Search Results - "Sveen, A"

Aberrant RNA splicing in cancer; expression changes and driver mutations of splicing factor genes by Sveen, A, Kilpinen, S, Ruusulehto, A, Lothe, R A, Skotheim, R I

“…Alternative splicing is a widespread process contributing to structural transcript variation and proteome diversity. In cancer, the splicing process is…”
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Relative contribution of clinicopathological variables, genomic markers, transcriptomic subtyping and microenvironment features for outcome prediction in stage II/III colorectal cancer by Dienstmann, R., Villacampa, G., Sveen, A., Mason, M.J., Niedzwiecki, D., Nesbakken, A., Moreno, V., Warren, R.S., Lothe, R.A., Guinney, J.

“…It remains unknown to what extent consensus molecular subtype (CMS) groups and immune-stromal infiltration patterns improve our ability to predict outcomes…”
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Prediction of overall survival in stage II and III colon cancer beyond TNM system: a retrospective, pooled biomarker study by Dienstmann, R., Mason, M.J., Sinicrope, F.A., Phipps, A.I., Tejpar, S., Nesbakken, A., Danielsen, S.A., Sveen, A., Buchanan, D.D., Clendenning, M., Rosty, C., Bot, B., Alberts, S.R., Milburn Jessup, J., Lothe, R.A., Delorenzi, M., Newcomb, P.A., Sargent, D., Guinney, J.

“…TNM staging alone does not accurately predict outcome in colon cancer (CC) patients who may be eligible for adjuvant chemotherapy. It is unknown to what extent…”
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Predictive modeling in colorectal cancer: time to move beyond consensus molecular subtypes by Sveen, A., Cremolini, C., Dienstmann, R.

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Societal costs of personality disorders among treatment-seeking patients in Norway: the relative contribution of specific DSM-5 categories by Sveen, C. A., Pedersen, G., Ulvestad, D. A., Zahl, K. E., Wilberg, T., Kvarstein, E. H.

“…Personality disorders (PDs) are associated with high levels of societal costs, regardless of whether a single PD or a broad range of PDs have been studied…”
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N-terminal pro-B-type natriuretic peptide levels vary by ethnicity and are associated with insulin sensitivity after gestational diabetes mellitus by Sharma, Archana, Birkeland, Kåre I, Nermoen, Ingrid, Sommer, Christine, Qvigstad, Elisabeth, Lee-Ødegård, Sindre, Sveen, Kari A, Sattar, Naveed, Sollid, Stina T, Omland, Torbjørn, Myhre, Peder L

“…Individuals of South Asian origin have a greater risk of cardiovascular disease after gestational diabetes mellitus (GDM) than European individuals. B-type…”
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CMS-dependent prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer by Smeby, J., Sveen, A., Merok, M.A., Danielsen, S.A., Eilertsen, I.A., Guren, M.G., Dienstmann, R., Nesbakken, A., Lothe, R.A.

“…The prognostic impact of KRAS and BRAFV600E mutations in primary colorectal cancer (CRC) varies with microsatellite instability (MSI) status. The gene…”
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461: Genomic copy number and microRNA profiles of 27 colon cancer cell lines by Berg, K.G, Eide, P.W, Eilertsen, I.A, Cekaite, L, Sveen, A, Lothe, R.A

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Heterologous protein secretion by Lactobacillus plantarum using homologous signal peptides by Mathiesen, G, Sveen, A, Piard, J.-C, Axelsson, L, Eijsink, V.G.H

“…To test seven selected putative signal peptides from Lactobacillus plantarum WCFS1 in terms of their ability to drive secretion of two model proteins in Lact…”
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PO-505 Prognostic impact of KRAS splicing in microsatellite stable colorectal cancer by Eilertsen, IA, Sveen, A, Hektoen, M, Strømme, JM, Johannessen, B, Skotheim, RI, Nesbakken, A, Lothe, RA

“…IntroductionMutations in the KRAS oncogene represent one of the most common genetic alterations in colorectal cancer (CRC). KRAS is expressed as two transcript…”
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PO-325 Novel recurrent high-level amplifications in microsatellite stable colorectal cancer by Berg, KCG, Sveen, A, Høland, M, Berg, M, Hektoen, M, Alagaratnam, S, Nesbakken, A, Søreide, K, Lothe, RA

