Search Results - "Suzuki, Kodai"

Tumor-penetrating therapy for β5 integrin-rich pancreas cancer by Hurtado de Mendoza, Tatiana, Mose, Evangeline S., Botta, Gregory P., Braun, Gary B., Kotamraju, Venkata R., French, Randall P., Suzuki, Kodai, Miyamura, Norio, Teesalu, Tambet, Ruoslahti, Erkki, Lowy, Andrew M., Sugahara, Kazuki N.

“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by marked desmoplasia and drug resistance due, in part, to poor drug delivery to extravascular tumor…”
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Brain-Specific Ultrastructure of Capillary Endothelial Glycocalyx and Its Possible Contribution for Blood Brain Barrier by Ando, Yoshiaki, Okada, Hideshi, Takemura, Genzou, Suzuki, Kodai, Takada, Chihiro, Tomita, Hiroyuki, Zaikokuji, Ryogen, Hotta, Yasuaki, Miyazaki, Nagisa, Yano, Hirohisa, Muraki, Isamu, Kuroda, Ayumi, Fukuda, Hirotsugu, Kawasaki, Yuki, Okamoto, Haruka, Kawaguchi, Tomonori, Watanabe, Takatomo, Doi, Tomoaki, Yoshida, Takahiro, Ushikoshi, Hiroaki, Yoshida, Shozo, Ogura, Shinji

“…Endothelial glycocalyx coats healthy vascular endothelium and plays an important role in vascular homeostasis. Although cerebral capillaries are categorized as…”
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Serum syndecan-1 reflects organ dysfunction in critically ill patients by Suzuki, Keiko, Okada, Hideshi, Sumi, Kazuyuki, Tomita, Hiroyuki, Kobayashi, Ryo, Ishihara, Takuma, Kakino, Yoshinori, Suzuki, Kodai, Yoshiyama, Naomasa, Yasuda, Ryu, Kitagawa, Yuichiro, Fukuta, Tetsuya, Miyake, Takahito, Okamoto, Haruka, Doi, Tomoaki, Yoshida, Takahiro, Yoshida, Shozo, Ogura, Shinji, Suzuki, Akio

“…Syndecan-1 (SDC-1) is found in the endothelial glycocalyx and shed into the blood during systemic inflammatory conditions. We investigated organ dysfunction…”
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Ultrastructural Alteration of Pulmonary Capillary Endothelial Glycocalyx During Endotoxemia by Inagawa, Risa, Okada, Hideshi, Takemura, Genzou, Suzuki, Kodai, Takada, Chihiro, Yano, Hirohisa, Ando, Yoshiaki, Usui, Takahiro, Hotta, Yasuaki, Miyazaki, Nagisa, Tsujimoto, Akiko, Zaikokuji, Ryogen, Matsumoto, Atsumu, Kawaguchi, Tomonori, Doi, Tomoaki, Yoshida, Takahiro, Yoshida, Shozo, Kumada, Keisuke, Ushikoshi, Hiroaki, Toyoda, Izumi, Ogura, Shinji

“…The most recent diagnostic criteria for sepsis include organ failure. Microvascular endothelial injury is believed to lead to the multiple organ failure seen…”
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Three-dimensional ultrastructure of capillary endothelial glycocalyx under normal and experimental endotoxemic conditions by Okada, Hideshi, Takemura, Genzou, Suzuki, Kodai, Oda, Kazumasa, Takada, Chihiro, Hotta, Yasuaki, Miyazaki, Nagisa, Tsujimoto, Akiko, Muraki, Isamu, Ando, Yoshiaki, Zaikokuji, Ryogen, Matsumoto, Atsumu, Kitagaki, Hiroki, Tamaoki, Yuto, Usui, Takahiro, Doi, Tomoaki, Yoshida, Takahiro, Yoshida, Shozo, Ushikoshi, Hiroaki, Toyoda, Izumi, Ogura, Shinji

“…Sugar-protein glycocalyx coats healthy endothelium, but its ultrastructure is not well described. Our aim was to determine the three-dimensional ultrastructure…”
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Skin Perfusion Pressure Outperforms Ankle-Brachial Index in Predicting Mortality and Cardiovascular Outcomes in Hemodialysis Patients by Hiratsuka, Maki, Koyama, Katsushi, Kasugai, Takahisa, Suzuki, Kodai, Ide, Atsuki, Miyaguchi, Yuki, Hamano, Takayuki

“…Aims: Skin perfusion pressure (SPP) and ankle-brachial index (ABI) are useful in screening for peripheral arterial disease in patients undergoing hemodialysis…”
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Neutrophil Elastase Damages the Pulmonary Endothelial Glycocalyx in Lipopolysaccharide-Induced Experimental Endotoxemia by Suzuki, Kodai, Okada, Hideshi, Takemura, Genzou, Takada, Chihiro, Kuroda, Ayumi, Yano, Hirohisa, Zaikokuji, Ryogen, Morishita, Kentaro, Tomita, Hiroyuki, Oda, Kazumasa, Matsuo, Saori, Uchida, Akihiro, Fukuta, Tetsuya, Sampei, So, Miyazaki, Nagisa, Kawaguchi, Tomonori, Watanabe, Takatomo, Yoshida, Takahiro, Ushikoshi, Hiroaki, Yoshida, Shozo, Maekawa, Yoichi, Ogura, Shinji

