Search Results - "Suzuki, Motoshi"
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Proceedings of the 53rd Annual Meeting of Fujita Medical Society
Published in Fujita Medical Journal (2022)Get full text
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A method for extracting sole mechanical properties of Bragg reflector by GHz ultrasonic pulse-echo technique
Published in Applied physics letters (31-10-2022)“…Solidly mounted resonators (SMRs) with an acoustic Bragg reflector should be more suitable for high power RF filters than a self-standing structure because…”
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Inhibition of heat shock protein 90 destabilizes receptor tyrosine kinase ROR1 in lung adenocarcinoma
Published in Cancer science (01-03-2021)“…We have previously identified receptor tyrosine kinase‐like orphan receptor 1 (ROR1) as a direct transcriptional target of TTF‐1/NKX2‐1, a lineage‐survival…”
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Long non-coding RNA TILR constitutively represses TP53 and apoptosis in lung cancer
Published in Oncogene (27-01-2023)“…Non-coding RNAs have an integral regulatory role in numerous functions related to lung cancer development. Here, we report identification of a novel lncRNA,…”
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Thyroid transcription factor‐1‐regulated microRNA‐532‐5p targets KRAS and MKL2 oncogenes and induces apoptosis in lung adenocarcinoma cells
Published in Cancer science (01-07-2017)“…Thyroid transcription factor‐1 (TTF‐1), also known as NKX2‐1, plays a role as a lineage‐survival oncogene in lung adenocarcinoma that possesses double‐edged…”
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ROR1-CAVIN3 interaction required for caveolae-dependent endocytosis and pro-survival signaling in lung adenocarcinoma
Published in Oncogene (01-06-2019)“…The receptor tyrosine kinase-like orphan receptor 1 (ROR1) is a transcriptional target of the lineage-survival oncogene NKX2–1/TTF-1 in lung adenocarcinomas…”
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BAX activation is initiated at a novel interaction site
Published in Nature (23-10-2008)“…BAX is a pro-apoptotic protein of the BCL-2 family that is stationed in the cytosol until activated by a diversity of stress stimuli to induce cell death…”
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ROR1 sustains caveolae and survival signalling as a scaffold of cavin-1 and caveolin-1
Published in Nature communications (04-01-2016)“…The receptor tyrosine kinase-like orphan receptor 1 (ROR1) sustains prosurvival signalling directly downstream of the lineage-survival oncogene NKX2-1/TTF-1 in…”
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Increased chemosensitivity via BRCA2-independent DNA damage in DSS1- and PCID2-depleted breast carcinomas
Published in Laboratory investigation (01-08-2021)“…Breast cancer, the most common malignancy among women, is closely associated with mutations in the tumor suppressor gene BRCA. DSS1, a component of the…”
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Mosaic gene expression analysis of semaphorin–plexin interactions in Caenorhabditis elegans using the IR‐LEGO single‐cell gene induction system
Published in Development, growth & differentiation (01-06-2022)“…Genetic mosaic analysis is a powerful means of addressing the sites of gene action in multicellular organisms. In conventional genetic analysis, the generation…”
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Mechanism of paclitaxel resistance in a human prostate cancer cell line, PC3-PR, and its sensitization by cabazitaxel
Published in Biochemical and biophysical research communications (28-10-2016)“…Paclitaxel (PTX) is a microtubule-targeting drug widely used for the treatment of a variety of cancers. However, drug resistance can emerge after a series of…”
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Role of the Yersinia pestis phospholipase D (Ymt) in the initial aggregation step of biofilm formation in the flea
Published in mBio (12-06-2024)“…Transmission of by fleas depends on the formation of condensed bacterial aggregates embedded within a gel-like matrix that localizes to the proventricular…”
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Upregulation of S100A10 in metastasized breast cancer stem cells
Published in Cancer science (01-12-2020)“…Metastatic progression remains the major cause of death in human breast cancer. Cancer cells with cancer stem cell (CSC) properties drive initiation and growth…”
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SARS-CoV-2 infection of human lung epithelial cells induces TMPRSS-mediated acute fibrin deposition
Published in Nature communications (11-10-2023)“…Severe COVID-associated lung injury is a major confounding factor of hospitalizations and death with no effective treatments. Here, we describe a non-classical…”
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Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF‐1α regulator
Published in Cancer science (01-04-2021)“…We previously reported that ROR1 is a crucial downstream gene for the TTF‐1/NKX2‐1 lineage‐survival oncogene in lung adenocarcinoma, while others have found…”
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Application of fluorinated solvents for cesium ion extraction from aqueous solution by D2EHPA
Published in Separation science and technology (11-12-2020)“…This study focuses on the application of fluorinated solvents, HCFC-225 and HFE347pc-f, for cesium removal and volume reduction of cesium-containing solutions…”
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Effect of pH on the Misincorporation Rate of DNA Polymerase η
Published in Biological & pharmaceutical bulletin (2016)“…The many known eukaryotic DNA polymerases are classified into four families; A, B, X, and Y. Among them, DNA polymerase η, a Y family polymerase, is a low…”
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Enzyme-labeled Antigen Method: Factors Influencing the Deterioration of Antigen-binding Activity of Specific Antibodies during Formalin Fixation and Paraffin Embedding
Published in ACTA HISTOCHEMICA ET CYTOCHEMICA (28-10-2022)“…The enzyme-labeled antigen method is an immunohistochemical technique detecting plasma cells producing specific antibodies in tissue sections. The probe is an…”
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Receptor tyrosine kinase‐like orphan receptor 1, a target of NKX2‐1/TTF‐1 lineage‐survival oncogene, inhibits apoptosis signal‐regulating kinase 1‐mediated pro‐apoptotic signaling in lung adenocarcinoma
Published in Cancer science (01-02-2016)“…We previously identified receptor tyrosine kinase‐like orphan receptor 1 (ROR1) as a transcriptional target of the NKX2‐1/TTF‐1 lineage‐survival oncogene in…”
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Modulation of the sphingolipid rheostat is involved in paclitaxel resistance of the human prostate cancer cell line PC3-PR
Published in Biochemical and biophysical research communications (29-04-2017)“…Taxoids are anti-cancer drugs frequently used to treat solid tumors, but they are sometimes ineffective and tumors may become resistant to their action. Here,…”
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