Search Results - "Suski, M"

Relation between mitochondrial membrane potential and ROS formation by Suski, Jan M, Lebiedzinska, Magdalena, Bonora, Massimo, Pinton, Paolo, Duszynski, Jerzy, Wieckowski, Mariusz R

“…Mitochondria are considered as the main source of reactive oxygen species (ROS) in the cell. For this reason, they have been recognized as a source of various…”
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The metabolic function of cyclin D3–CDK6 kinase in cancer cell survival by Wang, Haizhen, Nicolay, Brandon N., Chick, Joel M., Gao, Xueliang, Geng, Yan, Ren, Hong, Gao, Hui, Yang, Guizhi, Williams, Juliet A., Suski, Jan M., Keibler, Mark A., Sicinska, Ewa, Gerdemann, Ulrike, Haining, W. Nicholas, Roberts, Thomas M., Polyak, Kornelia, Gygi, Steven P., Dyson, Nicholas J., Sicinski, Piotr

“…The cyclin D3–CDK6 kinase complex, which is overactive in some cancers, inhibits two key glycolysis enzymes and thereby enhances the levels of antioxidants in…”
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p53 at the endoplasmic reticulum regulates apoptosis in a Ca²⁺-dependent manner by Giorgi, Carlotta, Bonora, Massimo, Sorrentino, Giovanni, Missiroli, Sonia, Poletti, Federica, Suski, Jan M., Ramirez, Fabian Galindo, Rizzuto, Rosario, Di Virgilio, Francesco, Zito, Ester, Pandolfi, Pier Paolo, Wieckowski, Mariusz R., Mammano, Fabio, Del Sal, Giannino, Pinton, Paolo

“…Significance Accumulating evidence has underscored the role of cytosolic p53 in promoting cell death. Different reports have revealed that p53 participates in…”
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Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells by Michowski, Wojciech, Chick, Joel M., Chu, Chen, Kolodziejczyk, Aleksandra, Wang, Yichen, Suski, Jan M., Abraham, Brian, Anders, Lars, Day, Daniel, Dunkl, Lukas M., Li Cheong Man, Mitchell, Zhang, Tian, Laphanuwat, Phatthamon, Bacon, Nickolas A., Liu, Lijun, Fassl, Anne, Sharma, Samanta, Otto, Tobias, Jecrois, Emanuelle, Han, Richard, Sweeney, Katharine E., Marro, Samuele, Wernig, Marius, Geng, Yan, Moses, Alan, Li, Cheng, Gygi, Steven P., Young, Richard A., Sicinski, Piotr

“…The cyclin-dependent kinase 1 (Cdk1) drives cell division. To uncover additional functions of Cdk1, we generated knockin mice expressing an analog-sensitive…”
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Isolation of plasma membrane–associated membranes from rat liver by Suski, Jan M, Lebiedzinska, Magdalena, Wojtala, Aleksandra, Duszynski, Jerzy, Giorgi, Carlotta, Pinton, Paolo, Wieckowski, Mariusz R

“…Dynamic interplay between intracellular organelles requires a particular functional apposition of membrane structures. The organelles involved come into close…”
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Calcium signaling around Mitochondria Associated Membranes (MAMs) by Patergnani, Simone, Suski, Jan M, Agnoletto, Chiara, Bononi, Angela, Bonora, Massimo, De Marchi, Elena, Giorgi, Carlotta, Marchi, Saverio, Missiroli, Sonia, Poletti, Federica, Rimessi, Alessandro, Duszynski, Jerzy, Wieckowski, Mariusz R, Pinton, Paolo

“…Calcium (Ca2+) homeostasis is fundamental for cell metabolism, proliferation, differentiation, and cell death. Elevation in intracellular Ca2+ concentration is…”
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Targeting cell-cycle machinery in cancer by Suski, Jan M., Braun, Marcin, Strmiska, Vladislav, Sicinski, Piotr

“…Abnormal activity of the core cell-cycle machinery is seen in essentially all tumor types and represents a driving force of tumorigenesis. Recent studies…”
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Human monocyte subsets exhibit divergent angiotensin I‐converting activity by Rutkowska‐Zapała, M., Suski, M., Szatanek, R., Lenart, M., Węglarczyk, K., Olszanecki, R., Grodzicki, T., Strach, M., Gąsowski, J., Siedlar, M.

“…Summary Immune cells may take part in the renin–angiotensin–aldosterone system (RAAS), which plays a pivotal role in the regulation of vascular tone and blood…”
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Semi-empirical determination of the nuclear quadrupole moment of 109Sn by Elantkowska, M., Ruczkowski, J., Wilman, S., Suski, M.

