Search Results - "Suthers, Graeme K."

Immunohistochemical testing of conventional adenomas for loss of expression of mismatch repair proteins in Lynch syndrome mutation carriers: a case series from the Australasian site of the colon cancer family registry by Walsh, Michael D, Buchanan, Daniel D, Pearson, Sally-Ann, Clendenning, Mark, Jenkins, Mark A, Win, Aung Ko, Walters, Rhiannon J, Spring, Kevin J, Nagler, Belinda, Pavluk, Erika, Arnold, Sven T, Goldblatt, Jack, George, Jill, Suthers, Graeme K, Phillips, Kerry, Hopper, John L, Jass, Jeremy R, Baron, John A, Ahnen, Dennis J, Thibodeau, Stephen N, Lindor, Noralane, Parry, Susan, Walker, Neal I, Rosty, Christophe, Young, Joanne P

“…Debate continues as to the usefulness of assessing adenomas for loss of mismatch repair protein expression to identify individuals with suspected Lynch…”
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Comparing the performance of gene expression assays in breast cancer by Suthers, Graeme K.

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Novel germ line DDX41 mutations define families with a lower age of MDS/AML onset and lymphoid malignancies by Lewinsohn, Maya, Brown, Anna L., Weinel, Luke M., Phung, Connie, Rafidi, George, Lee, Ming K., Schreiber, Andreas W., Feng, Jinghua, Babic, Milena, Chong, Chan-Eng, Lee, Young, Yong, Agnes, Suthers, Graeme K., Poplawski, Nicola, Altree, Meryl, Phillips, Kerry, Jaensch, Louise, Fine, Miriam, D'Andrea, Richard J., Lewis, Ian D., Medeiros, Bruno C., Pollyea, Daniel A., King, Mary-Claire, Walsh, Tom, Keel, Siobán, Shimamura, Akiko, Godley, Lucy A., Hahn, Christopher N., Churpek, Jane E., Scott, Hamish S.

“…Recently our group and others have identified DDX41 mutations both as germ line and acquired somatic mutations in families with multiple cases of late onset…”
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Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia by Scott, Hamish S, Hahn, Christopher N, Chong, Chan-Eng, Carmichael, Catherine L, Wilkins, Ella J, Brautigan, Peter J, Li, Xiao-Chun, Babic, Milena, Lin, Ming, Carmagnac, Amandine, Lee, Young K, Kok, Chung H, Gagliardi, Lucia, Friend, Kathryn L, Ekert, Paul G, Butcher, Carolyn M, Brown, Anna L, Lewis, Ian D, To, L Bik, Timms, Andrew E, Storek, Jan, Moore, Sarah, Altree, Meryl, Escher, Robert, Bardy, Peter G, Suthers, Graeme K, D'Andrea, Richard J, Horwitz, Marshall S

“…We report the discovery of GATA2 as a new myelodysplastic syndrome (MDS)-acute myeloid leukemia (AML) predisposition gene. We found the same, previously…”
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Rising incidence of early-onset colorectal cancer in Australia over two decades: Report and review by Young, Joanne P, Win, Aung Ko, Rosty, Christophe, Flight, Ingrid, Roder, David, Young, Graeme P, Frank, Oliver, Suthers, Graeme K, Hewett, Peter J, Ruszkiewicz, Andrew, Hauben, Ehud, Adelstein, Barbara-Ann, Parry, Susan, Townsend, Amanda, Hardingham, Jennifer E, Price, Timothy J

“…The average age at diagnosis for colorectal cancer (CRC) in Australia is 69, and the age‐specific incidence rises rapidly after age 50 years. The incidence has…”
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Letter to the editor: reply to Bousman et al by Suthers, Graeme K, Polasek, Tom M

“…Letter regarding: Bousman CA, Arandjelovic K, Mancuso SG, Eyre HA, Dunlop BW. Pharmacogenetic tests and depressive symptom remission: a meta-analysis of…”
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Diagnostic performance and costs of contingent screening models for trisomy 21 incorporating non‐invasive prenatal testing by Maxwell, Susannah, O'Leary, Peter, Dickinson, Jan E., Suthers, Graeme K.

“…Background Contingent screening for trisomy 21 using non‐invasive prenatal testing has the potential to reduce invasive diagnostic testing and increase the…”
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Congenital hypertrophy of the retinal pigment epithelium (CHRPE) in familial colorectal cancer by Chen, Celia S, Phillips, Kerry D, Grist, Scott, Bennet, Graeme, Craig, Jamie E, Muecke, James S, Suthers, Graeme K

