Search Results - "Suzart, Vinicius"
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Mutants of human ACE2 differentially promote SARS-CoV and SARS-CoV-2 spike mediated infection
Published in PLoS pathogens (16-07-2021)“…SARS-CoV and SARS-CoV-2 encode spike proteins that bind human ACE2 on the cell surface to enter target cells during infection. A small fraction of humans…”
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Multiple site place-of-care manufactured anti-CD19 CAR-T cells induce high remission rates in B-cell malignancy patients
Published in Nature communications (10-12-2021)“…Chimeric antigen receptor (CAR) T cells targeting the CD19 antigen are effective in treating adults and children with B-cell malignancies. Place-of-care…”
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Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection
Published in Nature communications (07-08-2018)“…Protective adaptive immunity to Zika virus (ZIKV) has been mainly attributed to cytotoxic CD8 + T cells and neutralizing antibodies, while the participation of…”
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Analyzing human CD4+ T cells activated in response to macrophages infected with Mycobacterium tuberculosis
Published in STAR protocols (15-03-2024)“…M1- and M2-like macrophages infected with Mycobacterium tuberculosis (Mtb) have been found to differ in their capacity to elicit memory CD4+ T cell activation…”
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Trimeric receptor-binding domain of SARS-CoV-2 acts as a potent inhibitor of ACE2 receptor-mediated viral entry
Published in iScience (19-08-2022)“…The COVID-19 pandemic has caused over four million deaths and effective methods to control CoV-2 infection, in addition to vaccines, are needed. The CoV-2…”
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Mycobacterium tuberculosis impairs human memory CD4+ T cell recognition of M2 but not M1-like macrophages
Published in iScience (15-09-2023)“…Direct recognition of Mycobacterium tuberculosis (Mtb)-infected cells is required for protection by CD4+ T cells. While impaired T cell recognition of…”
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Tpl2 Signaling Regulates Dendritic Cell Activation and Responding T Cell Differentiation Following Mycobacterium tuberculosis Infection
Published in The Journal of immunology (1950) (01-05-2021)“…Abstract Mycobacterium tuberculosis (Mtb) utilizes a number of immune evasion mechanisms in order to persist inside of host antigen-presenting cells. Dendritic…”
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