“…Neutrophil elastase (NE) is necessary for effective sterilization of phagocytosed bacterial and fungal pathogens; however, NE increases alveolocapillary…”
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Recombinant thrombomodulin protects against LPS‐induced acute respiratory distress syndrome via preservation of pulmonary endothelial glycocalyx by Suzuki, Kodai, Okada, Hideshi, Takemura, Genzou, Takada, Chihiro, Tomita, Hiroyuki, Yano, Hirohisa, Muraki, Isamu, Zaikokuji, Ryogen, Kuroda, Ayumi, Fukuda, Hirotsugu, Nishio, Ayane, Takashima, Shigeo, Suzuki, Akio, Miyazaki, Nagisa, Fukuta, Tetsuya, Yamada, Noriaki, Watanabe, Takatomo, Doi, Tomoaki, Yoshida, Takahiro, Kumada, Keisuke, Ushikoshi, Hiroaki, Yoshida, Shozo, Ogura, Shinji

“…Background and Purpose Disruption of the endothelial glycocalyx is causally related to microvascular endothelial dysfunction, a characteristic of…”
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Adolescent-onset TAFRO Syndrome with Malignant Nephrosclerosis-like Lesions by Nakayama, Yuki, Mizuno, Hiroki, Sawa, Naoki, Suwabe, Tatsuya, Yamanouchi, Masayuki, Ikuma, Daisuke, Hasegawa, Eiko, Hoshino, Junichi, Sekine, Akinari, Oba, Yuki, Kono, Kei, Kinowaki, Keiichi, Ohashi, Kenichi, Suzuki, Kodai, Sato, Yasuharu, Shimizu, Akira, Yamaguchi, Yutaka, Ubara, Yoshifumi

“…A 16-year-old Japanese girl developed a fever, thrombocytopenia, and renal dysfunction. Treatment was started with steroids, but cervical lymphadenopathy and…”
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Recombinant Antithrombin Attenuates Acute Respiratory Distress Syndrome in Experimental Endotoxemia by Okamoto, Haruka, Muraki, Isamu, Okada, Hideshi, Tomita, Hiroyuki, Suzuki, Kodai, Takada, Chihiro, Wakayama, Yugo, Kuroda, Ayumi, Fukuda, Hirotsugu, Kawasaki, Yuki, Nishio, Ayane, Matsuo, Maho, Tamaoki, Yuto, Inagawa, Risa, Takashima, Shigeo, Taniguchi, Toshiaki, Suzuki, Akio, Suzuki, Keiko, Miyazaki, Nagisa, Kakino, Yoshinori, Yasuda, Ryu, Fukuta, Tetsuya, Kitagawa, Yuichiro, Miyake, Takahito, Doi, Tomoaki, Yoshida, Takahiro, Yoshida, Shozo, Ogura, Shinji

“…Sepsis-induced endothelial acute respiratory distress syndrome is related to microvascular endothelial dysfunction caused by endothelial glycocalyx disruption…”
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Comparative Effectiveness of Emergency Resuscitative Thoracotomy versus Closed Chest Compressions among Patients with Critical Blunt Trauma: A Nationwide Cohort Study in Japan by Suzuki, Kodai, Inoue, Shigeaki, Morita, Seiji, Watanabe, Nobuo, Shintani, Ayumi, Inokuchi, Sadaki, Ogura, Shinji

“…Although emergency resuscitative thoracotomy is performed as a salvage maneuver for critical blunt trauma patients, evidence supporting superior effectiveness…”
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The endothelial glycocalyx—All the same? No, it is not by Suzuki, Kodai, Miura, Tomotaka, Okada, Hideshi

“…The endothelial glycocalyx covers the lumen of blood vessels throughout the body and plays an important role in endothelial homeostasis. Advances in electron…”
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Effects of irrigation system alterations on the trophic position of a threatened top predator in rice‐field ecosystems by Ohba, Shin‐ya, Suzuki, Kodai, Sakai, Yoichiro, Shibata, Jun‐ya, Okuda, Noboru

“…Rice fields serve as alternative habitats for wetland species, and their recent reduction in area due to land conversion is considered one of the main human…”
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Editorial: Vascular Endothelial Glycocalyx in Cardiovascular Disease by Tomita, Hiroyuki, Suzuki, Kodai, Komatsu, Masanobu, Okada, Hideshi

