Search Results - "Suuronen, Erik J."

Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention by Khatoon, Zohra, McTiernan, Christopher D., Suuronen, Erik J., Mah, Thien-Fah, Alarcon, Emilio I.

“…In living organisms, biofilms are defined as complex communities of bacteria residing within an exopolysaccharide matrix that adheres to a surface. In the…”
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Injectable human recombinant collagen matrices limit adverse remodeling and improve cardiac function after myocardial infarction by McLaughlin, Sarah, McNeill, Brian, Podrebarac, James, Hosoyama, Katsuhiro, Sedlakova, Veronika, Cron, Gregory, Smyth, David, Seymour, Richard, Goel, Keshav, Liang, Wenbin, Rayner, Katey J., Ruel, Marc, Suuronen, Erik J., Alarcon, Emilio I.

“…Despite the success of current therapies for acute myocardial infarction (MI), many patients still develop adverse cardiac remodeling and heart failure. With…”
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Stable corneal regeneration four years after implantation of a cell-free recombinant human collagen scaffold by Fagerholm, Per, Lagali, Neil S, Ong, Jeb A, Merrett, Kimberley, Jackson, W. Bruce, Polarek, James W, Suuronen, Erik J, Liu, Yuwen, Brunette, Isabelle, Griffith, May

“…Abstract We developed cell-free implants, comprising carbodiimide crosslinked recombinant human collagen (RHC), to enable corneal regeneration by endogenous…”
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Mimicking biofilm formation and development: Recent progress in in vitro and in vivo biofilm models by Guzmán-Soto, Irene, McTiernan, Christopher, Gonzalez-Gomez, Mayte, Ross, Alex, Gupta, Keshav, Suuronen, Erik J., Mah, Thien-Fah, Griffith, May, Alarcon, Emilio I.

“…Biofilm formation in living organisms is associated to tissue and implant infections, and it has also been linked to the contribution of antibiotic resistance…”
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The Progression of Regenerative Medicine and its Impact on Therapy Translation by Jacques, Erik, Suuronen, Erik J.

“…Despite regenerative medicine (RM) being one of the hottest topics in biotechnology for the past 3 decades, it is generally acknowledged that the field’s…”
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Methylglyoxal-Induced Endothelial Cell Loss and Inflammation Contribute to the Development of Diabetic Cardiomyopathy by Vulesevic, Branka, McNeill, Brian, Giacco, Ferdinando, Maeda, Kay, Blackburn, Nick J R, Brownlee, Michael, Milne, Ross W, Suuronen, Erik J

“…The mechanisms for the development of diabetic cardiomyopathy remain largely unknown. Methylglyoxal (MG) can accumulate and promote inflammation and vascular…”
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A low cost and open access system for rapid synthesis of large volumes of gold and silver nanoparticles by Ross, Alex, Muñoz, Marcelo, Rotstein, Benjamin H., Suuronen, Erik J., Alarcon, Emilio I.

“…Rapid synthesis of nanomaterials in scalable quantities is critical for accelerating the discovery and commercial translation of nanoscale-based technologies…”
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Exploiting extracellular matrix-stem cell interactions: A review of natural materials for therapeutic muscle regeneration by Kuraitis, Drew, Giordano, Céline, Ruel, Marc, Musarò, Antonio, Suuronen, Erik J

“…Abstract Myopathies of skeletal muscle are prevalent diseases worldwide. To address this, regenerative therapies are being developed to restore perfusion to…”
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Trichostatin A Enhances Vascular Repair by Injected Human Endothelial Progenitors through Increasing the Expression of TAL1-Dependent Genes by Palii, Carmen G., Vulesevic, Branka, Fraineau, Sylvain, Pranckeviciene, Erinija, Griffith, Alexander J., Chu, Alphonse, Faralli, Hervé, Li, Yuhua, McNeill, Brian, Sun, Jie, Perkins, Theodore J., Dilworth, F. Jeffrey, Perez-Iratxeta, Carol, Suuronen, Erik J., Allan, David S., Brand, Marjorie

“…A major goal of cell therapy for vascular diseases is to promote revascularization through the injection of endothelial stem/progenitor cells. The gene…”
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Publisher's Note: A necrotic stimulus is required to maximize matrix-mediated myogenesis in mice by Kuraitis, Drew, Grazia Berardinelli, Maria, Suuronen, Erik J, Musarò, Antonio

