Search Results - "Sutanto, Erika N"

ACE2 expression is elevated in airway epithelial cells from older and male healthy individuals but reduced in asthma by Wark, Peter A.B., Pathinayake, Prabuddha S., Kaiko, Gerard, Nichol, Kristy, Ali, Ayesha, Chen, Ling, Sutanto, Erika N., Garratt, Luke W., Sohal, Sukhwinder S., Lu, Wenying, Eapen, Mathew S., Oldmeadow, Christopher, Bartlett, Nathan, Reid, Andrew, Veerati, Punnam, Hsu, Alan C.‐Y., Looi, Kevin, Iosifidis, Thomas, Stick, Stephen M., Hansbro, Philip M., Kicic, Anthony

“…ACE2 is the primary receptor for SARS‐CoV‐2. We demonstrate that lower airway expression of ACE2 is increased in older adults and males. Lower ACE2 expression…”
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Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics by Martinovich, Kelly M., Iosifidis, Thomas, Buckley, Alysia G., Looi, Kevin, Ling, Kak-Ming, Sutanto, Erika N., Kicic-Starcevich, Elizabeth, Garratt, Luke W., Shaw, Nicole C., Montgomery, Samuel, Lannigan, Francis J., Knight, Darryl A., Kicic, Anthony, Stick, Stephen M.

“…Current limitations to primary cell expansion led us to test whether airway epithelial cells derived from healthy children and those with asthma and cystic…”
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DNA methylation profiles of airway epithelial cells and PBMCs from healthy, atopic and asthmatic children by Stefanowicz, Dorota, Hackett, Tillie-Louise, Garmaroudi, Farshid S, Günther, Oliver P, Neumann, Sarah, Sutanto, Erika N, Ling, Kak-Ming, Kobor, Michael S, Kicic, Anthony, Stick, Stephen M, Paré, Peter D, Knight, Darryl A

“…Allergic inflammation is commonly observed in a number of conditions that are associated with atopy including asthma, eczema and rhinitis. However, the…”
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Decreased Fibronectin Production Significantly Contributes to Dysregulated Repair of Asthmatic Epithelium by KICIC, Anthony, HALLSTRAND, Teal S, SUTANTO, Erika N, STEVENS, Paul T, KOBOR, Michael S, TAPLIN, Christopher, PARE, Peter D, BEYER, Richard P, STICK, Stephen M, KNIGHT, Darryl A

“…Damage to airway epithelium is followed by deposition of extracellular matrix (ECM) and migration of adjacent epithelial cells. We have shown that epithelial…”
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Rhinovirus Infection Drives Complex Host Airway Molecular Responses in Children With Cystic Fibrosis by Ling, Kak-Ming, Garratt, Luke W, Gill, Erin E, Lee, Amy H Y, Agudelo-Romero, Patricia, Sutanto, Erika N, Iosifidis, Thomas, Rosenow, Tim, Turvey, Stuart E, Lassmann, Timo, Hancock, Robert E W, Kicic, Anthony, Stick, Stephen M

“…Early-life viral infections are responsible for pulmonary exacerbations that can contribute to disease progression in young children with cystic fibrosis (CF)…”
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Accumulation mode particles and LPS exposure induce TLR-4 dependent and independent inflammatory responses in the lung by Fonceca, Angela M, Zosky, Graeme R, Bozanich, Elizabeth M, Sutanto, Erika N, Kicic, Anthony, McNamara, Paul S, Knight, Darryl A, Sly, Peter D, Turner, Debra J, Stick, Stephen M

“…Accumulation mode particles (AMP) are formed from engine combustion and make up the inhalable vapour cloud of ambient particulate matter pollution. Their small…”
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Assessment of p.Phe508del-CFTR functional restoration in pediatric primary cystic fibrosis airway epithelial cells by Sutanto, Erika N, Scaffidi, Amelia, Garratt, Luke W, Looi, Kevin, Foo, Clara J, Tessari, Michela A, Janssen, Richard A, Fischer, David F, Stick, Stephen M, Kicic, Anthony

