Search Results - "Sutton, Troy C."

The Pandemic Threat of Emerging H5 and H7 Avian Influenza Viruses by Sutton, Troy C

“…The 1918 H1N1 Spanish Influenza pandemic was the most severe pandemic in modern history. Unlike more recent pandemics, most of the 1918 H1N1 virus' genome was…”
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Risk assessment of a highly pathogenic H5N1 influenza virus from mink by Restori, Katherine H., Septer, Kayla M., Field, Cassandra J., Patel, Devanshi R., VanInsberghe, David, Raghunathan, Vedhika, Lowen, Anice C., Sutton, Troy C.

“…Outbreaks of highly pathogenic H5N1 clade 2.3.4.4b viruses in farmed mink and seals combined with isolated human infections suggest these viruses pose a…”
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Novel Reassortant Human-Like H3N2 and H3N1 Influenza A Viruses Detected in Pigs Are Virulent and Antigenically Distinct from Swine Viruses Endemic to the United States by Rajão, Daniela S, Gauger, Phillip C, Anderson, Tavis K, Lewis, Nicola S, Abente, Eugenio J, Killian, Mary Lea, Perez, Daniel R, Sutton, Troy C, Zhang, Jianqiang, Vincent, Amy L

“…Human-like swine H3 influenza A viruses (IAV) were detected by the USDA surveillance system. We characterized two novel swine human-like H3N2 and H3N1 viruses…”
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Sequential Transmission of Influenza Viruses in Ferrets Does Not Enhance Infectivity and Does Not Predict Transmissibility in Humans by Sutton, Troy C, Lamirande, Elaine W, Patel, Devanshi R, Johnson, Katherine E E, Czako, Rita, Ghedin, Elodie, Lee, Raphael T C, Maurer-Stroh, Sebastian, Subbarao, Kanta

“…Airborne transmission in ferrets is a key component of pandemic risk assessment. However, some emerging avian influenza viruses transmit between ferrets but do…”
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Vitamin D and the Ability to Produce 1,25(OH)2D Are Critical for Protection from Viral Infection of the Lungs by Arora, Juhi, Patel, Devanshi R., Nicol, McKayla J., Field, Cassandra J., Restori, Katherine H., Wang, Jinpeng, Froelich, Nicole E., Katkere, Bhuvana, Terwilliger, Josey A., Weaver, Veronika, Luley, Erin, Kelly, Kathleen, Kirimanjeswara, Girish S., Sutton, Troy C., Cantorna, Margherita T.

“…Vitamin D supplementation is linked to improved outcomes from respiratory virus infection, and the COVID-19 pandemic renewed interest in understanding the…”
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Alternative Reassortment Events Leading to Transmissible H9N1 Influenza Viruses in the Ferret Model by Kimble, J Brian, Angel, Matthew, Wan, Hongquan, Sutton, Troy C, Finch, Courtney, Perez, Daniel R

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Intranasal SARS-CoV-2 RBD decorated nanoparticle vaccine enhances viral clearance in the Syrian hamster model by Patel, Devanshi R, Minns, Allen M, Sim, Derek G, Field, Cassandra J, Kerr, Abigail E, Heinly, Talia A, Luley, Erin H, Rossi, Randall M, Bator, Carol M, Moustafa, Ibrahim M, Norton, Elizabeth B, Hafenstein, Susan L, Lindner, Scott E, Sutton, Troy C

“…Multiple vaccines have been developed and licensed for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). While these vaccines reduce disease…”
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Receptor Characterization and Susceptibility of Cotton Rats to Avian and 2009 Pandemic Influenza Virus Strains by Blanco, Jorge C G, Pletneva, Lioubov M, Wan, Hongquan, Araya, Yonas, Angel, Matthew, Oue, Raymonde O, Sutton, Troy C, Perez, Daniel R

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Changes in the Hemagglutinin and Internal Gene Segments Were Needed for Human Seasonal H3 Influenza A Virus to Efficiently Infect and Replicate in Swine by Rajao, Daniela S, Abente, Eugenio J, Powell, Joshua D, Bolton, Marcus J, Gauger, Phillip C, Arruda, Bailey, Anderson, Tavis K, Sutton, Troy C, Perez, Daniel R, Vincent Baker, Amy L

“…The current diversity of influenza A viruses (IAV) circulating in swine is largely a consequence of human-to-swine transmission events and consequent evolution…”
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Aerosolized Hydrogen Peroxide Decontamination of N95 Respirators, with Fit-Testing and Viral Inactivation, Demonstrates Feasibility for Reuse during the COVID-19 Pandemic by Derr, T Hans, James, Melissa A, Kuny, Chad V, Patel, Devanshi R, Kandel, Prem P, Field, Cassandra, Beckman, Matthew D, Hockett, Kevin L, Bates, Mark A, Sutton, Troy C, Szpara, Moriah L