“…Congenital hypertrophy of the retinal pigment epithelium (CHRPE) is a pigmented fundus lesion associated with familial adenomatous polyposis (FAP). CHRPE…”
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Cancer Risks for Relatives of Patients With Serrated Polyposis by AUNG KO WIN, WALTERS, Rhiannon J, PEARSON, Sally-Ann, PAVLUK, Erika, NAGLER, Belinda, HOPPER, John L, GATTAS, Michael R, GOLDBLATT, Jack, GEORGE, Jill, SUTHERS, Graeme K, PHILLIPS, Kerry D, WOODALL, Sonja, BUCHANAN, Daniel D, ARNOLD, Julie, TUCKER, Kathy, FIELD, Michael, GREENING, Sian, GALLINGER, Steve, ARONSON, Melyssa, PERRIER, Renee, WOODS, Michael O, GREEN, Jane S, WALKER, Neal, JENKINS, Mark A, ROSTY, Christophe, PARRY, Susan, YOUNG, Joanne P, SWEET, Kevin, FRANKEL, Wendy L, DE LA CHAPELLE, Albert, MCKEONE, Diane M, WALSH, Michael D, CLENDENNING, Mark

“…Serrated polyposis (hyperplastic polyposis) is characterized by multiple polyps with serrated architecture in the colorectum. Although patients with serrated…”
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Lynch Syndrome―Associated Breast Cancers: Clinicopathologic Characteristics of a Case Series from the Colon Cancer Family Registry by WASH, Michael D, BUCHANAN, Daniel D, JENKINS, Mark A, PHILLIPS, Kerry D, SUTHERS, Graeme K, GEORGE, Jill, GOLDBLATT, Jack, MUIR, Amanda, TUCKER, Kathy, PELZER, Elise, GATTAS, Michael R, WOODALL, Sonja, CUMMINGS, Margaret C, PARRY, Susan, MACRAE, Finlay A, HAILE, Robert W, BARON, John A, POTTER, John D, LE MARCHAND, Loic, BAPAT, Bharati, THIBODEAU, Stephen N, LINDOR, Noralane M, MCGUCKIN, Michael A, PEARSON, Sally-Ann, YOUNG, Joanne P, ARNOLD, Sven T, CLENDENNING, Mark, WALTERS, Rhiannon, MCKEONE, Diane M, SPURDLE, Amanda B, HOPPER, John L

“…The recognition of breast cancer as a spectrum tumor in Lynch syndrome remains controversial. The aim of this study was to explore features of breast cancers…”
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Alerting genetic relatives to a risk of serious inherited disease without a patient's consent by Suthers, Graeme K, McCusker, Elizabeth A, Wake, Samantha A

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CANCER RISKS FOR AUSTRALIAN WOMEN WITH A BRCA1 OR A BRCA2 MUTATION by Suthers, Graeme K.

“…One of the primary purposes of genetic testing for mutations in the BRCA1 and BRCA2 genes in patients with familial breast/ovarian cancer has been to provide…”
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Doctors breaching patient privacy: Orwell redux by Suthers, Graeme K, McCusker, Elizabeth A, Wake, Samantha A

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Phenotypic diversity in patients with multiple serrated polyps: a genetics clinic study by Buchanan, Daniel D, Sweet, Kevin, Drini, Musa, Jenkins, Mark A, Win, Aung Ko, Gattas, Michael, Walsh, Michael D, Clendenning, Mark, McKeone, Diane, Walters, Rhiannon, Roberts, Aedan, Young, Alasdair, Hampel, Heather, Hopper, John L, Goldblatt, Jack, George, Jill, Suthers, Graeme K, Phillips, Kerry, Young, Graeme P, Chow, Elizabeth, Parry, Susan, Woodall, Sonja, Tucker, Kathy, Muir, Amanda, Field, Michael, Greening, Sian, Gallinger, Steven, Green, Jane, Woods, Michael O, Spaetgens, Renee, de la Chapelle, Albert, Macrae, Finlay, Walker, Neal I, Jass, Jeremy R, Young, Joanne P

“…Objective Hyperplastic polyposis is a colonic polyposis condition of unknown aetiology. The purpose of this study was to examine the spectrum of phenotypic…”
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Lynch syndrome-associated breast cancers do not overexpress chromosome 11-encoded mucins by Walsh, Michael D, Cummings, Margaret C, Pearson, Sally-Ann, Clendenning, Mark, Walters, Rhiannon J, Nagler, Belinda, Hopper, John L, Jenkins, Mark A, Suthers, Graeme K, Goldblatt, Jack, Tucker, Kathy, Gattas, Michael R, Arnold, Julie L, Parry, Susan, Macrae, Finlay A, McGuckin, Michael A, Young, Joanne P, Buchanan, Daniel D

“…Mismatch repair-deficient breast cancers may be identified in Lynch syndrome mutation carriers, and have clinicopathological features in common with mismatch…”
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New mutations in MID1 provide support for loss of function as the cause of X-linked Opitz syndrome by COX, Timothy C, ALLEN, Lillian R, COX, Liza L, HOPWOOD, Blair, GOODWIN, Bruce, HAAN, Eric, SUTHERS, Graeme K