“…Mutations in the cystic fibrosis transmembrane regulator (CFTR) gene can reduce function of the CFTR ion channel activity and impair cellular chloride…”
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Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability by Looi, Kevin, Troy, Niamh M., Garratt, Luke W., Iosifidis, Thomas, Bosco, Anthony, Buckley, Alysia G., Ling, Kak-Ming, Martinovich, Kelly M., Kicic-Starcevich, Elizabeth, Shaw, Nicole C., Sutanto, Erika N., Zosky, Graeme R., Rigby, Paul J., Larcombe, Alexander N., Knight, Darryl A., Kicic, Anthony, Stick, Stephen M.

“…Rationale: No studies have assessed the effects of human rhinovirus (HRV) infection on epithelial tight junctions (TJs) and resultant barrier function. Aim of…”
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Regional differences in susceptibiity of bronchial epithelium to mesenchymal transition and inhibition by the macrolide antibiotic azithromycin by Banerjee, Balarka, Musk, Michael, Sutanto, Erika N, Yerkovich, Stephanie T, Hopkins, Peter, Knight, Darryl A, Lindsey-Temple, Suzanna, Stick, Stephen M, Kicic, Anthony, Chambers, Daniel C

“…Dysregulated repair following epithelial injury is a key forerunner of disease in many organs, and the acquisition of a mesenchymal phenotype by the injured…”
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Cystic Fibrosis Clinical Isolates of Aspergillus fumigatus Induce Similar Muco-inflammatory Responses in Primary Airway Epithelial Cells by McLean, Samantha A., Cullen, Leilani, Gardam, Dianne J., Schofield, Craig J., Laucirica, Daniel R., Sutanto, Erika N., Ling, Kak-Ming, Stick, Stephen M., Peacock, Christopher S., Kicic, Anthony, Garratt, Luke W.

“…Aspergillus is increasingly associated with lung inflammation and mucus plugging in early cystic fibrosis (CF) disease during which conidia burden is low and…”
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The airway epithelium is a direct source of matrix degrading enzymes in bronchiolitis obliterans syndrome by Banerjee, Balarka, BSc, Ling, Kak-Ming, BSc (Hons), Sutanto, Erika N., PhD, Musk, Michael, MBBS, Yerkovich, Stephanie T., PhD, Hopkins, Peter M.A., MBBS, Stick, Stephen M., MBChB, PhD, Kicic, Anthony, PhD, Chambers, Daniel C., MBBS, MD

“…Background Long-term survival after lung transplantation is hindered by the development of bronchiolitis obliterans syndrome (BOS), and recent evidence…”
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Update on SLC6A14 in lung and gastrointestinal physiology and physiopathology: focus on cystic fibrosis by Ruffin, Manon, Mercier, Julia, Calmel, Claire, Mésinèle, Julie, Bigot, Jeanne, Sutanto, Erika N., Kicic, Anthony, Corvol, Harriet, Guillot, Loic

“…The solute carrier family 6 member 14 (SLC6A14) protein imports and concentrates all neutral amino acids as well as the two cationic acids lysine and arginine…”
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Matrix metalloproteinase activation by free neutrophil elastase contributes to bronchiectasis progression in early cystic fibrosis by Garratt, Luke W, Sutanto, Erika N, Ling, Kak-Ming, Looi, Kevin, Iosifidis, Thomas, Martinovich, Kelly M, Shaw, Nicole C, Kicic-Starcevich, Elizabeth, Knight, Darryl A, Ranganathan, Sarath, Stick, Stephen M, Kicic, Anthony

“…Neutrophil elastase is the most significant predictor of bronchiectasis in early-life cystic fibrosis; however, the causal link between neutrophil elastase and…”
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Successful establishment of primary small airway cell cultures in human lung transplantation by Banerjee, Balarka, Kicic, Anthony, Musk, Michael, Sutanto, Erika N, Stick, Stephen M, Chambers, Daniel C

