion after stimulation with secretin and often present with metabolic…”
Get full text