Search Results - "Suzu, S"

IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation by Chihara, T, Suzu, S, Hassan, R, Chutiwitoonchai, N, Hiyoshi, M, Motoyoshi, K, Kimura, F, Okada, S

“…Macrophage colony-stimulating factor (M-CSF) regulates the production, survival and function of macrophages through Fms, the receptor tyrosine kinase…”
Get full text

Myeloproliferative leukemia protein activation directly induces fibrocyte differentiation to cause myelofibrosis by Maekawa, T, Osawa, Y, Izumi, T, Nagao, S, Takano, K, Okada, Y, Tachi, N, Teramoto, M, Kawamura, T, Horiuchi, T, Saga, R, Kato, S, Yamamura, T, Watanabe, J, Kobayashi, A, Kobayashi, S, Sato, K, Hashimoto, M, Suzu, S, Kimura, F

“…Myelofibrosis (MF) may be caused by various pathogenic mechanisms such as elevation in circulating cytokine levels, cellular interactions and genetic…”
Get full text

Macropinocytosis and TAK1 mediate anti-inflammatory to pro-inflammatory macrophage differentiation by HIV-1 Nef by Hashimoto, M, Nasser, H, Chihara, T, Suzu, S

“…Macrophages (M Φ ) are functionally classified into two types, anti-inflammatory M2 and pro-inflammatory M1. Importantly, we recently revealed that soluble…”
Get full text

Correction: Myeloproliferative leukemia protein activation directly induces fibrocyte differentiation to cause myelofibrosis by Maekawa, T., Osawa, Y., Izumi, T., Nagao, S., Takano, K., Okada, Y., Tachi, N., Teramoto, M., Kawamura, T., Horiuchi, T., Saga, R., Kato, S., Yamamura, T., Watanabe, J., Kobayashi, A., Kobayashi, S., Sato, K., Hashimoto, M., Suzu, S., Kimura, F.

“…Owing to the insufficient specificity of the anti-myeloproliferative leukemia protein (MPL) antibody in the original version of this Article, Figure 6 and…”
Get full text

Structural analysis of proteoglycan macrophage colony-stimulating factor by KIMURA, F, SUZU, S, NAKAMURA, Y, WAKIMOTO, N, KANATANI, Y, YANAI, N, NAGATA, N, MOTOYOSHI, K

“…Proteoglycan macrophage colony-stimulating factor (PG-M-CSF) was recently reported as a high molecular type of macrophage colony-stimulating factor (M-CSF). We…”
Get full text

M-Sec induced by HTLV-1 mediates an efficient viral transmission by Hiyoshi, Masateru, Takahashi, Naofumi, Eltalkhawy, Youssef M, Noyori, Osamu, Lotfi, Sameh, Panaampon, Jutatip, Okada, Seiji, Tanaka, Yuetsu, Ueno, Takaharu, Fujisawa, Jun-Ichi, Sato, Yuko, Suzuki, Tadaki, Hasegawa, Hideki, Tokunaga, Masahito, Satou, Yorifumi, Yasunaga, Jun-Ichirou, Matsuoka, Masao, Utsunomiya, Atae, Suzu, Shinya

“…Human T-cell leukemia virus type 1 (HTLV-1) infects target cells primarily through cell-to-cell routes. Here, we provide evidence that cellular protein M-Sec…”
Get full text

Biologic activity of proteoglycan macrophage colony-stimulating factor by Suzu, S, Kimura, F, Ota, J, Motoyoshi, K, Itoh, T, Mishima, Y, Yamada, M, Shimamura, S

“…We compared the biologic activities of 85-kDa macrophage-CSF (85-kDa M-CSF), which is fully active, and a proteoglycan M-CSF (PG-M-CSF). Both originate from…”
Get full text

A proteoglycan form of macrophage colony-stimulating factor that binds to bone-derived collagens and can be extracted from bone matrix by Ohtsuki, T, Suzu, S, Hatake, K, Nagata, N, Miura, Y, Motoyoshi, K

“…We previously found that the human osteoblastic cell line MG-63 produces two molecular types of macrophage colony-stimulating factor (M-CSF). One is an 85-kD…”
Get more information

Identification of a high molecular weight macrophage colony-stimulating factor as a glycosaminoglycan-containing species by SUZU, S, OHTUSKI, T, YANAI, N, TAKATSU, Z, KAWASHIMA, T, TAKAKU, F, NAGATA, N, MOTOYOSHI, K

“…Chinese hamster ovary cells transfected with a 4.0-kilobase macrophage colony-stimulating factor (M-CSF) cDNA express two different M-CSF species; one has an…”
Get full text

Biological activity of a proteoglycan form of macrophage colony-stimulating factor and its binding to type V collagen by SUZU, S, OHTSUKI, T, MAKISHIMA, M, YANAI, N, KAWASHIMA, T, NAGATA, N, MOTOYOSHI, K

“…Two different types of macrophage colony-stimulating factors (M-CSF) were found, one with an apparent molecular mass of 85 kDa and the other greater than 200…”
Get full text

