Search Results - "Sussman, Carleigh"

Delivery of DNA-Based Therapeutics for Treatment of Chronic Diseases by Sussman, Carleigh, Liberatore, Rachel A, Drozdz, Marek M

“…Gene therapy and its role in the medical field have evolved drastically in recent decades. Studies aim to define DNA-based medicine as well as encourage…”
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Mitochondrial membrane depolarization enhances TRAIL-induced cell death in adult human granulosa tumor cells, KGN, through inhibition of BIRC5 by MacDonald, Julie A, Kura, Niharika, Sussman, Carleigh, Woods, Dori C

“…Cellular metabolic changes that accompany malignant transformation have been heralded as hallmark features of cancer. However, metabolic signatures between…”
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Enhancing In Vivo Electroporation Efficiency through Hyaluronidase: Insights into Plasmid Distribution and Optimization Strategies by Maji, Debnath, Miguela, Verónica, Cameron, Andrew D, Campbell, Delcora A, Sasset, Linda, Yao, Xin, Thompson, Andy T, Sussman, Carleigh, Yang, David, Miller, Robert, Drozdz, Marek M, Liberatore, Rachel A

“…Electroporation (EP) stands out as a promising non-viral plasmid delivery strategy, although achieving optimal transfection efficiency in vivo remains a…”
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Abstract 6626: Functional and molecular interrogation of a high-plasticity cell state in lung cancer by Chan, Jason Earl, Pan, Chun-Hao, Sussman, Carleigh, Styers, Hannah, Brown, Emma, Hartmann, Griffin, Meškauskaitė, Brigita, Blum, Melissa, Ding, Selena, Torborg, Stefan, Li, Zhuxuan, Joost, Simon, Rivas-Hernandez, Eliud, Norman, Thomas, Chaligne, Ronan, Yan, Yan, Tammela, Tuomas

“…Despite recent advancements in lung adenocarcinoma (LUAD) treatment, mortality remains high. Thus, a need exists for novel therapeutic concepts to enhance…”
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Abstract B008: Investigating the evolution of undifferentiated soft tissue sarcomas in a genetically engineered mouse model by Chan, Jason E., Rub, Jonathan, Sussman, Carleigh, Grbovic-huezo, Olivera, Tap, William D., Antonescu, Cristina, Singer, Sam, Betel, Doron, Tammela, Tuomas

“…Undifferentiated soft tissue sarcomas (USTS) are an aggressive class of sarcomas with few effective treatment options. Because of the rarity of these sarcomas…”
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