Search Results - "Svärd, J"

Genetic Elimination of Suppressor of Fused Reveals an Essential Repressor Function in the Mammalian Hedgehog Signaling Pathway by Svärd, Jessica, Henricson, Karin Heby, Persson-Lek, Madelen, Rozell, Björn, Lauth, Matthias, Bergström, Åsa, Ericson, Johan, Toftgård, Rune, Teglund, Stephan

“…The Hedgehog (Hh) pathway plays important roles during embryogenesis and carcinogenesis. Here, we show that ablation of the mouse Suppressor of fused ( Sufu),…”
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Differential interactions of antiretroviral agents with LXR, ER and GR nuclear receptors: potential contributing factors to adverse events by Svärd, J, Blanco, F, Nevin, D, Fayne, D, Mulcahy, F, Hennessy, M, Spiers, J P

“…Background and Purpose Antiretroviral (ARV) drugs activate pregnane X receptors and constitutive androstane receptors, increasing the risk of drug interactions…”
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Tumor-specific expression of the novel cytochrome P450 enzyme, CYP2W1 by Karlgren, Maria, Gomez, Alvin, Stark, Katarina, Svärd, Jenny, Rodriguez-Antona, Cristina, Oliw, Ernst, Bernal, Maria Luisa, y Cajal, Santiago Ramón, Johansson, Inger, Ingelman-Sundberg, Magnus

“…A novel human cytochrome P450, CYP2W1, was cloned and expressed heterologously. No or very low CYP2W1 mRNA levels were detected in fetal and adult human…”
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Distinct roles of first exon variants of the tumor-suppressor Patched1 in Hedgehog signaling by Shimokawa, T, Svärd, J, Heby-Henricson, K, Teglund, S, Toftgård, R, Zaphiropoulos, P G

“…Patched1 (PTCH1) is one of the key molecules involved in the Hedgehog (HH) signaling pathway and acts as the receptor of HH ligands. Additionally, PTCH1…”
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Genetic Elimination of Suppressor of Fused Reveals an Essential Repressor Function in the Mammalian Hedgehog Signaling Pathway by Svärd, Jessica, Heby-Henricson, Karin, Persson-Lek, Madelen, Rozell, Björn, Lauth, Matthias, Bergström, Åsa, Ericson, Johan, Toftgård, Rune, Teglund, Stephan

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Gut microbiota diversity predicts immune status in HIV-1 infection by Nowak, Piotr, Troseid, Marius, Avershina, Ekatarina, Barqasho, Babilonia, Neogi, Ujjwal, Holm, Kristian, Hov, Johannes R, Noyan, Kajsa, Vesterbacka, Jan, Svärd, Jenny, Rudi, Knut, Sönnerborg, Anders

“…OBJECTIVE:HIV-1 infection is characterized by altered intestinal barrier, gut microbiota dysbiosis, and systemic inflammation. We hypothesized that changes of…”
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Association between polymorphisms in NOS3 and KCNH2 and social memory by Henningsson, Susanne, Zettergren, Anna, Hovey, Daniel, Jonsson, Lina, Svärd, Joakim, Cortes, Diana S, Melke, Jonas, Ebner, Natalie C, Laukka, Petri, Fischer, Håkan, Westberg, Lars

“…Social memory, including the ability to recognize faces and voices, is essential for social relationships. It has a large heritable component, but the…”
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Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection by Leeansyah, Edwin, Svärd, Jenny, Dias, Joana, Buggert, Marcus, Nyström, Jessica, Quigley, Máire F, Moll, Markus, Sönnerborg, Anders, Nowak, Piotr, Sandberg, Johan K

“…Mucosa-associated invariant T (MAIT) cells represent a large innate-like evolutionarily conserved antimicrobial T-cell subset in humans. MAIT cells recognize…”
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Distinct roles of first exon variants of the tumor-suppressor patchedl in hedgehog signaling by SHIMOKAWA, T, SVÄRD, J, HEBY-HENRICSON, K, TEGLUND, S, TOFTGARD, R, ZAPHIROPOULOS, P. G

