Search Results - "Sutherland, Colin"

Persistent Parasitism: The Adaptive Biology of Malariae and Ovale Malaria by Sutherland, Colin J

“…Plasmodium malariae causes malaria in humans throughout the tropics and subtropics. Plasmodium ovale curtisi and Plasmodium ovale wallikeri are sympatric…”
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A New Window on Plasmodium malariae Infections by Sutherland, Colin J

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Artemisinin susceptibility in the malaria parasite Plasmodium falciparum: propellers, adaptor proteins and the need for cellular healing by Sutherland, Colin J, Henrici, Ryan C, Artavanis-Tsakonas, Katerina

“…ABSTRACT Studies of the susceptibility of Plasmodium falciparum to the artemisinin family of antimalarial drugs provide a complex picture of partial resistance…”
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Modification of pfap2μ and pfubp1 Markedly Reduces Ring-Stage Susceptibility of Plasmodium falciparum to Artemisinin In Vitro by Henrici, Ryan C, van Schalkwyk, Donelly A, Sutherland, Colin J

“…Management of uncomplicated malaria worldwide is threatened by the emergence in Asia of carrying variants of the locus and exhibiting reduced susceptibility to…”
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The primate malaria parasites Plasmodium malariae, Plasmodium brasilianum and Plasmodium ovale spp.: genomic insights into distribution, dispersal and host transitions by Fuehrer, Hans-Peter, Campino, Susana, Sutherland, Colin J

“…During the twentieth century, there was an explosion in understanding of the malaria parasites infecting humans and wild primates. This was built on three main…”
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Genetic diversity of the Plasmodium falciparum GTP-cyclohydrolase 1, dihydrofolate reductase and dihydropteroate synthetase genes reveals new insights into sulfadoxine-pyrimethamine antimalarial drug resistance by Turkiewicz, Anna, Manko, Emilia, Sutherland, Colin J, Diez Benavente, Ernest, Campino, Susana, Clark, Taane G

“…Plasmodium falciparum parasites resistant to antimalarial treatments have hindered malaria disease control. Sulfadoxine-pyrimethamine (SP) was used globally as…”
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Paper-Origami-Based Multiplexed Malaria Diagnostics from Whole Blood by Xu, Gaolian, Nolder, Debbie, Reboud, Julien, Oguike, Mary C., van Schalkwyk, Donelly A., Sutherland, Colin J., Cooper, Jonathan M.

“…We demonstrate, for the first time, the multiplexed determination of microbial species from whole blood using the paper‐folding technique of origami to enable…”
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Calling them names: variants of Plasmodium ovale by Šlapeta, Jan, Sutherland, Colin J., Fuehrer, Hans-Peter

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Contribution of Plasmodium knowlesi to Multispecies Human Malaria Infections in North Sumatera, Indonesia by Lubis, Inke N. D., Wijaya, Hendri, Lubis, Munar, Lubis, Chairuddin P., Divis, Paul C. S., Beshir, Khalid B., Sutherland, Colin J.

“…Background. As Indonesia works toward the goal of malaria elimination, information is lacking on malaria epidemiology from some western provinces. As a basis…”
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Highly Sensitive Detection of Malaria Parasitemia in a Malaria-Endemic Setting: Performance of a New Loop-Mediated Isothermal Amplification Kit in a Remote Clinic in Uganda by Hopkins, Heidi, González, Iveth J., Polley, Spencer D., Angutoko, Patrick, Ategeka, John, Asiimwe, Caroline, Agaba, Bosco, Kyabayinze, Daniel J., Sutherland, Colin J., Perkins, Mark D., Bell, David

“…Background. Current malaria diagnostic tests, including microscopy and antigen-detecting rapid tests, cannot reliably detect low-density infections. Molecular…”
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Artemisinin resistance-associated markers in Plasmodium falciparum parasites from the China-Myanmar border: predicted structural stability of K13 propeller variants detected in a low-prevalence area by He, Yan, Campino, Susana, Diez Benavente, Ernest, Warhurst, David C, Beshir, Khalid B, Lubis, Inke, Gomes, Ana Rita, Feng, Jun, Jiazhi, Wang, Sun, Xiaodong, Huang, Fang, Tang, Lin-Hua, Sutherland, Colin J, Clark, Taane G