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Neutrophil Elastase Inhibition Ameliorates Endotoxin-induced Myocardial Injury Accompanying Degradation of Cardiac Capillary Glycocalyx by Fukuta, Tetsuya, Okada, Hideshi, Takemura, Genzou, Suzuki, Kodai, Takada, Chihiro, Tomita, Hiroyuki, Suzuki, Akio, Oda, Kazumasa, Uchida, Akihiro, Matsuo, Saori, Fukuda, Hirotsugu, Yano, Hirohisa, Muraki, Isamu, Zaikokuji, Ryogen, Kuroda, Ayumi, Nishio, Ayane, Sampei, So, Miyazaki, Nagisa, Hotta, Yasuaki, Yamada, Noriaki, Watanabe, Takatomo, Morishita, Kentaro, Doi, Tomoaki, Yoshida, Takahiro, Ushikoshi, Hiroaki, Yoshida, Shozo, Maekawa, Yoichi, Ogura, Shinji

“…ABSTRACTMyocardial injury in sepsis may be caused by a burst of several inflammatory mediators, leading to vascular endothelial injuries. However, the…”
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The efficacy and safety of caplacizumab in Japanese patients with immune-mediated thrombotic thrombocytopenic purpura: an open-label phase 2/3 study by Miyakawa, Yoshitaka, Imada, Kazunori, Ichikawa, Satoshi, Uchiyama, Hitoji, Ueda, Yasunori, Yonezawa, Akihito, Fujitani, Shigeki, Ogawa, Yoshiyuki, Matsushita, Tadashi, Asakura, Hidesaku, Nishio, Kenji, Suzuki, Kodai, Hashimoto, Yasuhiro, Murakami, Hidenori, Tahara, Sayaka, Tanaka, Tomoyuki, Matsumoto, Masanori

“…Caplacizumab is an anti-von Willebrand factor humanized single-variable-domain immunoglobulin fragment whose efficacy and safety in immune-mediated thrombotic…”
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Serum syndecan-1 concentration in hospitalized patients with heart failure may predict readmission-free survival by Kitagawa, Yuichiro, Kawamura, Itta, Suzuki, Keiko, Okada, Hideshi, Ishihara, Takuma, Tomita, Hiroyuki, Suzuki, Kodai, Takada, Chihiro, Sampei, So, Kano, Soichiro, Kondo, Kohei, Asano, Hirotaka, Wakayama, Yugo, Kamidani, Ryo, Kawasaki, Yuki, Fukuda, Hirotsugu, Nishio, Ayane, Miyake, Takahito, Fukuta, Tetsuya, Yasuda, Ryu, Oiwa, Hideaki, Kakino, Yoshinori, Miyazaki, Nagisa, Watanabe, Takatomo, Yoshida, Takahiro, Doi, Tomoaki, Suzuki, Akio, Yoshida, Shozo, Matsuo, Hitoshi, Ogura, Shinji

“…Syndecan-1 is found in the endothelial glycocalyx and is released into the bloodstream during stressed conditions, including severe diseases such as acute…”
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Investigation of the relationship between intradialytic hypotension during hemodialysis and serum syndecan-1 concentration by Oiwa, Hideaki, Okada, Hideshi, Suzuki, Keiko, Sumi, Kazuyuki, Yoshida, Shozo, Suzuki, Kodai, Ishihara, Takuma, Kitagaki, Hiroki, Kimura, Kaori, Naito, Yoshihito, Chiba, Naokazu, Kuroda, Ayumi, Uchida, Akihiro, Fukuda, Hirotsugu, Kawasaki, Yuki, Minamiyama, Toru, Nishio, Ayane, Shimada, Takuto, Kamidani, Ryo, Miura, Tomotaka, Tochibora, Ryota, Yamamoto, Saori, Kinomura, Yujiro, Kitagawa, Yuichiro, Fukuta, Tetsuya, Miyake, Takahito, Yoshida, Takahiro, Suzuki, Akio, Tetsuka, Nobuyuki, Tomita, Hiroyuki, Nawa, Takahide, Ogura, Shinji

“…Intradialytic hypotension and arrhythmias are complications of hemodialysis. They are associated with decreased intravascular volume due to reduced…”
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Atypical drug-induced hypersensitivity syndrome with multiple organ failure rescued by combined acute blood purification therapy: a case report by Oiwa, Hideaki, Yoshida, Shozo, Okada, Hideshi, Yasunishi, Masahiro, Kamidani, Ryo, Suzuki, Kodai, Miyake, Takahito, Doi, Tomoaki, Shimohata, Takayoshi, Ogura, Shinji

“…Background Drug-induced hypersensitivity syndrome (DIHS), including Stevens-Johnson syndrome (SJS), is a severe rash that often develops 2–6 weeks after the…”
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Transformation into acute myeloid leukemia with t(8;21)(q22;q22.1); RUNX1::RUNX1T1 from JAK2-mutated essential thrombocythemia: a case report by Asou, Chie, Sakamoto, Tomoyuki, Suzuki, Kodai, Okuda, Itoko, Osaki, Atsushi, Abe, Ryohei, Ito, Yoshihiro, Kakegawa, Emi, Miyakawa, Yoshitaka, Terui, Yasuhito, Nakamura, Yuichi

“…Blast transformation is a rare but well-recognized event in Philadelphia-negative myeloproliferative neoplasms associated with a poor prognosis. Secondary…”
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