Search Results - "Suwanborirux, Khanit"

5-O-Acetyl-Renieramycin T from Blue Sponge Xestospongia sp. Induces Lung Cancer Stem Cell Apoptosis by Chantarawong, Wipa, Chamni, Supakarn, Suwanborirux, Khanit, Saito, Naoki, Chanvorachote, Pithi

“…Lung cancer is one of the most significant cancers as it accounts for almost 1 in 5 cancer deaths worldwide, with an increasing incident rate. Management of…”
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Chemistry of Renieramycins. Part 19: Semi-Syntheses of 22- O -Amino Ester and Hydroquinone 5- O -Amino Ester Derivatives of Renieramycin M and Their Cytotoxicity against Non-Small-Cell Lung Cancer Cell Lines by Chamni, Supakarn, Sirimangkalakitti, Natchanun, Chanvorachote, Pithi, Suwanborirux, Khanit, Saito, Naoki

“…Two new series of synthetic renieramycins including 22- -amino ester and hydroquinone 5- -amino ester derivatives of renieramycin M were semi-synthesized and…”
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Renieramycin M Attenuates Cancer Stem Cell-like Phenotypes in H460 Lung Cancer Cells by Sirimangkalakitti, Natchanun, Chamni, Supakarn, Suwanborirux, Khanit, Chanvorachote, Pithi

“…Cancer stem cells (CSCs) are a subpopulation of cancer cells that possess self-renewal and differentiation capacities. CSCs contribute to drug-resistance,…”
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Renieramycin T Induces Lung Cancer Cell Apoptosis by Targeting Mcl-1 Degradation: A New Insight in the Mechanism of Action by Petsri, Korrakod, Chamni, Supakarn, Suwanborirux, Khanit, Saito, Naoki, Chanvorachote, Pithi

“…Among malignancies, lung cancer is the major cause of cancer death. Despite the advance in lung cancer therapy, the five-year survival rate is extremely…”
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Semisynthesis of 5-O-ester derivatives of renieramycin T and their cytotoxicity against non-small-cell lung cancer cell lines by Buaban, Koonchira, Innets, Bhurichaya, Petsri, Korrakod, Sinsook, Suwimon, Chanvorachote, Pithi, Chansriniyom, Chaisak, Suwanborirux, Khanit, Yokoya, Masashi, Saito, Naoki, Chamni, Supakarn

“…The semisynthesis of 5- O -ester derivatives of renieramycin T was accomplished through the photoredox reaction of renieramycin M ( 1 ), a…”
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22-O-(N-Boc-l-glycine) ester of renieramycin M inhibits migratory activity and suppresses epithelial–mesenchymal transition in human lung cancer cells by Oo, Yamin, Nealiga, Justin Quiel Lasam, Suwanborirux, Khanit, Chamni, Supakarn, Ecoy, Gea Abigail Uy, Pongrakhananon, Varisa, Chanvorachote, Pithi, Chaotham, Chatchai

“…The incidence of metastasis stage crucially contributes to high recurrence and mortality rate in lung cancer patients. Unfortunately, no available treatment…”
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Jorunnamycin A Suppresses Stem-Like Phenotypes and Sensitizes Cisplatin-Induced Apoptosis in Cancer Stem-Like Cell-Enriched Spheroids of Human Lung Cancer Cells by Sumkhemthong, Somruethai, Chamni, Supakarn, Ecoy, Gea U., Taweecheep, Pornchanok, Suwanborirux, Khanit, Prompetchara, Eakachai, Chanvorachote, Pithi, Chaotham, Chatchai

“…It has been recognized that cancer stem-like cells (CSCs) in tumor tissue crucially contribute to therapeutic failure, resulting in a high mortality rate in…”
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Synergistic Cytotoxicity of Renieramycin M and Doxorubicin in MCF-7 Breast Cancer Cells by Tun, Jortan O, Salvador-Reyes, Lilibeth A, Velarde, Michael C, Saito, Naoki, Suwanborirux, Khanit, Concepcion, Gisela P

“…Renieramycin M (RM) is a KCN-stabilized tetrahydroisoquinoline purified from the blue sponge sp., with nanomolar IC s against several cancer cell lines. Our…”
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Micromonospora fluostatini sp. nov., isolated from marine sediment by Phongsopitanun, Wongsakorn, Kudo, Takuji, Mori, Mihoko, Shiomi, Kazuro, Pittayakhajonwut, Pattama, Suwanborirux, Khanit, Tanasupawat, Somboon

“…The novel actinomycete strain PWB-003T, which produced fluostatins B and C antibiotics, was isolated from nearshore sediment collected from Panwa Cape, Phuket…”
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Light-Mediated Transformation of Renieramycins and Semisynthesis of 4'-Pyridinecarbonyl-Substituted Renieramycin-Type Derivatives as Potential Cytotoxic Agents against Non-Small-Cell Lung Cancer Cells by Sinsook, Suwimon, Buaban, Koonchira, Iksen, Iksen, Petsri, Korrakod, Innets, Bhurichaya, Chansriniyom, Chaisak, Suwanborirux, Khanit, Yokoya, Masashi, Saito, Naoki, Pongrakhananon, Varisa, Chanvorachote, Pithi, Chamni, Supakarn

