Search Results - "Svadlenka, Jan"
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Multifunctional adaptor protein Daxx interacts with chromatin-remodelling ATPase Brg1
Published in Biochemistry and biophysics reports (01-03-2016)“…Multifunctional adapter and chaperone protein Daxx participates in the regulation of a number of mainly transcription-related processes. Most notably in a…”
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TRAIL induces apoptosis but not necroptosis in colorectal and pancreatic cancer cells preferentially via the TRAIL-R2/DR5 receptor
Published in Biochimica et biophysica acta. Molecular cell research (01-03-2018)“…Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a cytokine that can trigger apoptosis in many types of human cancer cells via engagement of…”
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DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase
Published in Cell cycle (Georgetown, Tex.) (01-02-2015)“…Death domain-associated protein 6 (DAXX) is a histone chaperone, putative regulator of apoptosis and transcription, and candidate modulator of p53-mediated…”
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Targeting of BCL2 Family Proteins with ABT-199 and Homoharringtonine Reveals BCL2- and MCL1-Dependent Subgroups of Diffuse Large B-Cell Lymphoma
Published in Clinical cancer research (01-03-2016)“…To investigate the roles of BCL2, MCL1, and BCL-XL in the survival of diffuse large B-cell lymphoma (DLBCL). Immunohistochemical analysis of 105 primary DLBCL…”
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Inhibition of vacuolar ATPase attenuates the TRAIL‐induced activation of caspase‐8 and modulates the trafficking of TRAIL receptosomes
Published in The FEBS journal (01-07-2013)“…Tumour necrosis factor (TNF) related apoptosis inducing ligand (TRAIL), a membrane‐bound ligand from the TNF family, has attracted significant attention due to…”
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MCL1 Targeting Agent Homoharringtonine Exerts Strong Cytotoxicity Towards Diffuse Large B-Cell Lymphoma (DLBCL) Cells and Synergizes with BCL2 Targeting Agent ABT199 in Eliminating BCL2-Positive DLBCL Cells
Published in Blood (06-12-2014)“…Introduction: Diffuse large B-cell lymphoma (DLBCL) represents the most prevalent type of B-cell non-Hodgkin lymphomas (B-NHL) in the Western hemisphere. While…”
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Inhibition of vacuolar ATP ase attenuates the TRAIL ‐induced activation of caspase‐8 and modulates the trafficking of TRAIL receptosomes
Published in The FEBS journal (01-07-2013)Get full text
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8
DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase
Published in Cell Cycle (01-02-2015)“…Death domain-associated protein 6 (DAXX) is a histone chaperone, putative regulator of apoptosis and transcription, and candidate modulator of p53-mediated…”
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