Search Results - "Sutherland, L R"

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  1. 1

    The prognostic and predictive value of serum CA19.9 in pancreatic cancer by Humphris, J.L., Chang, D.K., Johns, A.L., Scarlett, C.J., Pajic, M., Jones, M.D., Colvin, E.K., Nagrial, A., Chin, V.T., Chantrill, L.A., Samra, J.S., Gill, A.J., Kench, J.G., Merrett, N.D., Das, A., Musgrove, E.A., Sutherland, R.L., Biankin, A.V.

    Published in Annals of oncology (01-07-2012)
    “…Current staging methods for pancreatic cancer (PC) are inadequate, and biomarkers to aid clinical decision making are lacking. Despite the availability of the…”
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  2. 2

    A role for GATA-2 in transition to an aggressive phenotype in prostate cancer through modulation of key androgen-regulated genes by Böhm, M, Locke, W J, Sutherland, R L, Kench, J G, Henshall, S M

    Published in Oncogene (29-10-2009)
    “…GATA-2, a member of the GATA family of transcription factors, is involved in androgen receptor (AR) signaling, however, little is known regarding its role in…”
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  3. 3

    Adjuvant chemotherapy in elderly patients with pancreatic cancer by Nagrial, A M, Chang, D K, Nguyen, N Q, Johns, A L, Chantrill, L A, Humphris, J L, Chin, V T, Samra, J S, Gill, A J, Pajic, M, Pinese, M, Colvin, E K, Scarlett, C J, Chou, A, Kench, J G, Sutherland, R L, Horvath, L G, Biankin, A V

    Published in British journal of cancer (21-01-2014)
    “…Background: Adjuvant chemotherapy improves survival for patients with resected pancreatic cancer. Elderly patients are under-represented in Phase III clinical…”
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  4. 4

    Prediction of outcome of early ER+ breast cancer is improved using a biomarker panel, which includes Ki-67 and p53 by Millar, E K A, Graham, P H, McNeil, C M, Browne, L, O'Toole, S A, Boulghourjian, A, Kearsley, J H, Papadatos, G, Delaney, G, Fox, C, Nasser, E, Capp, A, Sutherland, R L

    Published in British journal of cancer (12-07-2011)
    “…Background: The aim of this study is to determine whether immunohistochemical (IHC) assessment of Ki67 and p53 improves prognostication of oestrogen…”
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  5. 5

    Estrogen and antiestrogen regulation of cell cycle progression in breast cancer cells by Doisneau-Sixou, S F, Sergio, C M, Carroll, J S, Hui, R, Musgrove, E A, Sutherland, R L

    Published in Endocrine-related cancer (01-06-2003)
    “…The central involvement of estrogen in the development of the mammary gland and in the genesis of breast cancer has lent impetus to studies of the links…”
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  6. 6

    Cyclin D1b protein expression in breast cancer is independent of cyclin D1a and associated with poor disease outcome by Millar, E K A, Dean, J L, McNeil, C M, O'Toole, S A, Henshall, S M, Tran, T, Lin, J, Quong, A, Comstock, C E S, Witkiewicz, A, Musgrove, E A, Rui, H, LeMarchand, L, Setiawan, V W, Haiman, C A, Knudsen, K E, Sutherland, R L, Knudsen, E S

    Published in Oncogene (16-04-2009)
    “…Aberrant expression of cyclin D1 protein is a common feature of breast cancer. However, the CCND1 gene encodes two gene products, cyclin D1a and cyclin D1b,…”
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  7. 7

    A distinct molecular profile associated with mucinous epithelial ovarian cancer by HEINZELMANN-SCHWARZ, V. A, GARDINER-GARDEN, M, FINK, D, HACKER, N. F, SUTHERLAND, R. L, O'BRIEN, P. M, HENSHALL, S. M, SCURRY, J. P, SCOLYER, R. A, SMITH, A. N, BALI, A, VANDEN BERGH, P, BARON-HAY, S, SCOTT, C

    Published in British journal of cancer (27-03-2006)
    “…Mucinous epithelial ovarian cancers (MOC) are clinically and morphologically distinct from the other histological subtypes of ovarian cancer. To determine the…”
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  8. 8

    Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells by McCloy, R A, Shelley, E J, Roberts, C G, Boslem, E, Biden, T J, Nicholson, R I, Gee, J M, Sutherland, R L, Musgrove, E A, Burgess, A, Butt, A J

    Published in British journal of cancer (10-12-2013)
    “…Background: Persin is a plant toxin that displays synergistic cytotoxicity with tamoxifen in human breast cancer cell lines. Here, we examined the ability of…”
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  9. 9