“…IntroductionColorectal cancer (CRC) is a molecularly diverse disease with few targeted treatment options. Focal and high-amplitude DNA copy number aberrations…”
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PO-127 Role of the NEDD4 family of E3 ubiquitin ligases in colorectal cancer pathogenesis and their potential as biomarkers by Knudsen, LM, Sveen, A, Bergsland, CH, Five, MB, Rasmussen, NL, Totland, MZ, Eide, PW, Bruun, J, Lothe, RA, Leithe, E

“…IntroductionColorectal cancer (CRC) is a global health challenge. There is limited response to standard oncological treatment and few stratified treatment…”
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Societal costs of personality disorders: A cross‐sectional multicenter study of treatment‐seeking patients in mental health services in Norway by Sveen, C. A., Pedersen, G., Ulvestad, D. A., Zahl, K. E., Wilberg, T., Kvarstein, E. H.

“…Objective There is a relatively small body of research on the cost‐of‐illness of personality disorders (PDs). Most studies only include borderline PD. The aim…”
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882 New insights into molecular pathways of colorectal cancer from genome-level expression data by Cekaite, L, Danielsen, S.A, Ågesen, T.H, Sveen, A, Thiis-Evensen, E, Merok, A.M, Nesbakken, A, Skotheim, R.I, Lothe, R.A

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Colorectal Cancer Consensus Molecular Subtypes Translated to Preclinical Models Uncover Potentially Targetable Cancer Cell Dependencies by Sveen, Anita, Bruun, Jarle, Eide, Peter W, Eilertsen, Ina A, Ramirez, Lorena, Murumägi, Astrid, Arjama, Mariliina, Danielsen, Stine A, Kryeziu, Kushtrim, Elez, Elena, Tabernero, Josep, Guinney, Justin, Palmer, Hector G, Nesbakken, Arild, Kallioniemi, Olli, Dienstmann, Rodrigo, Lothe, Ragnhild A

“…Response to standard oncologic treatment is limited in colorectal cancer. The gene expression-based consensus molecular subtypes (CMS) provide a new paradigm…”
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344P Tumor organoids from multifocal metastatic colorectal cancers for personalized oncology by Kryeziu, K., Berg, K.C.G., Totland, M.Z., Moosavi, S.H., Niederdorfer, B., Klokkerud, S.K., Bergsland, C.H., Guren, T.K.K., Lassen, K., Nesbakken, A., Yaqub, S., Sveen, A., Lothe, R.A.

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Predictive modeling in colorectal cancer: time to move beyond consensus molecular subtypes by Sveen, A, Cremolini, C, Dienstmann, R

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SO-35 Tumor infiltrating CD3 lymphocytes and CD68 macrophages are associated with long-time survival in metastatic colorectal cancer patients treated with chemotherapy by Aasebø, K., Bruun, J., Bergsland, C., Eide, G., Dragomir, A., Ponten, F., Guren, M., Svindland, A., Pfeiffer, P., Glimelius, B., Sveen, A., Nesbakken, A., Lothe, R., Sorbye, H.

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Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer by Bruun, Jarle, Sveen, Anita, Barros, Rita, Eide, Peter W., Eilertsen, Ina, Kolberg, Matthias, Pellinen, Teijo, David, Leonor, Svindland, Aud, Kallioniemi, Olli, Guren, Marianne G., Nesbakken, Arild, Almeida, Raquel, Lothe, Ragnhild A.

“…We aimed to refine the value of CDX2 as an independent prognostic and predictive biomarker in colorectal cancer (CRC) according to disease stage and…”
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Prognostic impact of BRAF and KRAS mutations according to the consensus molecular subtypes of colorectal cancer by Smeby, J., Sveen, A., Bergsland, C.H., Bruun, J., Merok, M., Danielsen, S.A., Hektoen, M., Eknæs, M., Eilertsen, I.A., Grønlie Guren, M., Nesbakken, A., Lothe, R.A.

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