Search Results - "Sutcliffe, J G"

The Hypocretins: Hypothalamus-Specific Peptides with Neuroexcitatory Activity by De Lecea, L., Kilduff, T. S., Peyron, C., X.-B. Gao, Foye, P. E., Danielson, P. E., Fukuhara, C., Battenberg, E. L. F., Gautvik, V. T., Bartlett, F. S., Frankel, W. N., Van Den Pol, A. N., Bloom, F. E., Gautvik, K. M., Sutcliffe, J. G.

“…We describe a hypothalamus-specific mRNA that encodes preprohypocretin, the putative precursor of a pair of peptides that share substantial amino acid…”
Get full text

No hypothermic response to serotonin in 5-HT7 receptor knockout mice by Hedlund, P B, Danielson, P E, Thomas, E A, Slanina, K, Carson, M J, Sutcliffe, J G

“…With data from recently available selective antagonists for the 5-HT 7 receptor, it has been hypothesized that 5-hydroxytryptamine (5-HT)-induced hypothermia…”
Get full text

Hypocretin/Orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and agouti gene-related protein systems by Broberger, C., De Lecea, L., Sutcliffe, J.G., Hökfelt, T.

“…Cells in the lateral hypothalamus and in the arcuate nucleus play prominent roles in the central control of food intake; however, a neurochemical link…”
Get full text

Hypocretin-1 Modulates Rapid Eye Movement Sleep through Activation of Locus Coeruleus Neurons by Bourgin, Patrice, Huitron-Resendiz, Salvador, Spier, Avron D, Fabre, Veronique, Morte, Beatriz, Criado, Jose R, Sutcliffe, J. Gregor, Henriksen, Steven J, de Lecea, Luis

“…The hypocretins (hcrts), also known as orexins, are two recently identified excitatory neuropeptides that in rat are produced by approximately 1200 neurons…”
Get full text

Antipsychotic drug treatment alters expression of mRNAs encoding lipid metabolism-related proteins by THOMAS, E. A, GEORGE, R. C, DANIELSON, P. E, NELSON, P. A, WARREN, A. J, LO, D, SUTCLIFFE, J. Gregor

“…Using an automated PCR-based genomics approach, TOtal Gene expression Analysis (TOGA), we have examined gene expression profiles of mouse striatum and frontal…”
Get full text

Differences in neuroanatomical sites of apoD elevation discriminate between schizophrenia and bipolar disorder by THOMAS, E. A, DEAN, B, SCARR, E, COPOLOV, D, SUTCLIFFE, J. G

“…We previously demonstrated that apolipoprotein D (apoD) levels are elevated in the dorsolateral prefrontal cortex and caudate obtained postmortem from subjects…”
Get full text

Mature microglia resemble immature antigen-presenting cells by Carson, Monica J., Reilly, Christina R., Sutcliffe, J. Gregor, Lo, David

“…Owing to the difficulties of isolating adequate numbers of microglia from adult tissue, much of our understanding of their function is based on…”
Get full text

Leptin receptor- and STAT3-immunoreactivities in hypocretin/orexin neurones of the lateral hypothalamus by Håkansson, M, de Lecea, L, Sutcliffe, J G, Yanagisawa, M, Meister, B

“…Hypocretins/orexins are recently characterized peptides that are synthesized in neurones of the lateral hypohalamus and stimulate food intake in rats. To…”
Get full text

The hypocretins/orexins: novel hypothalamic neuropeptides involved in different physiological systems by de Lecea, L, Sutcliffe, J G

“…The hypothalamus regulates diverse physiological functions, including the control of energy metabolism, circadian rhythms, stress and anxiety, sexual and…”
Get full text

A cortical neuropeptide with neuronal depressant and sleep-modulating properties by de Lecea, Luis, Criado, José R, Prospero-Garcia, Óscar, Gautvik, Kaare M, Schweitzer, Paul, Danielson, Patria E, Dunlop, Charles L. M, Siggins, George R, Henriksen, Steven J, Sutcliffe, J. Gregor

“…Acetylcholine (ACh) plays a key role in the transitions between the different phases of sleep: Slow-wave sleep requires low ACh concentrations in the brain,…”
Get full text

Overview of the Most Prevalent Hypothalamus-Specific mRNAs, as Identified by Directional Tag PCR Subtraction by Gautvik, Kaare M., De Lecea, Luis, Gautvik, Vigdis T., Danielson, Patria E., Tranque, Pedro, Dopazo, Ana, Bloom, Floyd E., Sutcliffe, J. Gregor

“…We applied the directional tag PCR subtractive hybridization method to construct a rat hypothalamic cDNA library from which cerebellar and hippocampal…”
Get full text

Preprohypocretin (orexin) and prolactin-like immunoreactivity are coexpressed by neurons of the rat lateral hypothalamic area by Risold, P.Y, Griffond, B, Kilduff, T.S, Sutcliffe, J.G, Fellmann, D

“…Recently, two new neuropeptides named hypocretins I and II (Hcrt) have been described in the rat lateral hypothalamus. The distribution of the neurons…”
Get full text

Influenza virus-susceptible mice carry Mx genes with a large deletion or a nonsense mutation by STAEHELI, P, GROB, R, MEIER, E, SUTCLIFFE, J. G, HALLER, O

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

mRNA in the mammalian central nervous system by Sutcliffe, J G

Get full text

Disproportionate Recruitment of CD8 + T Cells into the Central Nervous System by Professional Antigen-Presenting Cells by Carson, Monica J., Reilly, Christina R., Sutcliffe, J. Gregor, Lo, David

“…Inappropriate immune responses, thought to exacerbate or even to initiate several types of central nervous system (CNS) neuropathology, could arise from…”
Get full text

The hypocretins: Setting the arousal threshold by Sutcliffe, J. Gregor, de Lecea, Luis

“…Over a short period in the late 1990s, three groups converged on the discovery of a neuropeptide system, centred in the dorsolateral hypothalamus, that…”
Get full text

From pharmacotherapy to pathophysiology: emerging mechanisms of apolipoprotein D in psychiatric disorders by Thomas, E A, Copolov, D L, Sutcliffe, J G

“…Apolipoprotein D (apoD) is an atypical plasma apolipoprotein and, based on its primary structure, it is a member of the lipocalin protein superfamily…”
Get more information

Localization of the Protein Kinase C Phosphorylation/Calmodulin-Binding Substrate RC3 in Dendritic Spines of Neostriatal Neurons by Watson, Joseph B., Sutcliffe, J. Gregor, Fisher, Robin S.

“…The rodent protein RC3 is expressed mainly by forebrain neurons during postnatal development and maturity. RC3 and its bovine homolog neurogranin/B-50…”
Get full text

An endoplasmic reticulum-specific cyclophilin by HASEL, K. W, GLASS, J. R, GODBOUT, M, SUTCLIFFE, J. G

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Cloning, mRNA Expression, and Chromosomal Mapping of Mouse and Human Preprocortistatin by de Lecea, Luis, Ruiz-Lozano, Pilar, Danielson, Patria E., Peelle-Kirley, Jessica, Foye, Pamela E., Frankel, Wayne N., Sutcliffe, J.Gregor

“…Cortistatin is a 14-residue putative neuropeptide with strong structural similarity to somatostatin and is expressed predominantly in cortical GABAergic…”
Get full text