“…In response to the demand for N95 respirators by health care workers during the COVID-19 pandemic, we evaluated decontamination of N95 respirators using an…”
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The effect of grafted methoxypoly(ethylene glycol) chain length on the inhibition of respiratory syncytial virus (RSV) infection and proliferation by Sutton, Troy C, Scott, Mark D

“…Abstract Respiratory syncytial virus (RSV) is a significant cause of morbidity in humans. To date, no effective treatments exist and current prophylactic…”
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Evaluation of the Biological Properties and Cross-Reactive Antibody Response to H10 Influenza Viruses in Ferrets by Sutton, Troy C, Lamirande, Elaine W, Czako, Rita, Subbarao, Kanta

“…The recent outbreak of avian origin H10N7 influenza among seals in northern Europe and two fatal human infections with an avian H10N8 virus in China have…”
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Transmission and Protection against Reinfection in the Ferret Model with the SARS-CoV-2 USA-WA1/2020 Reference Isolate by Patel, Devanshi R, Field, Cassandra J, Septer, Kayla M, Sim, Derek G, Jones, Matthew J, Heinly, Talia A, Vanderford, Thomas H, McGraw, Elizabeth A, Sutton, Troy C

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has initiated a global pandemic, and several vaccines have now received emergency use…”
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In Vitro Neutralization Is Not Predictive of Prophylactic Efficacy of Broadly Neutralizing Monoclonal Antibodies CR6261 and CR9114 against Lethal H2 Influenza Virus Challenge in Mice by Sutton, Troy C, Lamirande, Elaine W, Bock, Kevin W, Moore, Ian N, Koudstaal, Wouter, Rehman, Muniza, Weverling, Gerrit Jan, Goudsmit, Jaap, Subbarao, Kanta

“…Influenza viruses of the H1N1, H2N2, and H3N2 subtypes have caused previous pandemics. H2 influenza viruses represent a pandemic threat due to continued…”
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Improved hatchability and efficient protection after in ovo vaccination with live-attenuated H7N2 and H9N2 avian influenza viruses by Cai, Yibin, Song, Haichen, Ye, Jianqiang, Shao, Hongxia, Padmanabhan, Rangarajan, Sutton, Troy C, Perez, Daniel R

“…Mass in ovo vaccination with live attenuated viruses is widely used in the poultry industry to protect against various infectious diseases. The worldwide…”
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Development of animal models against emerging coronaviruses: From SARS to MERS coronavirus by Sutton, Troy C, Subbarao, Kanta

“…Abstract Two novel coronaviruses have emerged to cause severe disease in humans. While bats may be the primary reservoir for both viruses, SARS coronavirus…”
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Airborne transmission of highly pathogenic H7N1 influenza virus in ferrets by Sutton, Troy C, Finch, Courtney, Shao, Hongxia, Angel, Matthew, Chen, Hongjun, Capua, Ilaria, Cattoli, Giovanni, Monne, Isabella, Perez, Daniel R

“…Avian H7 influenza viruses are recognized as potential pandemic viruses, as personnel often become infected during poultry outbreaks. H7 infections in humans…”
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Transmission of Human Influenza A Virus in Pigs Selects for Adaptive Mutations on the HA Gene by Mo, Jong-Suk, Abente, Eugenio J, Cardenas Perez, Matias, Sutton, Troy C, Cowan, Brianna, Ferreri, Lucas M, Geiger, Ginger, Gauger, Phillip C, Perez, Daniel R, Vincent Baker, Amy L, Rajao, Daniela S

“…Influenza A viruses (FLUAV) cause respiratory diseases in many host species, including humans and pigs. The spillover of FLUAV between swine and humans has…”
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Genome rearrangement of influenza virus for anti-viral drug screening by Sutton, Troy C., Obadan, Adebimpe, Lavigne, Johanna, Chen, Hongjun, Li, Weizhong, Perez, Daniel R.

“…•The viral genome of A/California/04/2009 (H1N1) can be rearranged to express GFP or Gaussia luciferase (GLuc).•Amantadine sensitive and resistant GLuc…”
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Robustness of the Ferret Model for Influenza Risk Assessment Studies: a Cross-Laboratory Exercise by Belser, Jessica A., Lau, Eric H. Y., Barclay, Wendy, Barr, Ian G., Chen, Hualan, Fouchier, Ron A. M., Hatta, Masato, Herfst, Sander, Kawaoka, Yoshihiro, Lakdawala, Seema S., Lee, Leo Yi Yang, Neumann, Gabriele, Peiris, Malik, Perez, Daniel R., Russell, Charles, Subbarao, Kanta, Sutton, Troy C., Webby, Richard J., Yang, Huanliang, Yen, Hui-Ling

“…Past pandemic influenza viruses with sustained human-to-human transmissibility have emerged from animal influenza viruses. Employment of experimental models to…”
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