Search Results - "Sushnitha, Manuela"

Bio-inspired engineering of cell- and virus-like nanoparticles for drug delivery by Parodi, Alessandro, Molinaro, Roberto, Sushnitha, Manuela, Evangelopoulos, Michael, Martinez, Jonathan O., Arrighetti, Noemi, Corbo, Claudia, Tasciotti, Ennio

“…The engineering of future generations of nanodelivery systems aims at the creation of multifunctional vectors endowed with improved circulation, enhanced…”
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Cell Membrane-Based Biomimetic Nanoparticles and the Immune System: Immunomodulatory Interactions to Therapeutic Applications by Sushnitha, Manuela, Evangelopoulos, Michael, Tasciotti, Ennio, Taraballi, Francesca

“…Nanoparticle-based drug delivery systems have been synthesized from a wide array of materials. The therapeutic success of these platforms hinges upon their…”
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Biomimetic Tissue Engineering: Tuning the Immune and Inflammatory Response to Implantable Biomaterials by Taraballi, Francesca, Sushnitha, Manuela, Tsao, Christopher, Bauza, Guillermo, Liverani, Chiara, Shi, Aaron, Tasciotti, Ennio

“…Regenerative medicine technologies rely heavily on the use of well‐designed biomaterials for therapeutic applications. The success of implantable biomaterials…”
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A Novel Notch-YAP Circuit Drives Stemness and Tumorigenesis in Embryonal Rhabdomyosarcoma by Slemmons, Katherine K, Crose, Lisa E S, Riedel, Stefan, Sushnitha, Manuela, Belyea, Brian, Linardic, Corinne M

“…Rhabdomyosarcoma (RMS), a cancer characterized by skeletal muscle features, is the most common soft-tissue sarcoma of childhood. While low- and…”
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Biomimetic cellular vectors for enhancing drug delivery to the lungs by Evangelopoulos, Michael, Yazdi, Iman K., Acciardo, Stefania, Palomba, Roberto, Giordano, Federica, Pasto, Anna, Sushnitha, Manuela, Martinez, Jonathan O., Basu, Nupur, Torres, Armando, Hmaidan, Sarah, Parodi, Alessandro, Tasciotti, Ennio

“…Despite recent advances in drug delivery, the targeted treatment of unhealthy cells or tissues continues to remain a priority. In cancer (much like other…”
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Bioinspired Extracellular Vesicles: Lessons Learned From Nature for Biomedicine and Bioengineering by Zinger, Assaf, Brozovich, Ava, Pasto, Anna, Sushnitha, Manuela, Martinez, Jonathan O, Evangelopoulos, Michael, Boada, Christian, Tasciotti, Ennio, Taraballi, Francesca

“…Efficient communication is essential in all layers of the biological chain. Cells exchange information using a variety of signaling moieties, such as small…”
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Humanized Biomimetic Nanovesicles for Neuron Targeting by Zinger, Assaf, Cvetkovic, Caroline, Sushnitha, Manuela, Naoi, Tomoyuki, Baudo, Gherardo, Anderson, Morgan, Shetty, Arya, Basu, Nupur, Covello, Jennifer, Tasciotti, Ennio, Amit, Moran, Xie, Tongxin, Taraballi, Francesca, Krencik, Robert

“…Nanovesicles (NVs) are emerging as innovative, theranostic tools for cargo delivery. Recently, surface engineering of NVs with membrane proteins from specific…”
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LDL-Based Lipid Nanoparticle Derived for Blood Plasma Accumulates Preferentially in Atherosclerotic Plaque by Boada, Christian A, Zinger, Assaf, Rohen, Scott, Martinez, Jonathan O, Evangelopoulos, Michael, Molinaro, Roberto, Lu, Madeleine, Villarreal-Leal, Ramiro Alejandro, Giordano, Federica, Sushnitha, Manuela, De Rosa, Enrica, Simonsen, Jens B, Shevkoplyas, Sergey, Taraballi, Francesca, Tasciotti, Ennio

“…Apolipoprotein-based drug delivery is a promising approach to develop safe nanoparticles capable of targeted drug delivery for various diseases. In this work,…”
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Enhancing Inflammation Targeting Using Tunable Leukocyte-Based Biomimetic Nanoparticles by Zinger, Assaf, Sushnitha, Manuela, Naoi, Tomoyuki, Baudo, Gherardo, De Rosa, Enrica, Chang, Jenny, Tasciotti, Ennio, Taraballi, Francesca

“…Biomimetic nanoparticles aim to effectively emulate the behavior of either cells or exosomes. Leukocyte-based biomimetic nanoparticles, for instance,…”
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Rapamycin-Loaded Biomimetic Nanoparticles Reverse Vascular Inflammation by Boada, Christian, Zinger, Assaf, Tsao, Christopher, Zhao, Picheng, Martinez, Jonathan O., Hartman, Kelly, Naoi, Tomoyuki, Sukhovershin, Roman, Sushnitha, Manuela, Molinaro, Roberto, Trachtenberg, Barry, Cooke, John P., Tasciotti, Ennio

“…Through localized delivery of rapamycin via a biomimetic drug delivery system, it is possible to reduce vascular inflammation and thus the progression of…”
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Engineering Leukocyte Mimicking Nanoparticles for Targeted Delivery in Triple-Negative Breast Cancer: Biological versus Cargo-Based Approach by Sushnitha, Manuela

“…Nanoparticles offer the ability to achieve targeted drug delivery across many disease contexts, especially difficult to treat cancers like triple-negative…”
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Lymph node biophysical remodeling is associated with melanoma lymphatic drainage by Rohner, Nathan Andrew, McClain, Jacob, Tuell, Sara Lydia, Warner, Alex, Smith, Blair, Yun, Youngho, Mohan, Abhinav, Sushnitha, Manuela, Thomas, Susan Napier

“…ABSTRACT Tissue remodeling is a characteristic of many solid tumor malignancies including melanoma. By virtue of tumor lymphatic transport, remodeling pathways…”
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Abstract 5830: A novel Notch-YAP circuit drives stemness and tumorigenesis in embryonal rhabdomyosarcoma by Slemmons, Katherine K., Crose, Lisa E.S., Riedel, Stefan, Sushnitha, Manuela, Belyea, Brian, Linardic, Corinne M.

“…Introduction: Rhabdomyosarcoma (RMS), a tumor characterized by skeletal muscle features, is the most common soft tissue sarcoma in children and adolescents…”
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Humanized Biomimetic Nanovesicles for Neuron Targeting (Adv. Sci. 19/2021) by Zinger, Assaf, Cvetkovic, Caroline, Sushnitha, Manuela, Naoi, Tomoyuki, Baudo, Gherardo, Anderson, Morgan, Shetty, Arya, Basu, Nupur, Covello, Jennifer, Tasciotti, Ennio, Amit, Moran, Xie, Tongxin, Taraballi, Francesca, Krencik, Robert

“…Humanized Biomimetic Nanovesicles In article number 2101437, Assaf Zinger, Francesca Taraballi, Robert Krencik, and co‐workers optimize and validate the…”
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