Search Results - "Suyama, Kazuharu"
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Highly Selective and Low-swelling Phosphate-binding Polymer for Hyperphosphatemia Therapy
Published in Chemistry letters (05-09-2012)“…A crosslinked poly(allylamine) was prepared by copolymerization of allylammonium dihydrogen phosphate with N,N′-diallyl-1,3-diaminopropane bis(dihydrogen…”
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Discovery and structure–activity relationship of 2,6-disubstituted pyrazines, potent and selective inhibitors of protein kinase CK2
Published in Bioorganic & medicinal chemistry letters (01-07-2012)“…We report the discovery and structure–activity relationship of 2,6-disubstituted pyrazines, which are potent and selective CK2 inhibitors. Lead compound 1 was…”
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Effect of fatty acids on the phosphate binding of TRK-390, a novel, highly selective phosphate-binding polymer
Published in European journal of pharmacology (15-08-2013)“…Phosphate binders are used for the treatment of hyperphosphatemia in hemodialysis patients with chronic kidney disease. Sevelamer, a phosphate-binding polymer,…”
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Design and synthesis of novel p38α MAP kinase inhibitors: Discovery of pyrazole-benzyl ureas bearing 2-molpholinopyrimidine moiety
Published in Bioorganic & medicinal chemistry letters (01-08-2012)“…The discovery that pyrazole-benzyl urea derivatives bearing a 2-molpholinopyrimidine moiety are novel p38α inhibitors is described. A comparative view of the…”
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