Search Results - "Suzuki, Minoru"
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Boron neutron capture therapy (BNCT): a unique role in radiotherapy with a view to entering the accelerator-based BNCT era
Published in International journal of clinical oncology (2020)“…Boron neutron capture therapy (BNCT) has a unique property of tumor-cell-selective heavy-particle irradiation. BNCT can form large dose gradients between…”
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Non-isotope enriched phenylboronic acid-decorated dual-functional nano-assembles for an actively targeting BNCT drug
Published in Biomaterials (01-01-2021)“…The feasibility of boron neutron capture therapy (BNCT) greatly depends on the selective accumulation of 10B in tumors. The p-boronophenylalanine-fructose…”
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Boron Neutron Capture Therapy for Malignant Brain Tumors
Published in Neurologia medico-chirurgica (01-01-2016)“…Boron neutron capture therapy (BNCT) is a biochemically targeted radiotherapy based on the nuclear capture and fission reactions that occur when…”
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Cyclic RGD-Functionalized closo-Dodecaborate Albumin Conjugates as Integrin Targeting Boron Carriers for Neutron Capture Therapy
Published in Molecular pharmaceutics (05-10-2020)“…Cyclic RGD (cRGD) peptide-conjugated boronated albumin was developed to direct toward integrin αvβ3, which overexpresses on many cancer cells. A stepwise…”
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Correlation between the expression of LAT1 in cancer cells and the potential efficacy of boron neutron capture therapy
Published in Journal of radiation research (20-01-2023)“…Boron neutron capture therapy (BNCT) is a binary cancer therapy that involves boron administration and neutron irradiation. The nuclear reaction caused by the…”
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Enhancement of Cancer Cell-Killing Effects of Boron Neutron Capture Therapy by Manipulating the Expression of L-Type Amino Acid Transporter 1
Published in Radiation research (06-05-2021)“…In this study, we examined whether the cancer cell-killing effects of boron neutron capture therapy (BNCT) are enhanced by manipulating the expression levels…”
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Current status of boron neutron capture therapy of high grade gliomas and recurrent head and neck cancer
Published in Radiation oncology (London, England) (29-08-2012)“…Boron neutron capture therapy (BNCT) is a biochemically targeted radiotherapy based on the nuclear capture and fission reactions that occur when…”
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Maleimide-functionalized closo-dodecaborate albumin conjugates (MID-AC): Unique ligation at cysteine and lysine residues enables efficient boron delivery to tumor for neutron capture therapy
Published in Journal of controlled release (10-09-2016)“…Maleimide-conjugating closo-dodecaborate sodium form 5c (MID) synthesized by the nucleophilic ring-opening reaction of closo-dodecaborate-1,4-dioxane complex 2…”
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Long-term outcome of cutaneous melanoma patients treated with boron neutron capture therapy (BNCT)
Published in Journal of radiation research (01-11-2020)“…Our aim was to assess the long-term clinical outcome of boron neutron capture therapy (BNCT) using 10B-para-boronophenylalanine (BPA) as the boron delivery…”
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Fructose-functionalized polymers to enhance therapeutic potential of p-boronophenylalanine for neutron capture therapy
Published in Journal of controlled release (10-04-2021)“…In boron neutron capture therapy (BNCT), boron drugs should accumulate selectively within a tumor and be quickly cleared from blood and normal organs. However,…”
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Hybrid Calcium Phosphate-Polymeric Micelles Incorporating Gadolinium Chelates for Imaging-Guided Gadolinium Neutron Capture Tumor Therapy
Published in ACS nano (23-06-2015)“…Gadolinium (Gd) chelates-loaded nanocarriers have high potential for achieving magnetic resonance imaging (MRI)-guided Gd neutron capture therapy (GdNCT) of…”
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Reevaluation of CBE value of BPA for hepatocytes
Published in Applied radiation and isotopes (01-07-2020)“…The compound biological effectiveness (CBE) value of boronophenylalanine (BPA) for hepatocytes was experimentally determined for the purpose of boron neutron…”
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Block copolymer-boron cluster conjugate for effective boron neutron capture therapy of solid tumors
Published in Journal of controlled release (28-05-2017)“…Boron neutron capture therapy is a promising tumor treatment method, though its wide application has been limited due to the poor tumor selectivity and…”
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Conjugation of Phenylboronic Acid Moiety through Multistep Organic Transformations on Nanodiamond Surface for an Anticancer Nanodrug for Boron Neutron Capture Therapy
Published in Bulletin of the Chemical Society of Japan (15-09-2021)“…Detonation nanodiamonds (DNDs) have attracted considerable attention, in particular, in the field of nanomedicine due to their biocompatibility as well as…”
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Identification of ᴅ-amino acid-containing peptides in human serum
Published in PloS one (18-12-2017)“…Biologically uncommon d-aspartate (d-Asp) residues have been shown to accumulate in proteins associated with age-related human disorders, such as cataract and…”
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Potential role of transforming growth factor‐beta 1/Smad signaling in secondary lymphedema after cancer surgery
Published in Cancer science (01-07-2020)“…Secondary lymphedema often develops after cancer surgery, and over 250 million patients suffer from this complication. A major symptom of secondary lymphedema…”
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The mutual relationship between the host immune system and radiotherapy: stimulating the action of immune cells by irradiation
Published in International journal of clinical oncology (01-02-2023)“…The effects of irradiation on tumor tissue and the host immune system are interrelated. The antitumor effect of irradiation is attenuated in the…”
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Polyglycerol Functionalized 10B Enriched Boron Carbide Nanoparticle as an Effective Bimodal Anticancer Nanosensitizer for Boron Neutron Capture and Photothermal Therapies
Published in Small (Weinheim an der Bergstrasse, Germany) (15-09-2022)“…Boron neutron capture therapy (BNCT) is a non‐invasive cancer treatment with little adverse effect utilizing nuclear fission of 10B upon neutron irradiation…”
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A novel method of measuring human lymphatic pumping using indocyanine green fluorescence lymphography
Published in Journal of vascular surgery (01-10-2010)“…Objectives Lymph transportation through the body is partly controlled by the intrinsic pumping of lymphatic vessels. Although an understanding of this process…”
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Improvement of spatial resolution of elemental imaging using laser ablation-ICP-mass spectrometry
Published in Analytical sciences (01-04-2022)“…Laser ablation-ICP-mass spectrometer (LA-ICPMS) now becomes one of the most principal analytical technique for mapping analysis for major to trace elements in…”
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