Search Results - "Suter, Marc R."

p38 MAPK, Microglial Signaling, and Neuropathic Pain by Ji, Ru-Rong, Suter, Marc R

“…Accumulating evidence over last several years indicates an important role of microglial cells in the pathogenesis of neuropathic pain. Signal transduction in…”
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JNK-Induced MCP-1 Production in Spinal Cord Astrocytes Contributes to Central Sensitization and Neuropathic Pain by Gao, Yong-Jing, Zhang, Ling, Samad, Omar Abdel, Suter, Marc R, Yasuhiko, Kawasaki, Xu, Zhen-Zhong, Park, Jong-Yeon, Lind, Anne-Li, Ma, Qiufu, Ji, Ru-Rong

“…Our previous study showed that activation of c-jun-N-terminal kinase (JNK) in spinal astrocytes plays an important role in neuropathic pain sensitization. We…”
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Glial Cells and Chronic Pain by Gosselin, Romain-Daniel, Suter, Marc R., Ji, Ru-Rong, Decosterd, Isabelle

“…Over the past few years, the control of pain exerted by glial cells has emerged as a promising target against pathological pain. Indeed, changes in glial…”
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Characterisation of GFAP-Expressing Glial Cells in the Dorsal Root Ganglion after Spared Nerve Injury by Konnova, Elena A, Deftu, Alexandru-Florian, Chu Sin Chung, Paul, Pertin, Marie, Kirschmann, Guylène, Decosterd, Isabelle, Suter, Marc R

“…Satellite glial cells (SGCs), enveloping primary sensory neurons' somas in the dorsal root ganglion (DRG), contribute to neuropathic pain upon nerve injury…”
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Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia by Wen, Yeong-Ray, Suter, Marc R, Ji, Ru-Rong, Yeh, Geng-Chang, Wu, Yen-Sheng, Wang, Kuo-Ching, Kohno, Tatsuro, Sun, Wei-Zen, Wang, Chia-Chuan

“…Recent studies have implicated the activation of stress-activated mitogen-activated protein kinase (MAPK) p38 in spinal microglial cells for development of…”
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Somatosensory profiling of patients undergoing alcohol withdrawal: do neuropathic pain and sensory loss represent a problem? by Fernandez, Aurore, Graf, Guillaume, Lasserre, Aurélie, Daeppen, Jean-Bernard, Chung, Paul Chu Sin, Berna, Chantal, Suter, Marc R

“…Chronic heavy alcohol use is known to cause neurological complications such as peripheral neuropathy. Concerning the pathophysiology, few sural nerve and skin…”
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A test of positive suggestions about side effects as a way of enhancing the analgesic response to NSAIDs by Fernandez, Aurore, Kirsch, Irving, Noël, Louis, Rodondi, Pierre Yves, Kaptchuk, Ted J, Suter, Marc R, Décosterd, Isabelle, Berna, Chantal

“…Side effects are frequent in pharmacological pain management, potentially preceding analgesia and limiting drug tolerability. Discussing side effects is part…”
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Neuropathic Pain Phenotype Does Not Involve the NLRP3 Inflammasome and Its End Product Interleukin-1β in the Mice Spared Nerve Injury Model by Curto-Reyes, Verdad, Kirschmann, Guylène, Pertin, Marie, Drexler, Stephan K, Decosterd, Isabelle, Suter, Marc R

“…The NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome is one of the main sources of interleukin-1β (IL-1β) and is involved in several…”
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Spinal Cord T-Cell Infiltration in the Rat Spared Nerve Injury Model: A Time Course Study by Gattlen, Christophe, Clarke, Christine B, Piller, Nicolas, Kirschmann, Guylène, Pertin, Marie, Decosterd, Isabelle, Gosselin, Romain-Daniel, Suter, Marc R

“…The immune system is involved in the development of neuropathic pain. In particular, the infiltration of T-lymphocytes into the spinal cord following…”
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Rufinamide Attenuates Mechanical Allodynia in a Model of Neuropathic Pain in the Mouse and Stabilizes Voltage-gated Sodium Channel Inactivated State by SUTER, Marc R, KIRSCHMANN, Guylène, LAEDERMANN, Cedric J, ABRIEL, Hugues, DECOSTERD, Isabelle