“…Opitz syndrome (OS) is a genetically heterogeneous malformation disorder. Patients with OS may present with a variable array of malformations that are…”
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Linkage to chromosome 2q32.2-q33.3 in familial serrated neoplasia (Jass syndrome) by Roberts, Aedan, Nancarrow, Derek, Clendenning, Mark, Buchanan, Daniel D., Jenkins, Mark A., Duggan, David, Taverna, Darin, McKeone, Diane, Walters, Rhiannon, Walsh, Michael D., Young, Bruce W., Jass, Jeremy R., Rosty, Christophe, Gattas, Michael, Pelzer, Elise, Hopper, John L., Goldblatt, Jack, George, Jill, Suthers, Graeme K., Phillips, Kerry, Parry, Susan, Woodall, Sonja, Arnold, Julie, Tucker, Kathy, Muir, Amanda, Drini, Musa, Macrae, Finlay, Newcomb, Polly, Potter, John D., Pavluk, Erika, Lindblom, Annika, Young, Joanne P.

“…Causative genetic variants have to date been identified for only a small proportion of familial colorectal cancer (CRC). While conditions such as Familial…”
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Analysis of families with Lynch syndrome complicated by advanced serrated neoplasia: the importance of pathology review and pedigree analysis by Walsh, Michael D., Buchanan, Daniel D., Walters, Rhiannon, Roberts, Aedan, Arnold, Sven, McKeone, Diane, Clendenning, Mark, Ruszkiewicz, Andrew R., Jenkins, Mark A., Hopper, John L., Goldblatt, Jack, George, Jillian, Suthers, Graeme K., Phillips, Kerry, Young, Graeme P., Macrae, Finlay, Drini, Musa, Woods, Michael O., Parry, Susan, Jass, Jeremy R., Young, Joanne P.

“…The identification of Lynch syndrome has been greatly assisted by the advent of tumour immunohistochemistry (IHC) for mismatch repair (MMR) proteins, and by…”
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Erratum to: Phenotypic diversity in patients with multiple serrated polyps: a genetics clinic study by Buchanan, Daniel D., Sweet, Kevin, Drini, Musa, Jenkins, Mark A., Win, Aung Ko, Gattas, Michael, Walsh, Michael D., Clendenning, Mark, McKeone, Diane, Walters, Rhiannon, Roberts, Aedan, Young, Alasdair, Hampel, Heather, Hopper, John L., Goldblatt, Jack, George, Jill, Suthers, Graeme K., Phillips, Kerry, Young, Graeme P., Chow, Elizabeth, Parry, Susan, Woodall, Sonja, Tucker, Kathy, Muir, Amanda, Field, Michael, Greening, Sian, Gallinger, Steven, Green, Jane, Woods, Michael O., Spaetgens, Renee, de la Chapelle, Albert, Macrae, Finlay, Walker, Neal I., Jass, Jeremy R., Young, Joanne P.

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Point Mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant by Li, Jun, Woods, Susan L., Healey, Sue, Beesley, Jonathan, Chen, Xiaoqing, Lee, Jason S., Sivakumaran, Haran, Wayte, Nicci, Nones, Katia, Waterfall, Joshua J., Pearson, John, Patch, Anne-Marie, Senz, Janine, Ferreira, Manuel A., Kaurah, Pardeep, Mackenzie, Robertson, Heravi-Moussavi, Alireza, Hansford, Samantha, Lannagan, Tamsin R.M., Spurdle, Amanda B., Simpson, Peter T., da Silva, Leonard, Lakhani, Sunil R., Clouston, Andrew D., Bettington, Mark, Grimpen, Florian, Busuttil, Rita A., Di Costanzo, Natasha, Boussioutas, Alex, Jeanjean, Marie, Chong, George, Fabre, Aurélie, Olschwang, Sylviane, Faulkner, Geoffrey J., Bellos, Evangelos, Coin, Lachlan, Rioux, Kevin, Bathe, Oliver F., Wen, Xiaogang, Martin, Hilary C., Neklason, Deborah W., Davis, Sean R., Walker, Robert L., Calzone, Kathleen A., Avital, Itzhak, Heller, Theo, Koh, Christopher, Pineda, Marbin, Rudloff, Udo, Quezado, Martha, Pichurin, Pavel N., Hulick, Peter J., Weissman, Scott M., Newlin, Anna, Rubinstein, Wendy S., Sampson, Jone E., Hamman, Kelly, Goldgar, David, Poplawski, Nicola, Phillips, Kerry, Schofield, Lyn, Armstrong, Jacqueline, Kiraly-Borri, Cathy, Suthers, Graeme K., Huntsman, David G., Foulkes, William D., Carneiro, Fatima, Lindor, Noralane M., Edwards, Stacey L., French, Juliet D., Waddell, Nicola, Meltzer, Paul S., Worthley, Daniel L., Schrader, Kasmintan A., Chenevix-Trench, Georgia

“…Gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) is an autosomal-dominant cancer-predisposition syndrome with a significant risk of…”
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