Search Results - "Svelto, M"

Intercellular crosstalk mediated by tunneling nanotubes between central nervous system cells. What we need to advance by Capobianco, D L, Simone, L, Svelto, M, Pisani, F

“…Long-range intercellular communication between Central Nervous System (CNS) cells is an essential process for preserving CNS homeostasis. Paracrine signaling,…”
Get full text

Human neural stem cells derived from fetal human brain communicate with each other and rescue ischemic neuronal cells through tunneling nanotubes by Capobianco, D. L., De Zio, R., Profico, D. C., Gelati, M., Simone, L., D’Erchia, A. M., Di Palma, F., Mormone, E., Bernardi, P., Sbarbati, A., Gerbino, A., Pesole, G., Vescovi, A. L., Svelto, M., Pisani, F.

“…Pre-clinical trials have demonstrated the neuroprotective effects of transplanted human neural stem cells (hNSCs) during the post-ischemic phase. However, the…”
Get full text

Gut microbiota and fecal volatilome profile inspection in metabolically healthy and unhealthy obesity phenotypes by Calabrese, F. M., Genchi, V. A., Serale, N., Celano, G., Vacca, M., Palma, G., Svelto, M., Gesualdo, L., De Angelis, M., Giorgino, F., Perrini, S.

“…Background People with metabolically healthy (MHO) and metabolically unhealthy obesity (MUO) differ for the presence or absence of cardio-metabolic…”
Get full text

Reduced hepatic aquaporin-9 and glycerol permeability are related to insulin resistance in non-alcoholic fatty liver disease by Rodríguez, A, Gena, P, Méndez-Giménez, L, Rosito, A, Valentí, V, Rotellar, F, Sola, I, Moncada, R, Silva, C, Svelto, M, Salvador, J, Calamita, G, Frühbeck, G

“…Background/Objectives: Glycerol represents an important metabolite for the control of lipid accumulation and hepatic gluconeogenesis. We investigated whether…”
Get full text

GFAP serves as a structural element of tunneling nanotubes between glioblastoma cells and could play a role in the intercellular transfer of mitochondria by Simone, L., Capobianco, D. L., Di Palma, F., Binda, E., Legnani, F. G., Vescovi, A. L., Svelto, M., Pisani, F.

“…Tunneling nanotubes (TNTs) are long F-actin-positive plasma membrane bridges connecting distant cells, allowing the intercellular transfer of cellular cargoes,…”
Get full text

Simvastatin increases AQP2 urinary excretion in hypercholesterolemic patients: A pleiotropic effect of interest for patients with impaired AQP2 trafficking by Procino, G, Portincasa, P, Mastrofrancesco, L, Castorani, L, Bonfrate, L, Addabbo, F, Carmosino, M, Di Ciaula, A, Svelto, M

“…We previously reported that statins improve the symptoms of X‐linked nephrogenic diabetes insipidus (X‐NDI) in animal models. The aim of this study was to…”
Get full text

Cell culture models and animal models for studying the patho-physiological role of renal aquaporins by Tamma, G., Procino, G., Svelto, M., Valenti, G.

“…Aquaporins (AQPs) are key players regulating urinary-concentrating ability. To date, eight aquaporins have been characterized and localized along the nephron,…”
Get full text

The role of aquaporin-4 in the blood–brain barrier development and integrity: Studies in animal and cell culture models by Nicchia, G.P., Nico, B., Camassa, L.M.A., Mola, M.G., Loh, N., Dermietzel, R., Spray, D.C., Svelto, M., Frigeri, A.

“…Aquaporin-4 (AQP4) is the major water channel expressed in brain perivascular astrocyte processes. Although the role of AQP4 in brain edema has been…”
Get full text

The Inner Mitochondrial Membrane Has Aquaporin-8 Water Channels and Is Highly Permeable to Water by Calamita, Giuseppe, Ferri, Domenico, Gena, Patrizia, Liquori, Giuseppa E., Cavalier, Annie, Thomas, Daniel, Svelto, Maria

“…Mitochondria are remarkably plastic organelles constantly changing their shape to fulfil their various functional activities. Although the osmotic movement of…”
Get full text

Functional characterization of a novel truncating mutation in Lamin A/C gene in a family with a severe cardiomyopathy with conduction defects by Gerbino, A., Bottillo, I., Milano, S., De Zio, R., Procino, G., Grammatico, P., Svelto, M., Carmosino, M.