“…The nuclear quadrupole moment ( Q ) of 109 Sn was determined by means of hyperfine structure ( hfs ) many-body parametrization method. The hyperfine structure…”
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Metabolic effects of subchronic peripheral oxytocin administration in lean and obese zucker rats by Balazova, L, Krskova, K, Suski, M, Sisovsky, V, Hlavacova, N, Olszanecki, R, Jezova, D, Zorad, S

“…Increasing evidence indicates a role of oxytocin in controlling energy metabolism. The aim of his study was to investigate oxytocin effects on obese phenotype…”
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Multi-omics studies of intra-tumour heterogeneity in colorectal cancer by Wątor, G, Suski, M, Borys, A, Swirta, J, Chronowska, E, Barczyński, M, Wołkow, P

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The renin-angiotensin system and its vasoactive metabolite angiotensin-(1-7) in the mechanism of the healing of preexisting gastric ulcers. The involvement of Mas receptors, nitric oxide, prostaglandins and proinflammatory cytokines by Pawlik, M W, Kwiecien, S, Ptak-Belowska, A, Pajdo, R, Olszanecki, R, Suski, M, Madej, J, Targosz, A, Konturek, S J, Korbut, R, Brzozowski, T

“…The inhibition of angiotensin-converting enzyme (ACE) or the blockade of angiotensin (Ang) AT-1 receptors affords protection against acute gastric mucosal…”
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Cell-Cycle-Targeting MicroRNAs as Therapeutic Tools against Refractory Cancers by Hydbring, Per, Wang, Yinan, Fassl, Anne, Li, Xiaoting, Matia, Veronica, Otto, Tobias, Choi, Yoon Jong, Sweeney, Katharine E., Suski, Jan M., Yin, Hao, Bogorad, Roman L., Goel, Shom, Yuzugullu, Haluk, Kauffman, Kevin J., Yang, Junghoon, Jin, Chong, Li, Yingxiang, Floris, Davide, Swanson, Richard, Ng, Kimmie, Sicinska, Ewa, Anders, Lars, Zhao, Jean J., Polyak, Kornelia, Anderson, Daniel G., Li, Cheng, Sicinski, Piotr

“…Cyclins and cyclin-dependent kinases (CDKs) are hyperactivated in numerous human tumors. To identify means of interfering with cyclins/CDKs, we performed nine…”
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Angiotensin-(1-7) receptor Mas agonist ameliorates progress of atherosclerosis in apoE-knockout mice by Jawien, J, Toton-Zuranska, J, Gajda, M, Niepsuj, A, Gebska, A, Kus, K, Suski, M, Pyka-Fosciak, G, Nowak, B, Guzik, T J, Marcinkiewicz, J, Olszanecki, R, Korbut, R

“…Our interest focused on an open question whether AT-(1-7), nonpeptide receptor agonist: AVE 0991, is able to ameliorate atherosclerosis. We used an…”
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Role of the c subunit of the FO ATP synthase in mitochondrial permeability transition by Bonora, Massimo, Bononi, Angela, De Marchi, Elena, Giorgi, Carlotta, Lebiedzinska, Magdalena, Marchi, Saverio, Patergnani, Simone, Rimessi, Alessandro, Suski, Jan M., Wojtala, Aleksandra, Wieckowski, Mariusz R., Kroemer, Guido, Galluzzi, Lorenzo, Pinton, Paolo

“…The term "mitochondrial permeability transition" (MPT) refers to an abrupt increase in the permeability of the inner mitochondrial membrane to low molecular…”
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p66Shc aging protein in control of fibroblasts cell fate by Suski, Jan M, Karkucinska-Wieckowska, Agnieszka, Lebiedzinska, Magdalena, Giorgi, Carlotta, Szczepanowska, Joanna, Szabadkai, Gyorgy, Duszynski, Jerzy, Pronicki, Maciej, Pinton, Paolo, Wieckowski, Mariusz R

“…Reactive oxygen species (ROS) are wieldy accepted as one of the main factors of the aging process. These highly reactive compounds modify nucleic acids,…”
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Mitochondrial Ca2+ and apoptosis by Giorgi, Carlotta, Baldassari, Federica, Bononi, Angela, Bonora, Massimo, De Marchi, Elena, Marchi, Saverio, Missiroli, Sonia, Patergnani, Simone, Rimessi, Alessandro, Suski, Jan M, Wieckowski, Mariusz R, Pinton, Paolo

“…Abstract Mitochondria are key decoding stations of the apoptotic process. In support of this view, a large body of experimental evidence has unambiguously…”
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Angiotensinogen metabolism in rat aorta: robust formation of proangiotensin-12 by Bujak-Gizycka, B, Olszanecki, R, Suski, M, Madek, J, Stachowicz, A, Korbut, R

“…Renin-angiotensin system (RAS) plays important role in the regulation of vessel wall homeostasis. Proangiotensin-12 (proAng-12, Ang-(1-12)) is a newly…”
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Mitochondrial Ca(2+) and apoptosis by Giorgi, Carlotta, Baldassari, Federica, Bononi, Angela, Bonora, Massimo, De Marchi, Elena, Marchi, Saverio, Missiroli, Sonia, Patergnani, Simone, Rimessi, Alessandro, Suski, Jan M, Wieckowski, Mariusz R, Pinton, Paolo

“…Mitochondria are key decoding stations of the apoptotic process. In support of this view, a large body of experimental evidence has unambiguously revealed…”
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The influence of angiotensin-(1-7) peptidomimetic (AVE 0991) and nebivolol on angiotensin I metabolism in aorta of apoE-knockout mice by Olszanecki, R, Suski, M, Gebska, A, Toton-Zuranska, J, Kus, K, Madej, J, Bujak-Gizycka, B, Jawien, J, Korbut, R

“…The detrimental role of over activation of renin-angiotensin system (RAS) in atherogenesis is widely recognized. Recently, we have demonstrated that Ang-(1-7)…”
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