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Multiparametric bioinformatics distinguish the CD4/CD8 ratio as a suitable laboratory predictor of combined T cell pathogenesis in HIV infection by Buggert, Marcus, Frederiksen, Juliet, Noyan, Kajsa, Svärd, Jenny, Barqasho, Babilonia, Sönnerborg, Anders, Lund, Ole, Nowak, Piotr, Karlsson, Annika C

“…HIV disease progression is characterized by numerous pathological changes of the cellular immune system. Still, the CD4 cell count and viral load represent the…”
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Drug resistance testing through remote genotyping and predicted treatment options in human immunodeficiency virus type 1 infected Tanzanian subjects failing first or second line antiretroviral therapy by Svärd, Jenny, Mugusi, Sabina, Mloka, Doreen, Neogi, Ujjwal, Meini, Genny, Mugusi, Ferdinand, Incardona, Francesca, Zazzi, Maurizio, Sönnerborg, Anders

“…Antiretroviral therapy (ART) has been successfully introduced in low-middle income countries. However an increasing rate of ART failure with resistant virus is…”
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Patients With Parkinson's Disease Display a Dopamine Therapy Related Negative Bias and an Enlarged Range in Emotional Responses to Facial Emotional Stimuli by Lundqvist, Daniel, Svärd, Joakim, Michelgård Palmquist, Åsa, Fischer, Håkan, Svenningsson, Per

“…Objective: The literature on emotional processing in Parkinson's disease (PD) patients shows mixed results. This may be because of various methodological…”
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Face gender modulates women's brain activity during face encoding by Lovén, Johanna, Svärd, Joakim, Ebner, Natalie C, Herlitz, Agneta, Fischer, Håkan

“…Women typically remember more female than male faces, whereas men do not show a reliable own-gender bias. However, little is known about the neural correlates…”
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Role of translocated bacterial flagellin in monocyte activation among individuals with chronic HIV-1 infection by Svärd, Jenny, Paquin-Proulx, Dominic, Buggert, Marcus, Noyan, Kajsa, Barqasho, Babilonia, Sönnerborg, Anders, Nowak, Piotr

“…Abstract Monocyte activation has been identified as a predictor of mortality and morbidity in HIV-1 infection. This study investigated translocated bacterial…”
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On the Usefulness of Circulating Bacterial 16S rDNA as a Marker of Microbial Translocation in HIV-1–Infected Patients by Svärd, Jenny, Sönnerborg, Anders, Vondracek, Martin, Mölling, Paula, Nowak, Piotr

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Variation in the Oxytocin Receptor Gene Is Associated with Face Recognition and its Neural Correlates by Westberg, Lars, Henningsson, Susanne, Zettergren, Anna, Svärd, Joakim, Hovey, Daniel, Lin, Tian, Ebner, Natalie C, Fischer, Håkan

“…The ability to recognize faces is crucial for daily social interactions. Recent studies suggest that intranasal oxytocin administration improves social…”
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Superior recognition performance for happy masked and unmasked faces in both younger and older adults by Svärd, Joakim, Wiens, Stefan, Fischer, Håkan

“…In the aging literature it has been shown that even though emotion recognition performance decreases with age, the decrease is less for happiness than other…”
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Selection of pfmdr1 mutations after amodiaquine monotherapy and amodiaquine plus artemisinin combination therapy in East Africa by Holmgren, Gabrielle, Hamrin, Johan, Svärd, Jenny, Mårtensson, Andreas, Gil, José Pedro, Björkman, Anders

“…Despite the pharmacodynamic advantages with artemisinin-based combination therapy (ACT) and some potentially opposite molecular mechanisms of tolerance to…”
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PERSONALITY AND CHANGE IN COGNITIVE FUNCTION OVER 9 YEARS: THE ROLE OF MARITAL STATUS by Wang, H, Svard, J, Fisher, H

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Adult age-differences in subjective impression of emotional faces are reflected in emotion-related attention and memory tasks by Svärd, Joakim, Fischer, Håkan, Lundqvist, Daniel

“…Although younger and older adults appear to attend to and remember emotional faces differently, less is known about age-related differences in the subjective…”
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