“…Voltage-gated sodium channels dysregulation is important for hyperexcitability leading to pain persistence. Sodium channel blockers currently used to treat…”
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Blocking Caspase Activity Prevents Transsynaptic Neuronal Apoptosis and the Loss of Inhibition in Lamina II of the Dorsal Horn after Peripheral Nerve Injury by Scholz, Joachim, Broom, Daniel C, Youn, Dong-Ho, Mills, Charles D, Kohno, Tatsuro, Suter, Marc R, Moore, Kimberly A, Decosterd, Isabelle, Coggeshall, Richard E, Woolf, Clifford J

“…We show that transsynaptic apoptosis is induced in the superficial dorsal horn (laminas I-III) of the spinal cord by three distinct partial peripheral nerve…”
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Large A-Fiber Activity is Required for Microglial Proliferation and P38 MAPK Activation in the Spinal Cord: Different Effects of Resiniferatoxin and Bupivacaine on Spinal Microglial Changes after Spared Nerve Injury by Suter, Marc R, Berta, Temugin, Gao, Yong-Jing, Decosterd, Isabelle, Ji, Ru-Rong

“…Background After peripheral nerve injury, spontaneous ectopic activity arising from the peripheral axons plays an important role in inducing central…”
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Nerve conduction blockade in the sciatic nerve prevents but does not reverse the activation of p38 mitogen-activated protein kinase in spinal microglia in the rat spared nerve injury model by WEN, Yeong-Ray, SUTER, Marc R, KAWASAKI, Yasuhiko, JIN HUANG, PERTIN, Marie, KOHNO, Tatsuro, BERDE, Charles B, DECOSTERD, Isabelle, JI, Ru-Rong

“…Current evidence indicates that p38 mitogen-activated protein kinase activation in spinal microglia contributes to the development of neuropathic pain…”
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Reverse transcription quantitative real-time polymerase chain reaction reference genes in the spared nerve injury model of neuropathic pain: validation and literature search by Piller, Nicolas, Decosterd, Isabelle, Suter, Marc R

“…The reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR) is a widely used, highly sensitive laboratory technique to rapidly and…”
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Microglial role in the development of chronic pain by Suter, Marc R

“…The review aims to present the latest research into microglia and their role in pain. Microglia affect sex and age-dependent differences in pain. The various…”
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Small fiber neuropathy in hypermobile Ehlers Danlos syndrome/hypermobility spectrum disorder by Fernandez, Aurore, Aubry‐Rozier, Bérengère, Vautey, Mathieu, Berna, Chantal, Suter, Marc R.

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Potassium channel modulation in macrophages sensitizes dorsal root ganglion neurons after nerve injury by Konnova, Elena A., Deftu, Alexandru‐Florian, Chu Sin Chung, Paul, Kirschmann, Guylène, Decosterd, Isabelle, Suter, Marc R.

“…Macrophages and satellite glial cells are found between injured and uninjured neurons in the lumbar dorsal root ganglia (DRG). We explored the mechanism of…”
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Microglial STING activation alleviates nerve injury-induced neuropathic pain in male but not female mice by Silveira Prudente, Arthur, Hoon Lee, Sang, Roh, Jueun, Luckemeyer, Debora D., Cohen, Cinder F., Pertin, Marie, Park, Chul-Kyu, Suter, Marc R., Decosterd, Isabelle, Zhang, Jun-Ming, Ji, Ru-Rong, Berta, Temugin

“…•Microglia contribute to the development and maintenance of neuropathic pain, highlighting a potential target for therapeutic intervention.•STING is…”
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Pain Intensity in the First 96 Hours After Abdominal Surgery: A Prospective Cohort Study by Cachemaille, Matthieu, Grass, Fabian, Fournier, Nicolas, Suter, Marc R, Demartines, Nicolas, Hübner, Martin, Blanc, Catherine

“…Abstract Objective Multimodal pain management strategies aim to improve postoperative pain control. The purpose of this study was to analyze pain scores and…”
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Prehospital Use of Ketamine in Mountain Rescue: A Survey of Emergency Physicians of a Single-Center Alpine Helicopter-Based Emergency Service by Vanolli, Katia, Hugli, Olivier, Eidenbenz, David, Suter, Marc R., Pasquier, Mathieu

“…Although ketamine use in emergency medicine is widespread, studies investigating prehospital use are scarce. Our goal was to assess the self-reported…”
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