    Collagen and calcium-binding EGF domains 1 is frequently inactivated in ovarian cancer by aberrant promoter hypermethylation and modulates cell migration and survival by Barton, C A, Gloss, B S, Qu, W, Statham, A L, Hacker, N F, Sutherland, R L, Clark, S J, O'Brien, P M

    Published in British journal of cancer (05-01-2010)
    “…Background: Collagen and calcium-binding EGF domains 1 (CCBE1) is an uncharacterised gene that has down-regulated expression in breast cancer. As CCBE1 maps to…”
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  10. 10

    Promoter methylation of the mutated in colorectal cancer gene is a frequent early event in colorectal cancer by KOHONEN-CORISH, M. R. J, SIGGLEKOW, N. D, YOUNG, J, LEGGETT, B. A, JASS, J. R, SUTHERLAND, R. L, SUSANTO, J, CHAPUIS, P. H, BOKEY, E. L, DENT, O. F, CHAN, C, LIN, B. P. C, SENG, T. J, LAIRD, P. W

    Published in Oncogene (28-06-2007)
    “…The mutated in colorectal cancer (MCC) gene is in close linkage with the adenomatous polyposis coli (APC) gene on chromosome 5, in a region of frequent loss of…”
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  11. 11

    BAG-1 overexpression attenuates luminal apoptosis in MCF-10A mammary epithelial cells through enhanced RAF-1 activation by Anderson, L R, Sutherland, R L, Butt, A J

    Published in Oncogene (28-01-2010)
    “…Although the multi-functional, prosurvival protein, Bcl-2-associated anthanogene 1 (BAG-1) is frequently overexpressed in breast cancers, its role in the…”
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    Oral contraceptive use and smoking are risk factors for relapse in Crohn's disease by Timmer, Antje, Sutherland ,‡, Lloyd R., Martin §, Francois

    Published in Gastroenterology (New York, N.Y. 1943) (01-06-1998)
    “…Background & Aims: Lifestyle factors have been shown to influence prognosis in Crohn's disease. The purpose of this study was to prospectively assess the…”
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  14. 14

    Dynamic Lasing from All-Organic Two-Dimensional Photonic Crystals by Jakubiak, R., Tondiglia, V. P., Natarajan, L. V., Sutherland, R. L., Lloyd, P., Bunning, T. J., Vaia, R. A.

    Published in Advanced materials (Weinheim) (05-12-2005)
    “…Optically pumped lasing of pyrromethene 597 in 2D columnar photonic crystals (PCs) derived from holographic polymer‐dispersed liquid crystals (LCs, see Figure)…”
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  15. 15

    Prognostic significance of DNA repair proteins MLH1, MSH2 and MGMT expression in non-small-cell lung cancer and precursor lesions by Cooper, W A, Kohonen-Corish, M R J, Chan, C, Kwun, S Y, McCaughan, B, Kennedy, C, Sutherland, R L, Lee, C-S

    Published in Histopathology (01-04-2008)
    “…Aims:  To investigate the role of DNA repair proteins and their prognostic significance in non‐small‐cell lung cancer (NSCLC). Methods and results:  A…”
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    The influence of surfactant in reflective HPDLC gratings by Klosterman, J., Natarajan, L.V., Tondiglia, V.P., Sutherland, R.L., White, T.J., Guymon, C.A., Bunning, T.J.

    Published in Polymer (Guilford) (29-09-2004)
    “…The use of highly functional acrylate monomers (large number of reactive bonds) as the precursor to the polymer-rich phase of holographic polymer-dispersed…”
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  19. 19

    Wilms' tumor protein 1: an early target of progestin regulation in T-47D breast cancer cells that modulates proliferation and differentiation by Caldon, C E, Lee, C S L, Sutherland, R L, Musgrove, E A

    Published in Oncogene (03-01-2008)
    “…Progesterone regulates the proliferation and differentiation of normal mammary epithelium. In breast cancer cells, progesterone and its synthetic analogs,…”
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  20. 20

    Aberrant p16(INK4A) and DPC4/Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma by Biankin, A V, Biankin, S A, Kench, J G, Morey, A L, Lee, C-S, Head, D R, Eckstein, R P, Hugh, T B, Henshall, S M, Sutherland, R L

    Published in Gut (01-06-2002)
    “…Intraductal papillary mucinous tumours (IPMT) of the pancreas constitute a unique pathological entity with an overall incidence of associated invasive…”
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