Search Results - "Sussman, N B"

The Utility of Structure-Activity Relationship (SAR) Models for Prediction and Covariate Selection in Developmental Toxicity: Comparative Analysis of Logistic Regression and Decision Tree Models by Arena, V.C., Sussman, N.B., Mazumdar, S., Yu, S., Macina, O.T.

“…Structure-activity relationship (SAR) models can be used to predict the biological activity of potential developmental toxicants whose adverse effects include…”
Get full text

Development, Characterization and Application of Predictive-Toxicology Models by Rosenkranz, H. S., Cunningham, A. R., Zhang, Y. P., Claycamp, H. G., Macina, O. T., Sussman, N. B., Grant, S. G., Klopman, G.

“…The adoption of SAR techniques for risk assessment purposes requires that the predictive performance of models be characterized and optimized. The development…”
Get full text

Decision tree SAR models for developmental toxicity based on an FDA/TERIS database by Sussman, N.B., Arena, V.C., Yu, S., Mazumdar, S., Thampatty, B.P.

“…Humans are exposed to thousands of environmental chemicals for which no developmental toxicity information is available. Structure-activity relationships…”
Get full text

Deterministic effects from occupational radiation exposures in a cohort of mayak PA workers : Data base description by CLAYCAMP, H. G, OKLADNIKOVA, N. D, TEPLYAKOV, I. I, WALD, N, AZIZOVA, T. V, BELYAEVA, Z. D, BOECKER, B. B, PESTERNIKOVA, V. S, SCOTT, B. R, SHEKHTER-LEVIN, S, SUMINA, M. V, SUSSMAN, N. B

“…Project 2.3 of the Joint Coordinating Committee on Radiation Effects Research (JCCRER) is a study of deterministic health effects among a cohort of Russia…”
Get full text

Using Alternative Comparison Populations to Assess Occupation-Related Mortality Risk: Results for the High Nickel Alloys Workers Cohort by Arena, Vincent C., Sussman, Nancy B., Redmond, Carol K., Costantino, Joseph P., Trauth, Jeanette M.

“…The focus of this article is to examine how the choice of comparison group affects the identification and interpretation of cause-specific health risks in…”
Get full text

Elevated Levels of S-Nitrosoalbumin in Preeclampsia Plasma by Tyurin, Vladimir A, Liu, Shang-Xi, Tyurina, Yulia Y, Sussman, Nancy B, Hubel, Carl A, Roberts, James M, Taylor, Robert N, Kagan, Valerian E

“…The availability of nitric oxide (NO), which is required for the normal regulation of vascular tone, may be decreased in preeclampsia, thus contributing to the…”
Get full text

Classification of chronic radiation sickness cases using neural networks and classification trees by Claycamp, H G, Sussman, N B, Okladnikova, N D, Azizova, T V, Pesternikova, V S, Sumina, M V, Teplyakov, I I

“…Chronic radiation sickness is a deterministic radiation health effect observed among the Mayak Production Association workers in Russia. In this study,…”
Get full text

Issues and findings in the evaluation of occupational risk among women high nickel alloys workers by Arena, Vincent C., Costantino, Joseph P., Sussman, Nancy B., Redmond, Carol K.

“…Background: We present the mortality experience for a cohort of women (n = 2,877) from a large epidemiologic study of production and fabrication high nickel…”
Get full text

Physicochemical and Graph Theoretical Descriptors in Developmental Toxicity SAR: A Comparative Study by Macina, O. T., Sussman, N. B., Claycamp, H. G., Grant, S. G.

“…Chemical insults to the developing fetus can lead to growth retardation, malformation, death, and functional deficits. The present study seeks to determine if…”
Get full text

Evaluating clinical case report data for SAR modeling of allergic contact dermatitis by Gealy, R, Graham, C, Sussman, N B, Macina, O T, Rosenkranz, H S, Karol, M H

“…Clinical case reports can be important sources of information for alerting health professionals to the existence of possible health hazards. Isolated case…”
Get more information

Model validation software for classification models using repeated partitioning: MVREP by Li, Wei, Arena, Vincent C., Sussman, Nancy B., Mazumdar, Sati

“…The process of assessing the prediction ability of a computational model is called model validation. For models predicting a categorical response, the…”
Get full text

A Robust Structure-Activity Relationship (SAR) Model for Esters that Cause Skin Irritation in Humans by Smith, Jeffrey S., Macina, Orest T., Sussman, Nancy B., Luster, Michael I., Karol, Meryl H.

“…A structure-activity relationship (SAR) model has been developed to discriminate skin irritant from nonirritant esters. The model is based on the…”
Get full text

CLASSIFICATION OF CHRONIC RADIATION SICKNESS CASES USING NEURAL NETOWRDS AND CLASSIFICATION TREES by Claycamp, H G, Sussman, N B, Okladnikova, N D, Azizova, T V, Pesternikova, V S, Sumina, M V, Teplyakov, I I

“…Chronic radiation sickness is a deterministic radiation health effect observed among the Mayak Production Association workers in Russia. In this study,…”
Get full text

DETERMINISTIC EFFECTS FROM OCCUPATIONAL RADIATION EXPOSURE IN A COHORT OF MAYAK PA WORKERS: DATA BASE DESCRIPTION by Claycamp, H G, Okladnikova, N D, Azizova, T V, Belyaeva, Z D, Boecker, B B, Pesternikova, V S, Scott, B R, Shekhter-Levin, S, Sumina, M V, Sussman, N B, Teplyakov, I I, Wald, N

“…Project 2.3 of the Joint Coordinating Committee on Radiation Effects Research (JCCRER) is a study of deterministic health effects among a cohort of Russia…”
Get full text

Radiographic abnormalities in relation to total dust exposure at a bauxite refinery and alumina-based chemical products plant by Townsend, M C, Sussman, N B, Enterline, P E, Morgan, W K, Belk, H D, Dinman, B D

“…A cross-sectional study of 788 male employees of an aluminum production company examined the relationship of radiographic abnormalities to smoking and dust…”
Get more information

Pulmonary function in relation to total dust exposure at a bauxite refinery and alumina-based chemical products plant by Townsend, M C, Enterline, P E, Sussman, N B, Bonney, T B, Rippey, L L

“…A cross-sectional study of 1,142 male employees at the Arkansas Operations of a large aluminum production company examined the effect on pulmonary function of…”
Get more information

Uncertainty, risk, and the role of epidemiology in public policy development by Dinman, B D, Sussman, N B

“…Risk taking is a concommitant of life--inescapable beyond the inert, sessile state. Accordingly, risk assessment is implicit for almost all human activities,…”
Get more information

Modeling adverse environmental impacts on the reproductive system by Sussman, N B, Mazumdar, S, Mattison, D R

“…When priority topics are being established for the study of women's health, it is generally agreed that one important area on which to focus research is…”
Get more information

Using alternative comparison populations to assess occupation-related mortality risk by Arena, V C, Sussman, N B, Redmond, C K, Costantino, J P, Trauth, J M

“…The focus of this article is to examine how the choice of comparison group affects the identification and interpretation of cause-specific health risks in…”
Get full text

Classification of chronic radiation sickness cases using neural networks and classification trees by CLAYCAMP, H. G, SUSSMAN, N. B, OKLADNIKOVA, N. D, AZIZOVA, T. V, PESTERNIKOVA, V. S, SUMINA, M. V, TEPLYAKOV, I. I

Get full text