Immunohistochemical identification of proteoglycan form of macrophage colony-stimulating factor on bone surface by Ohtsuki, T, Hatake, K, Suzu, S, Saito, K, Motoyoshi, K, Miura, Y

“…Several studies using op/op mice have shown that macrophage colony-stimulating factor (M-CSF) was necessary for osteoclast formation in vivo. Previously we…”
Get full text

Proteoglycan form of macrophage colony-stimulating factor binds low density lipoprotein by Suzu, S, Inaba, T, Yanai, N, Kawashima, T, Yamada, N, Oka, T, Machinami, R, Ohtsuki, T, Kimura, F, Kondo, S

“…We recently isolated a proteoglycan form of macrophage colony-stimulating factor (PG-M-CSF) that carries a chondroitin sulfate glycosaminoglycan chain. Here,…”
Get full text

Characterization of Macrophage Colony-Stimulating Factor in Body Fluids by Immunoblot Analysis by Suzu, Shinya, Yanai, Nobuya, Sato-Somoto, Yuki, Yamada, Muneo, Kawashima, Takuji, Hanamura, Takuji, Nagata, Naokazu, Takaku, Fumimaro, Motoyoshi, Kazuo

“…We characterized the molecular species of human macrophage colony-stimulating factor (hM-CSF) found in serum and urine, using immunoblot analysis after partial…”
Get full text

HIV-1 Nef interferes with M-CSF receptor signaling through Hck activation and inhibits M-CSF bioactivities by Suzu, Shinya, Harada, Hideki, Matsumoto, Takahiro, Okada, Seiji

“…HIV-1 Nef protein is a major determinant of the pathogenicity of the virus. It has been shown that Nef activates Hck, a member of Src family kinase, in…”
Get full text

PS1435 SLAMF7 HIGH CD16 NEGATIVE MONOCYTES INCREASE IN PERIPHERAL BLOOD OF PATIENTS WITH MYELOFIBROSIS IN CORRELATION WITH JAK2V617F MUTATION by Kato, S., Maekawa, T., Ogata, K., Osawa, Y., Nagao, S., Takano, K., Okada, Y., Tachi, N., Teramoto, M., Kawamura, T., Horiuchi, T., Kobayashi, A., Kobayashi, S., Sato, K., Hashimoto, M., Suzu, S., Usuki, K., Morishita, S., Araki, M., Komatsu, N., Kimura, F.

“…Background: Monocyte‐derived fibrocytes are vital in the pathogenesis of primary myelofibrosis (MF) (J Exp Med 2016;213:1723). We established the direct…”
Get full text

Selective expansion and engraftment of human CD16+ NK cells in NOD/SCID mice by Harada, Hideki, Suzu, Shinya, Ito, Takaaki, Okada, Seiji

“…NK cells are large granular lymphocytes that represent a critical component of the innate immunity. Investigations of human NK cell function are largely based…”
Get full text

Molecular cloning of a novel immunoglobulin superfamily gene preferentially expressed by brain and testis by Suzu, Shinya, Hayashi, Yokichi, Harumi, Tatsuo, Nomaguchi, Kouji, Yamada, Muneo, Hayasawa, Hirotoshi, Motoyoshi, Kazuo

“…We have cloned and characterized a novel gene from both human and mouse that encodes a new member of the immunoglobulin superfamily. The gene is preferentially…”
Get full text

Selective Cytotoxic Mechanism of GTP-14564, a Novel Tyrosine Kinase Inhibitor in Leukemia Cells Expressing a Constitutively Active Fms-like Tyrosine Kinase 3 (FLT3) by Murata, Ken, Kumagai, Hidetoshi, Kawashima, Toshiyuki, Tamitsu, Kaori, Irie, Mariko, Nakajima, Hideaki, Suzu, Shinya, Shibuya, Masabumi, Kamihira, Shimeru, Nosaka, Tetsuya, Asano, Shigetaka, Kitamura, Toshio

“…The receptor tyrosine kinase FLT3 is constitutively activated by an internal tandem duplication (ITD) mutation within the juxtamembrane domain in 20–30% of…”
Get full text

p56(dok-2) as a cytokine-inducible inhibitor of cell proliferation and signal transduction by Suzu, S, Tanaka-Douzono, M, Nomaguchi, K, Yamada, M, Hayasawa, H, Kimura, F, Motoyoshi, K

“…p56(dok-2) acts as a multiple docking protein downstream of receptor or non-receptor tyrosine kinases. However, the role of p56(dok-2) in biological functions…”
Get full text

Alteration of the proteoglycan form of macrophage colony-stimulating factor produced by a human stromal line stimulated by tumor necrosis factor-alpha by Ohtsuki, T, Hatake, K, Suzu, S, Harigaya, K, Miura, Y, Motoyoshi, K

“…Immunoblot analysis of macrophage colony-stimulating factor (M-CSF) in KM 102 cell-conditioned medium showed the presence of two M-CSF molecular types, one…”
Get more information