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Development of in situ bioprinting: A mini review by MacAdam, Aidan, Chaudry, Emaan, McTiernan, Christopher D, Cortes, David, Suuronen, Erik J, Alarcon, Emilio I

“…Bioprinting has rapidly progressed over the past decade. One branch of bioprinting known as bioprinting has benefitted considerably from innovations in…”
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BEaTS-α an open access 3D printed device for in vitro electromechanical stimulation of human induced pluripotent stem cells by Cortes, David, McTiernan, Christopher D., Ruel, Marc, Franco, Walfre, Chu, Cencen, Liang, Wenbin, Suuronen, Erik J., Alarcon, Emilio I.

“…3D printing was used to develop an open access device capable of simultaneous electrical and mechanical stimulation of human induced pluripotent stem cells in…”
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Safety and efficacy of composite collagen-silver nanoparticle hydrogels as tissue engineering scaffolds by Alarcon, Emilio I, Udekwu, Klas I, Noel, Christopher W, Gagnon, Luke B-P, Taylor, Patrick K, Vulesevic, Branka, Simpson, Madeline J, Gkotzis, Spyridon, Islam, M Mirazul, Lee, Chyan-Jang, Richter-Dahlfors, Agneta, Mah, Thien-Fah, Suuronen, Erik J, Scaiano, Juan C, Griffith, May

“…The increasing number of multidrug resistant bacteria has revitalized interest in seeking alternative sources for controlling bacterial infection. Silver…”
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Evaluation of a collagen-chitosan hydrogel for potential use as a pro-angiogenic site for islet transplantation by McBane, Joanne E, Vulesevic, Branka, Padavan, Donna T, McEwan, Kimberly A, Korbutt, Gregory S, Suuronen, Erik J

“…Islet transplantation to treat type 1 diabetes (T1D) has shown varied long-term success, due in part to insufficient blood supply to maintain the islets. In…”
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Manufacturing and validation of small-diameter vascular grafts: A mini review by Hernandez-Sanchez, Deyanira, Comtois-Bona, Maxime, Muñoz, Marcelo, Ruel, Marc, Suuronen, Erik J., Alarcon, Emilio I.

“…The field of small-diameter vascular grafts remains a challenge for biomaterials scientists. While decades of research have brought us much closer to…”
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Glyoxalase-1 overexpression in bone marrow cells reverses defective neovascularization in STZ-induced diabetic mice by Vulesevic, Branka, McNeill, Brian, Geoffrion, Michele, Kuraitis, Drew, McBane, Joanne E, Lochhead, Marina, Vanderhyden, Barbara C, Korbutt, Gregory S, Milne, Ross W, Suuronen, Erik J

“…Methylglyoxal (MG) accumulates in diabetes and impairs neovascularization. This study assessed whether overexpressing the MG-metabolizing enzyme glyoxalase-1…”
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Click hydrogels, microgels and nanogels: Emerging platforms for drug delivery and tissue engineering by Jiang, Yanjiao, Chen, Jing, Deng, Chao, Suuronen, Erik J, Zhong, Zhiyuan

“…Abstract Hydrogels, microgels and nanogels have emerged as versatile and viable platforms for sustained protein release, targeted drug delivery, and tissue…”
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Reducing methylglyoxal as a therapeutic target for diabetic heart disease by Vulesevic, Branka, Milne, Ross W, Suuronen, Erik J

“…Diabetes is a well-known risk factor for the development of cardiovascular diseases. Diabetes affects cardiac tissue through several different, yet…”
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How Biomaterials Can Influence Various Cell Types in the Repair and Regeneration of the Heart after Myocardial Infarction by Lister, Zachary, Rayner, Katey J, Suuronen, Erik J

“…The healthy heart comprises many different cell types that work together to preserve optimal function. However, in a diseased heart the function of one or more…”
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Injectable Small Intestine Submucosal Extracellular Matrix in an Acute Myocardial Infarction Model by Toeg, Hadi Daood, MD, MS, Tiwari-Pandey, Rashmi, PhD, Seymour, Richard, BS, Ahmadi, Ali, MD, Crowe, Suzanne, BS, Vulesevic, Branka, MS, Suuronen, Erik J., PhD, Ruel, Marc, MD, MPH

“…Background The mechanisms involved in myocardial regeneration and cardiac remodeling were examined by injecting porcine-derived small intestine submucosal…”
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