“…Malaria reduction and future elimination in China is made more difficult by the importation of cases from neighboring endemic countries, particularly Myanmar,…”
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Reply to van der Pluijm et al., "Antimalarial Resistance Unlikely To Explain U.K. Artemether-Lumefantrine Failures" by Sutherland, Colin J

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A molecular barcode to inform the geographical origin and transmission dynamics of Plasmodium vivax malaria by Diez Benavente, Ernest, Campos, Monica, Phelan, Jody, Nolder, Debbie, Dombrowski, Jamille G, Marinho, Claudio R F, Sriprawat, Kanlaya, Taylor, Aimee R, Watson, James, Roper, Cally, Nosten, Francois, Sutherland, Colin J, Campino, Susana, Clark, Taane G

“…Although Plasmodium vivax parasites are the predominant cause of malaria outside of sub-Saharan Africa, they not always prioritised by elimination programmes…”
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Genomic variation in Plasmodium vivax malaria reveals regions under selective pressure by Diez Benavente, Ernest, Ward, Zoe, Chan, Wilson, Mohareb, Fady R, Sutherland, Colin J, Roper, Cally, Campino, Susana, Clark, Taane G

“…Although Plasmodium vivax contributes to almost half of all malaria cases outside Africa, it has been relatively neglected compared to the more deadly P…”
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Mammalian malaria: Remembering the Alamo by Sutherland, Colin J.

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A genetic intervention by Sutherland, Colin, Menard, Didier

“…A tool that analyzes the genome of parasites found in the blood of malaria patients can help inform policy decisions on how best to tackle the rise in…”
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The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis by Mousa, Andria, Al-Taiar, Abdullah, Anstey, Nicholas M, Badaut, Cyril, Barber, Bridget E, Bassat, Quique, Challenger, Joseph D, Cunnington, Aubrey J, Datta, Dibyadyuti, Drakeley, Chris, Ghani, Azra C, Gordeuk, Victor R, Grigg, Matthew J, Hugo, Pierre, John, Chandy C, Mayor, Alfredo, Migot-Nabias, Florence, Opoka, Robert O, Pasvol, Geoffrey, Rees, Claire, Reyburn, Hugh, Riley, Eleanor M, Shah, Binal N, Sitoe, Antonio, Sutherland, Colin J, Thuma, Philip E, Unger, Stefan A, Viwami, Firmine, Walther, Michael, Whitty, Christopher J M, William, Timothy, Okell, Lucy C

“…Delay in receiving treatment for uncomplicated malaria (UM) is often reported to increase the risk of developing severe malaria (SM), but access to treatment…”
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The Role of Ultrasensitive Molecular Methods for Detecting Malaria—The Broader Perspective by Kamaliddin, Claire, Sutherland, Colin J, Houze, Sandrine, Cottrell, Gilles, Briand, Valerie, Castaneda Mogollon, Daniel, Pillai, Dylan R

“…Abstract Ultrasensitive molecular diagnostics are lowering the limit of detection for malaria parasites in the blood and providing insights not captured by…”
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Alternative pathway to reduced artemisinin susceptibility in Plasmodium falciparum by Henrici, Ryan C., Sutherland, Colin J.

“…Malaria case management across endemic regions of the globe relies on artemisinin (ART) combination therapies for the rapid treatment of acute Plasmodium…”
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Plasmodium-associated changes in human odor attract mosquitoes by Robinson, Ailie, Busula, Annette O., Voets, Mirjam A., Beshir, Khalid B., Caulfield, John C., Powers, Stephen J., Verhulst, Niels O., Winskill, Peter, Muwanguzi, Julian, Birkett, Michael A., Smallegange, Renate C., Masiga, Daniel K., Mukabana, W. Richard, Sauerwein, Robert W., Sutherland, Colin J., Bousema, Teun, Pickett, John A., Takken, Willem, Logan, James G., de Boer, Jetske G.

“…Malaria parasites (Plasmodium) can change the attractiveness of their vertebrate hosts to Anopheles vectors, leading to a greater number of vector–host…”
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