“…The semisynthesis of renieramycin-type derivatives was achieved under mild and facile conditions by attaching a 1,3-dioxole-bridged phenolic moiety onto ring A…”
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Semisynthesis and biological evaluation of prenylated resveratrol derivatives as multi-targeted agents for Alzheimer’s disease by Puksasook, Thanchanok, Kimura, Shinya, Tadtong, Sarin, Jiaranaikulwanitch, Jutamas, Pratuangdejkul, Jaturong, Kitphati, Worawan, Suwanborirux, Khanit, Saito, Naoki, Nukoolkarn, Veena

“…A series of prenylated resveratrol derivatives were designed, semisynthesized and biologically evaluated for inhibition of β-secretase (BACE1) and amyloid-β…”
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5- O -( N -Boc-l-Alanine)-Renieramycin T Induces Cancer Stem Cell Apoptosis via Targeting Akt Signaling by Suksamai, Darinthip, Racha, Satapat, Sriratanasak, Nicharat, Chaotham, Chatchai, Aphicho, Kanokpol, Lin, Aye Chan Khine, Chansriniyom, Chaisak, Suwanborirux, Khanit, Chamni, Supakarn, Chanvorachote, Pithi

“…Cancer stem cells (CSCs) drive aggressiveness and metastasis by utilizing stem cell-related signals. In this study, 5- -( -Boc-l-alanine)-renieramycin T…”
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Variation of Carbon–Nitrogen Contents and Allelopathic Disruption of Renieramycin M–Producing Sponge Xestospongia sp. in the Gulf of Thailand by Darumas, Udomsak, Salem, Gad Elsayed Mohamed, Suwanborirux, Khanit, Viyakarn, Voranop, Chavanich, Suchana

“…Allelopathy is commonly found in marine sponges. However, information on allelopathic activities of sponge extracts is limited. In this study, variations of…”
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Synthesis and Absolute Configuration of Acanthodendrilline, a New Cytotoxic Bromotyrosine Alkaloid from the Thai Marine Sponge Acanthodendrilla sp by Sirimangkalakitti, Nachanun, Yokoya, Masashi, Chamni, Supakarn, Chanvorachote, Pithi, Plubrukrn, Anuchit, Saito, Naoki, Suwanborirux, Khanit

“…Acanthodendrilline (1), a new bromotyrosine alkaloid, was isolated from the Thai marine sponge Acanthodendrilla sp. The structure of 1 was fully characterized…”
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2D-QSAR and CoMFA Models for Antitubercular Activity of Scalarane-Type Sesterterpenes by Thengyai, Suriyan, Guo, Yuewei, Suwanborirux, Khanit, Berner, Heinz, Spreitzer, Helmut, Wolschann, Peter, Hannongbua, Supa, Plubrukarn, Anuchit

“…A series of scalarane sesterterpenes were prepared using heteronemin (1) as a primary precursor. Combined with the scalarane derivatives obtained from natural…”
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Azole-synergistic anti-candidal activity of altenusin, a biphenyl metabolite of the endophytic fungus Alternaria alternata isolated from Terminalia chebula Retz by Phaopongthai, Jatuporn, Wiyakrutta, Suthep, Meksuriyen, Duangdeun, Sriubolmas, Nongluksna, Suwanborirux, Khanit

“…In this study, a tropical endophytic fungus, Alternaria alternata Tche-153 was isolated from a Thai medicinal plant Terminalia chebula Rezt. The ethyl acetate…”
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Chemistry of Ecteinascidins. Part 5: An Additional Proof of Cytotoxicity Evaluation of Ecteinascidin 770 Derivatives by Toyoshima, Ryoko, Mori, Nanae, Suzuki, Toshihiro, Lowtangkitcharoen, Witaya, Suwanborirux, Khanit, Saito, Naoki

“…Eleven 2′-N-acyl derivatives (5a–k) were prepared from ecteinascidin 770 (Et 770: 1b) via known 18,6′-O-bisallyl-protected compound (3) in three steps. Their…”
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Replacement of a Quinone by a 5‑O‑Acetylhydroquinone Abolishes the Accidental Necrosis Inducing Effect while Preserving the Apoptosis-Inducing Effect of Renieramycin M on Lung Cancer Cells by Cheun-Arom, Thaniwan, Chanvorachote, Pithi, Sirimangkalakitti, Natchanun, Chuanasa, Taksina, Saito, Naoki, Abe, Ikuro, Suwanborirux, Khanit

“…Renieramycin M (1), a bistetrahydroisoquinolinequinone alkaloid isolated from the marine sponge Xestospongia sp., has been reported to possess promising…”
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Acetylcholinesterase-inhibiting activity of pyrrole derivatives from a novel marine gliding bacterium, Rapidithrix thailandica by Sangnoi, Yutthapong, Sakulkeo, Oraphan, Yuenyongsawad, Supreeya, Kanjana-opas, Akkharawit, Ingkaninan, Kornkanok, Plubrukarn, Anuchit, Suwanborirux, Khanit

“…Acetylcholinesterase-inhibiting activity of marinoquinoline A (1), a new pyrroloquinoline from a novel species of a marine gliding bacterium Rapidithrix…”
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Chemistry of Ecteinascidins. Part 4: Preparation of 2′-N-Acyl Ecteinascidin 770 Derivatives with Improved Cytotoxicity Profiles by Tsujimoto, Mitsuhiro, Lowtangkitcharoen, Witaya, Mori, Nanae, Pangkruang, Waree, Putongking, Ploenthip, Suwanborirux, Khanit, Saito, Naoki

“…We report herein eleven 2′-N-acyl derivatives that were prepared from ecteinascidin 770 (Et 770: 1b) via 18,6′-O-bisallyl protected compound (4) in excellent…”
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