“…The study of small airway diseases such as post-transplant bronchiolitis obliterans syndrome (BOS) is hampered by the difficulty in assessing peripheral airway…”
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Intrinsic Biochemical and Functional Differences in Bronchial Epithelial Cells of Children with Asthma by Kicic, Anthony, Sutanto, Erika N, Stevens, Paul T, Knight, Darryl A, Stick, Stephen M

“…Convincing evidence of epithelial damage and aberrant repair exists in adult asthmatic airways, even in the absence of inflammation. However, comparable…”
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Innate inflammatory responses of pediatric cystic fibrosis airway epithelial cells: effects of nonviral and viral stimulation by Sutanto, Erika N, Kicic, Anthony, Foo, Clara J, Stevens, Paul T, Mullane, David, Knight, Darryl A, Stick, Stephen M

“…There is controversy regarding whether cystic fibrosis (CF) airway epithelial cells (AECs) are intrinsically proinflammatory. The objective of the current…”
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Azithromycin Partially Mitigates Dysregulated Repair of Lung Allograft Small Airway Epithelium by Ling, Kak-Ming, Garratt, Luke W., Banerjee, Balarka, Lavender, Melanie A., Wrobel, Jeremy P., Musk, Michael, Martinovich, Kelly M., Shaw, Nicole C., Iosifidis, Thomas, Looi, Kevin, Kicic-Starcevich, Elizabeth, Sutanto, Erika N., Yerkovich, Stephanie T., Chambers, Daniel C., Stick, Stephen M., Kicic, Anthony

“…BACKGROUND.Dysregulated airway epithelial repair following injury is a proposed mechanism driving posttransplant bronchiolitis obliterans (BO), and its…”
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Alpha-1 Antitrypsin Mitigates the Inhibition of Airway Epithelial Cell Repair by Neutrophil Elastase by Garratt, Luke W, Sutanto, Erika N, Ling, Kak-Ming, Looi, Kevin, Iosifidis, Thomas, Martinovich, Kelly M, Shaw, Nicole C, Buckley, Alysia G, Kicic-Starcevich, Elizabeth, Lannigan, Francis J, Knight, Darryl A, Stick, Stephen M, Kicic, Anthony

“…Neutrophil elastase (NE) activity is associated with many destructive lung diseases and is a predictor for structural lung damage in early cystic fibrosis…”
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Ivacaftor or lumacaftor/ivacaftor treatment does not alter the core CF airway epithelial gene response to rhinovirus by De Jong, Emma, Garratt, Luke W., Looi, Kevin, Lee, Amy H.Y., Ling, Kak-Ming, Smith, Maren L., Falsafi, Reza, Sutanto, Erika N., Hillas, Jessica, Iosifidis, Thomas, Martinovich, Kelly M., Shaw, Nicole C., Montgomery, Samuel T., Kicic-Starcevich, Elizabeth, Lannigan, Francis J., Vijayasekaran, Shyan, Hancock, Robert E.W., Stick, Stephen M., Kicic, Anthony, AREST, CF

“…•Measured gene responses by primary CF epithelial cells to rhinovirus using RNAseq.•Both P.Phe508del homozygous and P.Phe508del/pGly551Asp cells were…”
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Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells by Buckley, Alysia G, Looi, Kevin, Iosifidis, Thomas, Ling, Kak-Ming, Sutanto, Erika N, Martinovich, Kelly M, Kicic-Starcevich, Elizabeth, Garratt, Luke W, Shaw, Nicole C, Lannigan, Francis J, Larcombe, Alexander N, Zosky, Graeme, Knight, Darryl A, Rigby, Paul J, Kicic, Anthony, Stick, Stephen M

“…Apically located tight junctions in airway epithelium perform a fundamental role in controlling macromolecule migration through paracellular spaces…”
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