Search Results - "Sutcliffe, Matthew"

Network-based predictions of in vivo cardiac hypertrophy by Frank, Deborah U., Sutcliffe, Matthew D., Saucerman, Jeffrey J.

“…Cardiac hypertrophy is a common response of cardiac myocytes to stress and a predictor of heart failure. While in vitro cell culture studies have identified…”
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Pan-Cancer Drivers Are Recurrent Transcriptional Regulatory Heterogeneities in Early-Stage Luminal Breast Cancer by Singh, Shambhavi, Sutcliffe, Matthew D, Repich, Kathy, Atkins, Kristen A, Harvey, Jennifer A, Janes, Kevin A

“…The heterogeneous composition of solid tumors is known to impact disease progression and response to therapy. Malignant cells coexist in different regulatory…”
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Premalignant Oligodendrocyte Precursor Cells Stall in a Heterogeneous State of Replication Stress Prior to Gliomagenesis by Sutcliffe, Matthew D, Galvao, Rui P, Wang, Lixin, Kim, Jungeun, Rosenfeld, Lauren K, Singh, Shambhavi, Zong, Hui, Janes, Kevin A

“…Cancer evolves from premalignant clones that adopt unusual cell states to achieve transformation. We previously pinpointed the oligodendrocyte precursor cell…”
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A Highly Selective Ethylene Tetramerization Catalyst by Shaikh, Yacoob, Albahily, Khalid, Sutcliffe, Matthew, Fomitcheva, Valeria, Gambarotta, Sandro, Korobkov, Ilia, Duchateau, Robbert

“…Small change, big difference: The introduction of an additional CH2 group into the bridge of ligands with two P/N units leads to a different selectivity of the…”
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Fragmentation of Small-Cell Lung Cancer Regulatory States in Heterotypic Microenvironments by Schaff, Dylan L, Singh, Shambhavi, Kim, Kee-Beom, Sutcliffe, Matthew D, Park, Kwon-Sik, Janes, Kevin A

“…Small-cell lung cancers derive from pulmonary neuroendocrine cells, which have stem-like properties to reprogram into other cell types upon lung injury. It is…”
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A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism by Enriquez-Hesles, Elisa, Smith, Daniel L., Maqani, Nazif, Wierman, Margaret B., Sutcliffe, Matthew D., Fine, Ryan D., Kalita, Agata, Santos, Sean M., Muehlbauer, Michael J., Bain, James R., Janes, Kevin A., Hartman, John L., Hirschey, Matthew D., Smith, Jeffrey S.

“…Caloric restriction (CR) improves health span and life span of organisms ranging from yeast to mammals. Understanding the mechanisms involved will uncover…”
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High content analysis identifies unique morphological features of reprogrammed cardiomyocytes by Sutcliffe, Matthew D., Tan, Philip M., Fernandez-Perez, Antonio, Nam, Young-Jae, Munshi, Nikhil V., Saucerman, Jeffrey J.

“…Direct reprogramming of fibroblasts into cardiomyocytes is a promising approach for cardiac regeneration but still faces challenges in efficiently generating…”
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In situ 10-cell RNA sequencing in tissue and tumor biopsy samples by Singh, Shambhavi, Wang, Lixin, Schaff, Dylan L., Sutcliffe, Matthew D., Koeppel, Alex F., Kim, Jungeun, Onengut-Gumuscu, Suna, Park, Kwon-Sik, Zong, Hui, Janes, Kevin A.

“…Single-cell transcriptomic methods classify new and existing cell types very effectively, but alternative approaches are needed to quantify the individual…”
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Procedurally Optimised ZX-Diagram Cutting for Efficient T-Decomposition in Classical Simulation by Sutcliffe, Matthew, Kissinger, Aleks

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Irritable bowel syndrome by Sutcliffe, Matthew

“…Irritable bowel syndrome (IBS) is a functional bowel disorder that commonly presents in primary care and has an array of symptoms including abdominal…”
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Smarter k-Partitioning of ZX-Diagrams for Improved Quantum Circuit Simulation by Sutcliffe, Matthew

“…We introduce a novel method for strong classical simulation of quantum circuits based on optimally k-partitioning ZX-diagrams, reducing each part individually,…”
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Procedurally Optimised ZX-Diagram Cutting for Efficient T-Decomposition in Classical Simulation by Sutcliffe, Matthew, Kissinger, Aleks

“…EPTCS 406, 2024, pp. 63-78 A quantum circuit may be strongly classically simulated with the aid of ZX-calculus by decomposing its $t$ T-gates into a sum of…”
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Fast classical simulation of quantum circuits via parametric rewriting in the ZX-calculus by Sutcliffe, Matthew, Kissinger, Aleks

“…The ZX-calculus is an algebraic formalism that allows quantum computations to be simplified via a small number of simple graphical rewrite rules. Recently, it…”
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A cell-nonautonomous mechanism of yeast chronological aging regulated by caloric restriction and one-carbon metabolism by Enriquez-Hesles, Elisa, Smith, Jr, Daniel L, Maqani, Nazif, Wierman, Margaret B, Sutcliffe, Matthew D, Fine, Ryan D, Kalita, Agata, Santos, Sean M, Muehlbauer, Michael J, Bain, James R, Janes, Kevin A, Hartman, 4th, John L, Hirschey, Matthew D, Smith, Jeffrey S

“…Caloric restriction (CR) improves health span and life span of organisms ranging from yeast to mammals. Understanding the mechanisms involved will uncover…”
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Will next year's rise in UK tuition fees change the demographic of future medical and dental students? by Kassamali, Rahil H., Mughal, Faraz, Faruque, Roohi, Kokotsis, Vasilis, Lee, Nikiesha, Pabla, Gurpreet, Song, Andrew, Spears, Maria, Sutcliffe, Matthew

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A Highly Selective Ethylene Tetramerization Catalyst by Shaikh, Yacoob, Albahily, Khalid, Sutcliffe, Matthew, Fomitcheva, Valeria, Gambarotta, Sandro, Korobkov, Ilia, Duchateau, Robbert

“…Kleine Änderung mit großer Wirkung: Die Einführung einer zusätzlichen CH2‐Gruppe in die Brücke von Liganden mit zwei P/N‐Einheiten führt zu unterschiedlichen…”
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A Highly Selective Ethylene Tetramerization Catalyst by Shaikh, Yacoob, Albahily, Khalid, Sutcliffe, Matthew, Fomitcheva, Valeria, Gambarotta, Sandro, Korobkov, Ilia, Duchateau, Robbert

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Adhesives Fasteners-Securing the Future by Sutcliffe, Matthew

“…ALTHOUGH adhesives may have been in use for centuries it is really only in the last 30 years that they have come of age in an industrial sense and challenged…”
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