“…Objective: Truncating LMNA gene mutations occur in many inherited cardiomyopathy cases, but the molecular mechanisms involved in the disease they cause have…”
Get full text

Lovastatin-induced cholesterol depletion affects both apical sorting and endocytosis of aquaporin-2 in renal cells by Procino, G, Barbieri, C, Carmosino, M, Rizzo, F, Valenti, G, Svelto, M

“…Vasopressin causes the redistribution of the water channel aquaporin-2 (AQP2) from cytoplasmic storage vesicles to the apical plasma membrane of collecting…”
Get more information

Higher order structure of aquaporin-4 by Nicchia, G.P, Rossi, A, Mola, M.G, Pisani, F, Stigliano, C, Basco, D, Mastrototaro, M, Svelto, M, Frigeri, A

“…Abstract Unlike other mammalian AQPs, multiple tetramers of AQP4 associate in the plasma membrane to form peculiar structures called Orthogonal Arrays of…”
Get full text

Aquaporins in the hepatobiliary tract. Which, where and what they do in health and disease by Portincasa, P., Palasciano, G., Svelto, M., Calamita, G.

“…ABSTRACT The biological importance of the aquaporin family of water channels was recently acknowledged by the 2003 Nobel Prize for Chemistry awarded to the…”
Get full text

D184E mutation in aquaporin-4 gene impairs water permeability and links to deafness by Nicchia, G.P, Ficarella, R, Rossi, A, Giangreco, I, Nicolotti, O, Carotti, A, Pisani, F, Estivill, X, Gasparini, P, Svelto, M, Frigeri, A

“…Abstract Aquaporins (AQPs) play a physiological role in several organs and tissues, and their alteration is associated with disorders of water regulation. The…”
Get full text

Serum and CSF N-acetyl aspartate levels differ in multiple sclerosis and neuromyelitis optica by Tortorella, C, Ruggieri, M, Di Monte, E, Ceci, E, Iaffaldano, P, Direnzo, V, Mastrapasqua, M, Frigeri, A, Amato, M P, Hakiki, B, Ghezzi, A, Lugaresi, A, De Luca, G, Patti, F, D'amico, E, Sola, P, Simone, A M, Svelto, M, Livrea, P, Trojano, M

“…BackgroundThe identification of biomarkers able to improve the differential diagnosis between multiple sclerosis (MS) and neuromyelitis optica (NMO) is…”
Get full text

Aquaporin‐4 deficiency in skeletal muscle and brain of dystrophic mdx mice by FRIGERI, ANTONIO, NICCHIA, GRAZIA PAOLA, NICO, BEATRICE, QUONDAMATTEO, FABIO, HERKEN, RAINER, RONCALI, LUISA, SVELTO, MARIA

“…ABSTRACT We report a detailed study of AQP4 expression in the neuromuscular system of mdx mice. Immunocytochemical analysis performed by double immunostaining…”
Get full text

Molecular basis of constitutively active variants of the calcium-sensing receptor (CaSR) by Ranieri, M, Tamma, G, Di Mise, A, Vezzoli, G, Soldati, L, Svelto, M, Valenti, G

Get full text

Aquaporin 2 and Apical Calcium-Sensing Receptor: New Players in Polyuric Disorders Associated With Hypercalciuria by Procino, G., PhD, Mastrofrancesco, L, Mira, A., PhD, Tamma, G., PhD, Carmosino, M., PhD, Emma, F., MD, Svelto, M., PhD, Valenti, G., PhD

“…Summary The kidney plays a critical role in regulating water homeostasis through specific proteins highly expressed in the kidney, called aquaporins , allowing…”
Get full text

Aquaporin-2 urinary excretion in preterm infants: relationship to diuresis and vasopressin by Iacobelli, S., Gouyon, J.B., Bonsante, F., Mastrofrancesco, L., Svelto, M., Valenti, G.

“…Aims:  Few investigations have explored the urinary aquaporin‐2 (u‐AQP2) excretion pattern after birth in preterm infants with conflicting results regarding…”
Get full text

Effects of chronic treatment with statins and fenofibrate on rat skeletal muscle: a biochemical, histological and electrophysiological study by Pierno, S, Didonna, M P, Cippone, V, Luca, A, Pisoni, M, Frigeri, A, Nicchia, G P, Svelto, M, Chiesa, G, Sirtori, C, Scanziani, E, Rizzo, C, Vito, D, Conte Camerino, D

“…Background and purpose: Skeletal muscle injury by hypolipidemic drugs is not fully understood. An extensive analysis of the effect of chronic treatment with…”
Get full text